Clinical Trials

NCT07405086 | RECRUITING | PHASE4

160 participants

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-07-31

Completion:

2028-12-31

Conditions

• Advanced Biliary Tract Carcinoma
• Advanced Head and Neck Squamous Cell Carcinoma
• Advanced Hepatocellular Carcinoma
• Advanced Lung Non-Small Cell Carcinoma
• Advanced Malignant Solid Neoplasm
• Advanced Melanoma
• Advanced Renal Cell Carcinoma
• Metastatic Biliary Tract Carcinoma
• Metastatic Head and Neck Squamous Cell Carcinoma
• Metastatic Hepatocellular Carcinoma
• Metastatic Lung Non-Small Cell Carcinoma
• Metastatic Malignant Solid Neoplasm
• Metastatic Melanoma
• Metastatic Renal Cell Carcinoma
• Recurrent Head and Neck Squamous Cell Carcinoma
• Stage III Hepatocellular Carcinoma AJCC v8
• Stage III Lung Cancer AJCC v8
• Stage III Renal Cell Cancer AJCC v8
• Stage IV Hepatocellular Carcinoma AJCC v8
• Stage IV Lung Cancer AJCC v8
• Stage IV Renal Cell Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT07403721 | RECRUITING | PHASE1

464 participants

AMG 436 as Monotherapy and Combination Therapy in Participants With MSI-H/dMMR Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-04-08

Completion:

2028-06-28

Conditions

• Metastatic or Locally Advanced Solid Tumors With Microsatellite Instability-high (MSI-H) or Mismatched Repair Deficiency (dMMR)

Interventions

• DRUG

No Results Yet

NCT07399678 | RECRUITING | PHASE1

180 participants

Study of ALV-100 to Assess Safety, Tolerability, and PK/PD in Overweight/Obese Participants With or Without T2D

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-12-29

Completion:

2027-04-30

Conditions

• Overweight or Obese Adults
• Overweight or Obese, Type 2 Diabetes

Interventions

• DRUG

No Results Yet

NCT07398846 | COMPLETED | PHASE3

134 participants

Efficacy of a Stannous Fluoride Toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reducing Established Dental Plaque and Gingivitis.

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-01-26

Completion:

2026-04-29

Conditions

• Plaque

Interventions

• DRUG

No Results Yet

NCT07398079 | RECRUITING

30 participants

Pilot Observational Study of an Integrative Cure Stay Program

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2025-10-06

Completion:

2026-12-31

Conditions

• Breast Cancer
• Gynecologic Cancer

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT07394855 | RECRUITING

300 participants

Mechanisms of Persistent Fatigue

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2026-04-28

Completion:

2027-12-31

Conditions

• Fatigue Post Viral

No Results Yet

NCT07394803 | RECRUITING | NA

60 participants

Physical Activity and Pregnant Women at Increased Social Risk: a Feasibility Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-02-01

Completion:

2026-09-30

Conditions

• Pregnancy

Interventions

• BEHAVIORAL

No Results Yet

NCT07392216 | RECRUITING

440 participants

Functional Ovarian Reserve in Sickle Cell Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2026-06-30

Completion:

2028-07-31

Conditions

• Sickle Cell Disease

No Results Yet

NCT07392190 | RECRUITING | PHASE3

900 participants

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-02-10

Completion:

2028-06-30

Conditions

• Overweight
• Obesity

Interventions

• DRUG

No Results Yet

NCT07390773 | NOT_YET_RECRUITING | NA

495 participants

Building Relationship, Improving Dialogue, and Growing Empathy (BRIDGE): An Intervention to Support Decision Making for Critically Ill Children

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-07-31

Completion:

2028-08-31

Conditions

• Decision Making
• Neonatal Critical Illness
• Pediatric Critical Illness

Interventions

• BEHAVIORAL

No Results Yet

NCT07390578 | NOT_YET_RECRUITING | PHASE4

50 participants

Upneeq vs. Lumify Ptosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-12-01

Completion:

2027-08-01

Conditions

• Acquired Ptosis

Interventions

• DRUG

No Results Yet

NCT07384585 | RECRUITING | NA

30 participants

Feasibility of Light Therapy in the Pediatric Intensive Care Unit (ICU)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-03-26

Completion:

2027-01-31

Conditions

• Circadian Dysregulation
• Light Exposure
• Pediatric Critical Illness

Interventions

• OTHER

No Results Yet

NCT07383987 | COMPLETED

216 participants

Genital Hygiene, Toilet Behaviors, and LUTS in Normal Weight and Obese Women

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2025-12-01

Completion:

2026-03-15

Conditions

• Lower Urinary Tract Symptoms (LUTS)
• Genital Hygiene
• Obesity
• Toilet Training
• Body Awareness
• Overweight

No Results Yet

NCT07380906 | RECRUITING

1200 participants

geniculaR Artery eMBolization for Knee Osteoarthritis (RAMBO) Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2025-07-16

Completion:

2030-04-30

Conditions

• Knee Osteoarthristis

Interventions

• PROCEDURE

No Results Yet

NCT07379125 | RECRUITING | PHASE1

18 participants

Therapeutic RSK1 Targeting in Myelofibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-05-20

Completion:

2028-12-31

Conditions

• Myelofibrosis

Interventions

• DRUG

No Results Yet

NCT07377487 | RECRUITING | NA

51 participants

TheraSphere Japan Pre-Market Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-01-22

Completion:

2027-06-30

Conditions

• Liver Neoplasms

Interventions

• DEVICE

No Results Yet

NCT07375914 | RECRUITING | NA

782 participants

Comprehensive Biopsychosocial Approach for Acute Low Back Pain Management in the Emergency Department: a Stepped-wedge Cluster-randomized Clinical Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-04-14

Completion:

2027-04-14

Conditions

• Non-traumatic Low Back Pain

Interventions

• OTHER

No Results Yet

NCT07375147 | RECRUITING | NA

62 participants

Transanal vs Transvaginal Rectal Resection for Anterior Rectocele

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-06-14

Completion:

2027-01-01

Conditions

• Rectocele; Female

Interventions

• PROCEDURE

No Results Yet

NCT07374692 | RECRUITING | NA

80 participants

Observational Study of Responses to Treatments in Advanced Central Nervous System (CNS) Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-02-04

Completion:

2030-12-30

Conditions

• Recurrent CNS Tumors
• Brain Cancer
• Gliomas
• IDH-wildtype Gliomas
• IDH-mutant Gliomas
• Rare CNS Tumor

Interventions

• OTHER

No Results Yet

NCT07374679 | RECRUITING

21 participants

Long-Term Follow-up Study to Evaluate Long-Term Safety and Efficacy of Allogenic Umbilical Cord-derived Mesenchymal Stem Cell in Patients With Rotator Cuff Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2026-01-27

Completion:

2031-05-30

Conditions

• Rotator Cuff Disease

No Results Yet

NCT07373496 | RECRUITING

20 participants

Patient Position Monitoring System for Beam Gated Radiation Therapy of Malignancies of the Chest and Upper Abdomen

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2026-05-20

Completion:

2027-06-30

Conditions

• Radiotherapy
• Radiotherapy, Image-Guided

Interventions

• DEVICE

No Results Yet

NCT07372872 | RECRUITING | NA

30 participants

Feasibility Testing of the "MyGlucoCare" Smartphone App for Women With Gestational Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-05-01

Completion:

2026-11-30

Conditions

• Gestational Diabetes Mellitus (GDM)

Interventions

• DEVICE

No Results Yet

NCT07369076 | RECRUITING | PHASE1/PHASE2

80 participants

A Clinical Trial to Evaluate NB-4746 in Participants With Amyotrophic Lateral Sclerosis.

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-03-04

Completion:

2027-04-30

Conditions

• Amyotrophic Lateral Sclerosis (ALS)

Interventions

• DRUG

No Results Yet

NCT07369011 | RECRUITING | PHASE3

800 participants

A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-02-10

Completion:

2028-03-31

Conditions

• Sleep Apnea, Obstructive
• Obesity
• Overweight

Interventions

• DRUG

No Results Yet

NCT07368959 | RECRUITING | PHASE3

120 participants

AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-02-19

Completion:

2027-06-30

Conditions

• Corneal Edema
• Corneal Endothelial Dysfunction
• Fuchs Endothelial Corneal Dysfunction
• Pseudophakic Bullous Keratopathy (PBK)

Interventions

• DRUG
• OTHER

No Results Yet

NCT07368205 | RECRUITING

350 participants

Preoperative Risk Stratification in Endometrial Cancer for Tailoring Lymph Node Staging

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2026-02-15

Completion:

2028-02-29

Conditions

• Endometrial Cancer

Interventions

• OTHER

No Results Yet

NCT07367893 | RECRUITING

10000 participants

Exercise Echocardiography Registry for Ischemic and Non-Ischemic Heart Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2026-04-01

Completion:

2030-12-31

Conditions

• Ischemic Heart Diease
• Non-ischemic Heart Disease

No Results Yet

NCT07365813 | ENROLLING_BY_INVITATION | NA

850 participants

Testing Alcohol Cancer Risk Messages

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-04-21

Completion:

2028-03-30

Conditions

• Alcohol
• Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT07364617 | RECRUITING | PHASE2

35 participants

Fecal Microbiota Transplantation for Steroid-Refractory Acute GI GVHD

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-04-29

Completion:

2028-02-28

Conditions

• Graft vs Host Disease

Interventions

• BIOLOGICAL

No Results Yet

NCT07362082 | NOT_YET_RECRUITING | NA

470 participants

A Clinical Trial of Telehealth Treatment for Opioid Use Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-06-01

Completion:

2027-10-01

Conditions

• Opioid Use Disorder

Interventions

• DEVICE

No Results Yet

NCT07357415 | RECRUITING | PHASE3

600 participants

A Study of Retatrutide (LY3437943) in Participants Without Type 2 Diabetes Who Have Obesity or Overweight

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-01-24

Completion:

2028-10-31

Conditions

• Obesity
• Overweight

Interventions

• DRUG

No Results Yet

NCT07356284 | RECRUITING | PHASE3

342 participants

Emergent Large Vessel Occlusion Endovascular Rescue Therapy With Underlying Intracranial Stenosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-05-19

Completion:

2030-06-01

Conditions

• Brain Stroke
• Stenting Treatment
• Acute Ischemic Stroke

Interventions

• PROCEDURE
• DEVICE

No Results Yet

NCT07355205 | NOT_YET_RECRUITING | PHASE2

26 participants

First-Line Ipilimumab Plus Nivolumab and Nogapendekin Alfa Inbakicept (N-803) in Patients With Stage IV or Recurrent Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-06-30

Completion:

2032-06-30

Conditions

• Non-small Cell Lung Cancer Stage IV
• Non-small Cell Lung Cancer Recurrent

Interventions

• DRUG

No Results Yet

NCT07353931 | RECRUITING | PHASE3

900 participants

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-02-09

Completion:

2028-03-31

Conditions

• Osteoarthritis
• Overweight or Obesity

Interventions

• DRUG

No Results Yet

NCT07349069 | RECRUITING | PHASE3

5500 participants

A Phase III Trial Comparing HRS-8080 With Standard Endocrine Therapy in Patients With Intermediate or High Risk Early Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-03-04

Completion:

2030-12-31

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT07348692 | RECRUITING | PHASE3

2195 participants

Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-01-20

Completion:

2027-06-07

Conditions

• Pneumococcal Immunization
• Healthy Volunteers

Interventions

• BIOLOGICAL

No Results Yet

NCT07345481 | RECRUITING

40 participants

Stimulus Equivalence Learning in Acquired Brain Injury.

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2026-01-29

Completion:

2026-06-30

Conditions

• Acquired Brain Injury (Including Stroke)

No Results Yet

NCT07345351 | ENROLLING_BY_INVITATION | NA

62 participants

Lifestyle Counseling vs. Clinical Pilates in Women With Temporomandibular Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-07-17

Completion:

2025-10-17

Conditions

• Counseling
• Health Counseling
• Behavior Therapy

Interventions

• BEHAVIORAL

No Results Yet

NCT07344519 | COMPLETED | EARLY_PHASE1

8 participants

The Safety and Tolerability Study With ER2001 Intravenous Injection Repetitive Treatment in Adults With Early Manifest Huntington's Disease.

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-06-25

Completion:

2025-06-01

Conditions

• Huntington Disease

Interventions

• DRUG

No Results Yet

NCT07340216 | COMPLETED | PHASE1

22 participants

Maximal Usage Pharmacokinetics and Safety Study of ARQ-154 Foam 0.3% in Pediatric Participants With Scalp and Body Psoriasis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-12-15

Completion:

2026-04-30

Conditions

• Psoriasis

Interventions

• DRUG

No Results Yet