Clinical Trials

NCT07589530 | RECRUITING | PHASE1/PHASE2

60 participants

Phase 1/2 Study of EB-NK-301 (Allogeneic TROP2-CAR NK Cells) in Advanced TROP2-Expressing Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2026-03-02

Completion:

2027-02-14

Conditions

• Advanced Solid Tumors
• Metastatic Solid Tumors
• TROP2-Expressing Solid Tumors

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT07589517 | RECRUITING | PHASE1/PHASE2

48 participants

Dual-Targeting CAR-NK Cells in Biomarker-Selected Advanced Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2026-02-02

Completion:

2027-03-14

Conditions

• Colorectal Cancer
• Metastatic Colorectal Adenocarcinoma
• Unresectable Colorectal Cancer

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT07589504 | NOT_YET_RECRUITING

5200 participants

The Impact of First Responder Intervention on Survival in Out-of-Hospital Cardiac Arrest in Emilia-Romagna Region

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-15

Start Date:

2026-05-31

Completion:

2026-12-31

Conditions

• Cardiac Arrest (CA)

No Results Yet

NCT07589491 | NOT_YET_RECRUITING | NA

60 participants

Intertransverse Process Block Versus M-TAPA Block After Laparoscopic Cholecystectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2026-11-15

Completion:

2027-09-30

Conditions

• Intertransverse Process Block
• Mtapa Block
• Laparoscopic Cholecystectomy
• Postoperative Pain
• Regional Anaesthesia

Interventions

• PROCEDURE

No Results Yet

NCT07589465 | RECRUITING | NA

150 participants

Oral Lactulose for Gastrointestinal Recovery After Complex Appendectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2026-04-30

Completion:

2027-06-30

Conditions

• Ileus Postoperative
• Gastrointestinal Function
• Complicated Appendicitis

Interventions

• DRUG

No Results Yet

NCT07589452 | NOT_YET_RECRUITING | NA

70 participants

Impact of Allometric Pacing Rate on Ventricular Diastolic Function and Cerebral Blood Flow in Hypertensive Patients With Sinus Node Dysfunction

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2026-05-15

Completion:

2028-01-31

Conditions

• Bradycardia

Interventions

• DEVICE

No Results Yet

NCT07589426 | COMPLETED | NA

16 participants

Horizontal Ridge Augmentation in Maxillary Esthetic Zone Using Bovine Bone Graft Versus Extended Sticky Bone With Simultaneous Implant Placement

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2025-11-01

Completion:

2026-04-01

Conditions

• Horizontal Alveolar Ridge Resorption

Interventions

• PROCEDURE

No Results Yet

NCT07589413 | RECRUITING

150 participants

Association Between Irrigation Fluid Absorption and Perioperative cfDNA Dynamics After TURBT

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-15

Start Date:

2026-04-01

Completion:

2027-04-01

Conditions

• Bladder (Urothelial, Transitional Cell) Cancer
• Bladder Cancer Recurrence
• Progression of Bladder Cancer
• Transurethral Resection of Bladder Tumor
• Urothelial Carcinoma of the Bladder

Interventions

• OTHER

No Results Yet

NCT07589400 | NOT_YET_RECRUITING | PHASE1

24 participants

Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Characteristics of ACT500 in Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Complicated With Chronic Hepatitis B

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2026-05-30

Completion:

2027-03-30

Conditions

• Metabolic Dysfunction-associated Steatotic Liver Disease
• Chronic Hepatitis b

Interventions

• DRUG

No Results Yet

NCT07589387 | NOT_YET_RECRUITING | NA

2800 participants

Hypertension Treatment in Nigeria: Hypertension Diabetes Integration Study- Formative Aim 3

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2026-05-01

Completion:

2029-04-30

Conditions

• Diabete Mellitus

Interventions

• OTHER
• DRUG
• DEVICE
• BEHAVIORAL

No Results Yet

NCT07589361 | NOT_YET_RECRUITING

38 participants

Safety and Efficacy of Vertebral Body-Sparing Craniospinal Irradiation With Proton Therapy in Pediatric Tumors

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-15

Start Date:

2026-04-30

Completion:

2029-06-30

Conditions

• Pediatric Central Nervous System Tumors
• Medulloblastoma
• Germinoma
• Ependymoma
• Atypical Teratoid/Rhabdoid Tumor (AT/RT)

Interventions

• RADIATION

No Results Yet

NCT07589348 | NOT_YET_RECRUITING

72 participants

POCD After Major Gynecologic Surgery

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-15

Start Date:

2026-05-01

Completion:

2026-09-15

Conditions

• Postoperative Cognitive Dysfunction
• Perioperative Neurocognitive Disorder

No Results Yet

NCT07589335 | ACTIVE_NOT_RECRUITING | NA

160 participants

Supplying Useful Perimenopause Through Post-menopause Online Resources and Tools

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2026-03-06

Completion:

2026-04-02

Conditions

• Women
• Community Health Workers
• Health
• Menopause
• Hispanic or Latino
• African Americans

Interventions

• OTHER

No Results Yet

NCT07589322 | RECRUITING | NA

120 participants

Comparative Observation of Metabolic and Pharmacologic Adipose Remodeling With Enhanced Incretin AgonisTs

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2026-03-31

Completion:

2028-09-30

Conditions

• Obesity and Metabolic Syndrome

Interventions

• DRUG

No Results Yet

NCT07589309 | COMPLETED | NA

44 participants

Comparative Effectiveness of Blood Flow Restriction With or Without Total Motion Release in ACL Rehabilitation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2025-11-02

Completion:

2026-04-21

Conditions

• ACL Injury
• ACL Reconstruction

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT07589296 | RECRUITING | NA

40 participants

Robot-Assisted Gait Training vs NMES in Parkinson's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2026-04-15

Completion:

2026-04-15

Conditions

• Parkinson Disease (PD)

Interventions

• OTHER
• DEVICE

No Results Yet

NCT07589283 | ENROLLING_BY_INVITATION

150 participants

CLIME-CJD: A Multimodal Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-15

Start Date:

2022-01-01

Completion:

2031-12-31

Conditions

• Creutzfeldt-Jakob Disease (CJD) | Prion Disease

Interventions

• OTHER

No Results Yet

NCT07589270 | NOT_YET_RECRUITING | NA

60 participants

Direct Selective Laser Trabeculoplasty (DSLT) for Patients With Glaucoma or Ocular Hypertension Previously Treated With SLT

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2026-04-30

Completion:

2027-01-31

Conditions

• Ocular Hypertension Glaucoma
• POAG

Interventions

• DEVICE

No Results Yet

NCT07589257 | RECRUITING | PHASE2

10 participants

A Study of VRT106 in Combination With Radiotherapy in Adult Patients With Diffuse Midline Glioma / Diffuse Intrinsic Pontine Glioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2026-05-07

Completion:

2028-06-30

Conditions

• Diffuse Midline Glioma, H3 K27M-Mutant
• Diffuse Intrinsic Pontine Glioma

Interventions

• DRUG

No Results Yet

NCT07589244 | RECRUITING | PHASE2/PHASE3

66 participants

A Study of VRT106, Combined With Camrelizumab, and Apatinib for Advanced HCC

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2026-05-13

Completion:

2028-12-31

Conditions

• HCC

Interventions

• DRUG

No Results Yet

NCT07589231 | RECRUITING | NA

38 participants

Effects of Carbon Fiber Insoles on CMJ and Sprint Performance

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2025-10-30

Completion:

2026-06-15

Conditions

• Healthy
• Sportsman
• Prevention
• Performance
• Healthy Adult Man
• Sports Performance
• Athletic Performance and Injury Risk

Interventions

• DEVICE

No Results Yet

NCT07589218 | RECRUITING

38 participants

Assessment of Weight-bearing Ankle Range of Motion Using the Ankle Test and Lower Body Test and Its Relationship With Ligamentous Hyperlaxity in Child Basketball Players Aged 8 to 15 Years

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-15

Start Date:

2025-12-09

Completion:

2026-05-15

Conditions

• Ligamentous Hypermobility of the Toe
• Children Basketball Players

No Results Yet

NCT07589205 | RECRUITING | PHASE1

493 participants

Study of IBI3028 in Participants With Locally Advanced, Unresectable, or Metastatic Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2026-03-31

Completion:

2027-06-30

Conditions

• Solid Tumor
• Colorectal Cancer
• Non-small Cell Lung Cancer
• Pancreatic Ductal Adenocarcinoma
• Head and Neck Squamous Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT07589192 | NOT_YET_RECRUITING

80 participants

Calcaneal Angles And Postoperative Body Balance Following Internal Fixation

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-15

Start Date:

2026-05-10

Completion:

2028-01-15

Conditions

• Body Balnace and Calcaneal Fractures

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT07589179 | NOT_YET_RECRUITING | NA

68 participants

Evaluation of Occlusal Force and Masticatory Function in Children With Molar-Incisor Hypomineralization

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2026-05-11

Completion:

2026-10-20

Conditions

• Molar-Incisor Hypomineralization (MIH)
• Masticatory Performance
• Occlusal Analysis
• Chewing Function

Interventions

• PROCEDURE

No Results Yet

NCT07589153 | COMPLETED | NA

110 participants

Which Patinets Benefit More From Percutaneous Nephrolithotomy? A Location-Based Comparative Analysis of PCNL and RIRS for 1-2 cm Renal Stones

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2012-05-01

Completion:

2013-09-15

Conditions

• Kidney Calculi Nephrolithiasis Urolithiasis Renal Stone

Interventions

• DEVICE

No Results Yet

NCT07589140 | NOT_YET_RECRUITING | NA

124 participants

Influence of Alveolar Bone Drilling and Anatomical Position on Integration

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2026-04-30

Completion:

2028-01-31

Conditions

• Dental Implant
• Bone Grafting
• Immediate Dental Implant Placement

Interventions

• PROCEDURE
• DEVICE

No Results Yet

NCT07589127 | NOT_YET_RECRUITING | NA

70 participants

GENicular Nerve Block in KNEE Arthroplasty

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2026-06-01

Completion:

2028-06-01

Conditions

• Osteoarthritis (OA) of the Knee
• Total Knee Arthroplasty
• Genicular Nerve Block

Interventions

• PROCEDURE

No Results Yet

NCT07589114 | RECRUITING | NA

360 participants

REM Enhancement Sleep Technology for Well-being, Emotion, and Life Lift

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2025-11-15

Completion:

2026-12-31

Conditions

• Healthy Adult Participants

Interventions

• DEVICE

No Results Yet

NCT07589101 | NOT_YET_RECRUITING | NA

20 participants

5T4 Targeting Nanobody Probe for PET Imaging in Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2026-06-01

Completion:

2027-06-30

Conditions

• Lung Cancer
• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT07589088 | NOT_YET_RECRUITING | NA

126 participants

AI-GF-GNW on Prolonged Grief Reactions

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2026-05-25

Completion:

2027-05-31

Conditions

• Artificial Intelligence (AI)
• Prolonged Grief Symptoms
• Depression - Major Depressive Disorder
• Anxiety
• Disabilities

Interventions

• BEHAVIORAL

No Results Yet

NCT07589075 | COMPLETED | PHASE4

500 participants

Sodium-Glucose Co-Transporter-2 Inhibitors as Adjuvant Therapy With Letrozole in Induction of Ovulation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2023-10-20

Completion:

2024-07-01

Conditions

• Induction of Ovulation

Interventions

• DRUG

No Results Yet

NCT07589062 | NOT_YET_RECRUITING | NA

30 participants

Healthy Eating and Active Living for People Living With Multiple Sclerosis (HEAL MS): A Lifestyle Program for People With Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2026-04-15

Completion:

2027-11-15

Conditions

• Multiple Sclerosis (MS) - Relapsing-remitting
• Multiple Sclerosis

Interventions

• OTHER

No Results Yet

NCT07589049 | NOT_YET_RECRUITING | PHASE2

42 participants

Becotatug Vedotin Combined With Pucotenlimab as Neoadjuvant Therapy for Resectable Recurrent Head and Neck Squamous Cell Carcinoma After Progression on Immunotherapy: A Prospective Phase II Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2026-05-31

Completion:

2027-11-30

Conditions

• Head and Neck Squamous Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT07589023 | NOT_YET_RECRUITING

100 participants

A Retrospective Review: Outcomes of the REFLECT™ System for Idiopathic Scoliosis

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-15

Start Date:

2026-06-15

Completion:

2027-01-30

Conditions

• Idiopathic Scoliosis

Interventions

• DEVICE

No Results Yet

NCT07589010 | COMPLETED | NA

192 participants

Effectiveness of Peripheral Intravenous Line Securement With Splint in Neonates

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2025-10-01

Completion:

2026-03-31

Conditions

• Peripheral Intravenous Line

Interventions

• PROCEDURE

No Results Yet

NCT07588997 | RECRUITING | NA

18 participants

Early Motor-Cognitive Integrative Training on Cognitive and Motor Performance in Patients With Aneurysmal Subarachnoid Hemorrhage

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2025-11-23

Completion:

2027-08-31

Conditions

• Subarachnoid Aneurysm Hemorrhage

Interventions

• OTHER

No Results Yet

NCT07588984 | NOT_YET_RECRUITING

2310 participants

GLP-1 Medication & Behavioral Health Programs on Weight & Metabolic Outcomes: FLOURISH and THRIVE Prospective Cohort Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-15

Start Date:

2026-04-30

Completion:

2029-05-31

Conditions

• Obesity & Overweight
• Weight Loss
• Preventative Health
• Body Weight
• Cardiovascular Disease Risk Factor

Interventions

• DRUG
• BEHAVIORAL

No Results Yet

NCT07588971 | RECRUITING

2300 participants

Natural History and Prognosis of Pediatric Epilepsies With Different Etiology

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-15

Start Date:

2021-10-26

Completion:

2027-01-01

Conditions

• Pediatric Epilepsies

No Results Yet

NCT07588958 | ACTIVE_NOT_RECRUITING | NA

42 participants

Genicular Nerve Versus Adductor Canal Block for Postoperative Analgesia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2023-10-01

Completion:

2026-05-06

Conditions

• Postoperative Pain After Total Knee Arthroplasty

Interventions

• OTHER

No Results Yet