Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery
NCT06959511 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 45
Last updated 2026-05-22
Summary
To look at the effectiveness of zanzalintinib, followed by surgery, in treating advanced thyroid cancer. The safety of this treatment will also be studied.
Conditions
- Neoadjuvant Treatment
- Thyroid Cancer
Interventions
- DRUG
-
Zanzalintinib
Given by po
Sponsors & Collaborators
- collaborator INDUSTRY
-
M.D. Anderson Cancer Center
lead OTHER
Principal Investigators
-
Mark Zafereo, MD · M.D. Anderson Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-07-22
- Primary Completion
- 2028-03-01
- Completion
- 2030-10-01
- FDA Drug
- Yes
Countries
- United States
Study Locations
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