Clinical Trials

NCT06990477 | RECRUITING | NA

2400 participants

Effect of EIT-guided PEEP in ARDS Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-05-13

Completion:

2029-01-19

Conditions

• ARDS (Acute Respiratory Distress Syndrome)

Interventions

• DEVICE

No Results Yet

NCT06989281 | ENROLLING_BY_INVITATION | NA

1000 participants

Evaluation of a Primary Care Based Lifestyle Medicine Clinic at UAB

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-05-03

Completion:

2026-12-31

Conditions

• Obesity and Obesity-related Medical Conditions

Interventions

• BEHAVIORAL

No Results Yet

NCT06986083 | RECRUITING | PHASE3

800 participants

A Study of Changes to Prostate Procedures

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-05-19

Completion:

2028-05-31

Conditions

• Prostate Cancer

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT06984848 | RECRUITING | NA

100 participants

Effect of Enzymatic-Containing Mouth Spray (Oral7®) on Xerostomia Symptoms, Salivary Flow Rate, and Oral Health-Related Quality of Life in Older Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-09-18

Completion:

2026-12-01

Conditions

• Xerostomia
• Geriatric

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT06984627 | RECRUITING | PHASE2

30 participants

A Study to Investigate the Efficacy and Safety of Rilzabrutinib in Adult Participants With Graves' Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-09-02

Completion:

2026-08-25

Conditions

• Graves' Disease

Interventions

• DRUG

No Results Yet

NCT06984341 | NOT_YET_RECRUITING | PHASE1

162 participants

A Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Pharmacodynamics, and Efficacy of P-CD19CD20-ALLO1 in Participants With Severe, Treatment-refractory Systemic Lupus Erythematosus (SLE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-06-30

Completion:

2033-11-01

Conditions

• Systemic Lupus Erythematosus

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06981000 | COMPLETED | NA

120 participants

A Feasibility Study of Nature-based Health Interventions for People With Mild to Moderate Anxiety, Depression and Stress

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-02-01

Completion:

2026-04-30

Conditions

• Anxiety
• Anxiety Disorders
• Depression - Major Depressive Disorder
• Depressive Disorder
• Stress, Psychologic

Interventions

• BEHAVIORAL

No Results Yet

NCT06980649 | RECRUITING | PHASE1

15 participants

Study of BHV-1300 in Graves' Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-08-21

Completion:

2027-09-30

Conditions

• Graves Disease

Interventions

• DRUG

No Results Yet

NCT06978751 | COMPLETED

271 participants

Development of a Risk Assessment Tool for Incontinence-associated Dermatitis (IAD): a Cohort Study on the Predictive Performance of Risk Factors for IAD

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2025-05-13

Completion:

2026-05-18

Conditions

• Incontinence Associated Dermatitis

No Results Yet

NCT06978621 | ACTIVE_NOT_RECRUITING | PHASE3

36 participants

Immunogenicity and Safety of I-HAV in Healthy Thai Children and Adolescents Lacking Protective Antibody After L-HAV

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-05-25

Completion:

2025-06-22

Conditions

• Hepatitis A
• Hepatitis A Virus
• Vaccine-Preventable Diseases

Interventions

• BIOLOGICAL

No Results Yet

NCT06978322 | COMPLETED

30 participants

Comparative Study Between Immediate Surgery Versus Neoadjuvant Chemotherapy for Management of Resectable Pancreatic Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2025-02-01

Completion:

2026-02-01

Conditions

• Surgery
• Neoadjuvant Chemotherapy
• Management
• Resectable Pancreatic Cancer

Interventions

• PROCEDURE

No Results Yet

NCT06977737 | RECRUITING | PHASE1/PHASE2

72 participants

A Study of ATTR-01 in Participants With Select Epithelial Solid Tumours

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-03-21

Completion:

2029-12-31

Conditions

• Solid Tumor, Adult

Interventions

• DRUG

No Results Yet

NCT06977490 | COMPLETED | NA

42 participants

Human Bioequivalence Study of Amphotericin B Liposome for Injection

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-05-13

Completion:

2025-10-07

Conditions

• Invasive Fungal Infections
• Neutropenic Fever
• Visceral Leishmaniasis

Interventions

• DRUG

No Results Yet

NCT06976840 | RECRUITING | NA

200 participants

Rapid Antidepressant Dynamics in Acute Neuromodulation Treatments

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-05-15

Completion:

2030-08-01

Conditions

• Depression
• Major Depressive Disorder

Interventions

• DEVICE

No Results Yet

NCT06972056 | RECRUITING | PHASE4

1335 participants

Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-07-09

Completion:

2029-03-01

Conditions

• Migraine

Interventions

• DRUG

No Results Yet

NCT06966700 | RECRUITING | PHASE3

2400 participants

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-06-30

Completion:

2033-03-23

Conditions

• Breast Neoplasms
• Triple Negative Breast Neoplasms
• HR Low-Positive/HER2-Negative Breast Neoplasms

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06963931 | RECRUITING | NA

128 participants

Change 4 Better (C4B)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-05-01

Completion:

2027-12-31

Conditions

• Problem Gambling

Interventions

• BEHAVIORAL

No Results Yet

NCT06963905 | RECRUITING | PHASE1/PHASE2

60 participants

Saci Nivo Rela for TNBC

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-12-29

Completion:

2030-12-31

Conditions

• Metastatic Triple-negative Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06962800 | RECRUITING | PHASE3

180 participants

A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Primary Membranous Nephropathy (PMN)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-05-22

Completion:

2028-12-29

Conditions

• Primary Membranous Nephropathy

Interventions

• DRUG

No Results Yet

NCT06959641 | RECRUITING | PHASE2

33 participants

XL092 for the Treatment of Locally Advanced or Metastatic Radioiodine Refractory Differentiated Thyroid Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-06-06

Completion:

2028-09-11

Conditions

• Locally Advanced Differentiated Thyroid Gland Carcinoma
• Locally Advanced Poorly Differentiated Thyroid Gland Carcinoma
• Locally Advanced Thyroid Gland Follicular Carcinoma
• Locally Advanced Thyroid Gland Oncocytic Carcinoma
• Locally Advanced Thyroid Gland Papillary Carcinoma
• Metastatic Differentiated Thyroid Gland Carcinoma
• Metastatic Poorly Differentiated Thyroid Gland Carcinoma
• Metastatic Thyroid Gland Follicular Carcinoma
• Metastatic Thyroid Gland Oncocytic Carcinoma
• Metastatic Thyroid Gland Papillary Carcinoma
• Refractory Differentiated Thyroid Gland Carcinoma
• Refractory Poorly Differentiated Thyroid Gland Carcinoma
• Refractory Thyroid Gland Follicular Carcinoma
• Refractory Thyroid Gland Oncocytic Carcinoma
• Refractory Thyroid Gland Papillary Carcinoma
• Stage III Differentiated Thyroid Gland Carcinoma AJCC v8
• Stage III Thyroid Gland Follicular Carcinoma AJCC v8
• Stage III Thyroid Gland Papillary Carcinoma AJCC v8
• Stage IV Differentiated Thyroid Gland Carcinoma AJCC v8
• Stage IV Thyroid Gland Follicular Carcinoma AJCC v8
• Stage IV Thyroid Gland Papillary Carcinoma AJCC v8

Interventions

• PROCEDURE
• OTHER
• DRUG

No Results Yet

NCT06959511 | RECRUITING | PHASE2

45 participants

Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-07-22

Completion:

2028-03-01

Conditions

• Neoadjuvant Treatment
• Thyroid Cancer

Interventions

• DRUG

No Results Yet

NCT06955169 | SUSPENDED | PHASE2

153 participants

Comparing the Radiopharmaceutical Drug, [177Lu]Lu-DOTATATE, to Standard of Care Treatment for Patients With Meningioma That Has Come Back After Prior Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-12-24

Completion:

2029-08-31

Conditions

• Intracranial Meningioma

Interventions

• DRUG
• OTHER

No Results Yet

NCT06954480 | RECRUITING | PHASE2

140 participants

Investigating Datopotamab Deruxtecan Plus Durvalumab Versus Datopotamab Deruxtecan in Patients With PDL1-negative Metastatic Triple-negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-10-27

Completion:

2028-02-29

Conditions

• Triple Negative Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06953089 | RECRUITING | PHASE2

450 participants

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-07-18

Completion:

2030-06-30

Conditions

• Solid Tumors

Interventions

• DRUG

No Results Yet

NCT06952725 | NOT_YET_RECRUITING | NA

120 participants

Chatbot for Online Support Groups to Treat Tobacco Addiction

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-12-01

Completion:

2028-06-01

Conditions

• Tobacco Dependence
• Tobacco Use Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT06952504 | RECRUITING | PHASE3

1123 participants

A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-05-22

Completion:

2032-05-24

Conditions

• Endometrial Cancer

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06950385 | RECRUITING | PHASE3

168 participants

Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-07-18

Completion:

2030-07-31

Conditions

• Familial Adenomatous Polyposis (FAP)

Interventions

• DRUG

No Results Yet

NCT06950294 | RECRUITING | EARLY_PHASE1

34 participants

iNO300 Therapy in Critically Ill Patients With Pneumonia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-02-23

Completion:

2026-12-31

Conditions

• Critical Illness
• Pneumonia

Interventions

• DRUG
• OTHER

No Results Yet

NCT06949007 | RECRUITING | NA

50 participants

Yoga for Persistent Post-Surgical Pain (PPSP)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-03-12

Completion:

2028-09-30

Conditions

• Persistent Post-surgical Pain

Interventions

• BEHAVIORAL

No Results Yet

NCT06948799 | RECRUITING | PHASE1

64 participants

A Study to Evaluate the Safety and Tolerability of Single and Multiple Dose of STSP-0902 in Healthy Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-05-08

Completion:

2026-07-31

Conditions

• Oligozoospermia

Interventions

• DRUG

No Results Yet

NCT06946680 | NOT_YET_RECRUITING | PHASE1

24 participants

IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Newly Diagnosed and Recurrent Pediatric High-grade Glioma (pHGG) and Newly Diagnosed Diffuse Intrinsic Pontine Glioma (ndDIPG)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-07-31

Completion:

2030-12-31

Conditions

• High-grade Glioma
• Diffuse Intrinsic Pontine Glioma

Interventions

• BIOLOGICAL

No Results Yet

NCT06939478 | COMPLETED

112 participants

AI Powered Mapping Technology for Identifying Arrhythmias

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2025-08-27

Completion:

2026-03-05

Conditions

• Arrhythmias, Cardiac

Interventions

• DEVICE

No Results Yet

NCT06939348 | RECRUITING | NA

60 participants

Ultrasound Stimulation for Patients in a Disorder of Consciousness

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-04-26

Completion:

2028-03-28

Conditions

• Consciousness Disorders
• Disorders of Consciousness Due to Severe Brain Injury

Interventions

• DEVICE

No Results Yet

NCT06938789 | RECRUITING | NA

198 participants

How Bleeding Affects Delirium in Older Patients With Hip Fractures: The IMPROVE-HIP Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-04-24

Completion:

2026-12-31

Conditions

• Bleeding
• Hip Fracture
• Delirium - Postoperative

Interventions

• OTHER

No Results Yet

NCT06938412 | RECRUITING | NA

120 participants

Exercise Activity Intervention With Sensor-Based Engagement in Patients With Atrial Fibrillation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-06-01

Completion:

2027-03-31

Conditions

• Atrial Fibrillation
• Arrhythmias, Cardiac
• Cardiovascular Diseases

Interventions

• DEVICE

No Results Yet

NCT06937229 | RECRUITING | PHASE3

600 participants

A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-12-02

Completion:

2029-06-22

Conditions

• Alzheimer Disease
• Agitation

Interventions

• DRUG

No Results Yet

NCT06935097 | ENROLLING_BY_INVITATION | NA

25 participants

Mediterranean Diet Intervention Among Men at LBJ Hospital With Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-10-24

Completion:

2029-03-31

Conditions

• Prostate Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT06930859 | RECRUITING

2766 participants

Non-interventional Study to Assess the Effectiveness and Safety of Ribociclib in the Adjuvant Therapy of Hormone Receptor Positive (HR+) HER2-negative Stage II and III Breast Cancer in Real Clinical Practice in Russia

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2025-12-03

Completion:

2032-12-31

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06929520 | ACTIVE_NOT_RECRUITING | NA

500 participants

The Development and Evaluation of a Culturally Grounded ENDS Intervention for Rural Hawaiian Youth

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-10-15

Completion:

2027-05-15

Conditions

• E-cigarette Use
• Substance Use

Interventions

• BEHAVIORAL

No Results Yet

NCT06925737 | RECRUITING | PHASE3

1440 participants

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-05-13

Completion:

2028-06-26

Conditions

• Prostate Cancer
• Prostatic Neoplasms

Interventions

• DRUG

No Results Yet