Clinical Trials

NCT04603196 | RECRUITING

800 participants

Prevalence and Impact of Obstructive Sleep Apnea in Multiple Sclerosis

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-11

Start Date:

2019-06-20

Completion:

2026-06-20

Conditions

• Multiple Sclerosis
• Obstructive Sleep Apnea

No Results Yet

NCT04597125 | ACTIVE_NOT_RECRUITING | PHASE4

654 participants

RADIANT: A Study of Radium-223 Dichloride (Xofigo) vs Enzalutamide or Abiraterone (ARPIs, Androgen Receptor Pathway Inhibitors) in Patients With Prostate Cancer That Has Spread to the Bones (mCRPC, Metastatic Castration-Resistant Prostate Cancer)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-11-09

Completion:

2025-11-21

Conditions

• Metastatic Castrate Resistant Prostate Cancer (mCRPC)

Interventions

• DRUG

No Results Yet

NCT04592315 | COMPLETED | PHASE1

46 participants

A Study to Assess the Safety, Tolerability and Pharmacokinetics of Lipovirtide in HIV-infected Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2021-01-23

Completion:

2023-05-02

Conditions

• HIV Infections

Interventions

• DRUG

No Results Yet

NCT04591496 | COMPLETED | NA

260 participants

The SmartFeeding4Kids: Study of a New Web-based Food Parenting Intervention

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2021-07-13

Completion:

2023-12-31

Conditions

• Parental Feeding Practices and Children's Healthy Diet

Interventions

• BEHAVIORAL

No Results Yet

NCT04590690 | RECRUITING | NA

28 participants

Gut Microbiome and Sex as Risk Factors for Kidney Stones After Bariatric Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-11-01

Completion:

2027-03-01

Conditions

• Bariatric Surgery Candidate

Interventions

• OTHER

No Results Yet

NCT04582695 | COMPLETED | NA

60 participants

Early Intervention Following Sexual Assault

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-12-15

Completion:

2026-02-23

Conditions

• Ptsd
• Alcohol Use Disorder
• Sexual Assault and Rape

Interventions

• BEHAVIORAL

No Results Yet

NCT04580134 | RECRUITING | PHASE4

524 participants

CLOZAPINE Response in Biotype-1

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-03-01

Completion:

2027-04-30

Conditions

• Schizophrenia
• Schizoaffective Disorder
• Bipolar 1 Disorder

Interventions

• DRUG

No Results Yet

NCT04571502 | TERMINATED | NA

42 participants

Integration of Health Information Technology and Promotion of Personhood in Family-Centered Dementia Care

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2025-02-07

Completion:

2025-09-25

Conditions

• Neurocognitive Disorders
• Alzheimer Disease
• Caregiver

Interventions

• OTHER

No Results Yet

NCT04571229 | AVAILABLE

Expanded Access Use of L-MTP-PE for the Treatment of Osteosarcoma

Study Type:

EXPANDED_ACCESS

Last Updated:

2026-05-11

Conditions

• Osteosarcoma

Interventions

• DRUG

No Results Yet

NCT04569097 | COMPLETED | NA

227 participants

Novel Pharyngeal Metrics to Predict Dysphagia Outcomes

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2021-06-28

Completion:

2024-09-30

Conditions

• Dysphagia
• Swallowing Disorders

Interventions

• OTHER

Results Available

NCT04560140 | RECRUITING | NA

208 participants

Promoting Community Reintegration for Young Adults With Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2021-09-01

Completion:

2027-12-31

Conditions

• Stroke

Interventions

• BEHAVIORAL

No Results Yet

NCT04542148 | ACTIVE_NOT_RECRUITING | PHASE2

120 participants

Glycemic Control After Antenatal Corticosteroids in Women With Pregestational and Gestational Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-02-10

Completion:

2025-11-30

Conditions

• Diabetes Mellitus, Type 2
• Preterm Birth
• Pregnancy, High Risk
• Diabetes, Gestational

Interventions

• DRUG
• DEVICE

No Results Yet

NCT04505826 | COMPLETED | PHASE1/PHASE2

153 participants

A Dose Escalation/Expansion Study of Oral OP-1250 in Subjects With Advanced and/or Metastatic HR+, HER2- Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-08-13

Completion:

2024-07-30

Conditions

• Hormone Receptor Positive Breast Carcinoma
• HER2-negative Breast Cancer

Interventions

• DRUG

Results Available

NCT04502602 | ACTIVE_NOT_RECRUITING | PHASE1

18 participants

Niraparib and Neratinib in Advanced Solid Tumors With Expansion Cohort in Advanced Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-08-24

Completion:

2024-10-30

Conditions

• Advanced Solid Tumor
• Ovarian Cancer

Interventions

• DRUG

No Results Yet

NCT04502316 | ACTIVE_NOT_RECRUITING

5000 participants

Real-World Experience - Barostim™ Advancing the Level of Clinical Evidence (REBALANCE Registry)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-11

Start Date:

2020-06-26

Completion:

2028-06-30

Conditions

• Heart Failure

Interventions

• DEVICE

No Results Yet

NCT04497844 | ACTIVE_NOT_RECRUITING | PHASE3

696 participants

A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants With Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-Mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-09-23

Completion:

2025-01-07

Conditions

• Metastatic Castration-sensitive Prostate Cancer

Interventions

• DRUG

Results Available

NCT04490915 | ACTIVE_NOT_RECRUITING | PHASE3

182 participants

Global Safety and Efficacy Registration Study of Crinecerfont for Congenital Adrenal Hyperplasia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-12-16

Completion:

2023-07-19

Conditions

• Congenital Adrenal Hyperplasia

Interventions

• DRUG

Results Available

NCT04486755 | ACTIVE_NOT_RECRUITING | PHASE1

18 participants

Hypofractionated Accelerated Pelvic Nodal Radiotherapy (GCC 2048)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-11-19

Completion:

2026-08-31

Conditions

• Prostate Cancer
• Prostate Adenocarcinoma

Interventions

• RADIATION

No Results Yet

NCT04477577 | COMPLETED | NA

657 participants

First Heroes: Engaging Fathers in the First 1000 Days

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-08-04

Completion:

2023-11-30

Conditions

• Obesity, Childhood
• Overweight and Obesity
• Social Determinants of Health
• Physical Activity
• Feeding Behavior
• Sleep
• Diet Habit

Interventions

• BEHAVIORAL

Results Available

NCT04477330 | RECRUITING | NA

100 participants

Cortical Priming to Optimize Gait Rehabilitation in Stroke: a Renewal

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-09-01

Completion:

2026-12-31

Conditions

• Stroke

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT04464759 | RECRUITING | PHASE1/PHASE2

94 participants

A Study of Nivolumab and Hydroxychloroquine or Nivolumab/Ipilimumab and Hydroxychloroquine in Advanced Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-10-21

Completion:

2027-01-06

Conditions

• Melanoma

Interventions

• DRUG

No Results Yet

NCT04453072 | RECRUITING | NA

20 participants

A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-07-01

Completion:

2026-12-31

Conditions

• Obesity
• Malignant Neoplasm

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT04436965 | RECRUITING | PHASE3

266 participants

Effect of Standard Nutrition Therapy on Nutritional Status and Prognosis in Locoregionally Advanced Nasopharyngeal Carcinoma Patients With Malnutrition

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2021-08-16

Completion:

2026-12-31

Conditions

• Nasopharyngeal Carcinoma
• Nutrition Therapy

Interventions

• OTHER
• DRUG
• RADIATION

No Results Yet

NCT04427241 | RECRUITING | PHASE4

12 participants

Efficacy and Safety of Cerebrolysin on Prolonged Disorders of Consciousness

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2023-06-01

Completion:

2026-09-30

Conditions

• Disorder of Consciousness
• Hemorrhagic Stroke

Interventions

• DRUG

No Results Yet

NCT04389632 | RECRUITING | PHASE1

1006 participants

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-06-08

Completion:

2027-06-16

Conditions

• Carcinoma, Non-Small Cell Lung
• Squamous Cell Carcinoma of Head and Neck
• HER2 Negative Breast Neoplasms
• Esophageal Squamous Cell Carcinoma
• Esophageal Adenocarcinoma
• Gastroesophageal Junction Adenocarcinoma
• Ovarian Neoplasms
• Cutaneous Squamous Cell Cancer
• Exocrine Pancreatic Adenocarcinoma
• Urinary Bladder Neoplasms
• Uterine Cervical Neoplasms
• Stomach Neoplasms

Interventions

• DRUG

No Results Yet

NCT04385615 | WITHDRAWN | NA

0 participants

Fasting Mimicking Diet and Beige/Brown Adipose Tissue in Humans

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2021-02-28

Completion:

2021-12-31

Conditions

• Obesity

Interventions

• OTHER

No Results Yet

NCT04384770 | ACTIVE_NOT_RECRUITING

179 participants

CT-guided Stereotactic Body Radiation Therapy and MRI-guided Stereotactic Body Radiation Therapy for Prostate Cancer, MIRAGE Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-11

Start Date:

2020-05-12

Completion:

2027-04-01

Conditions

• Prostate Adenocarcinoma

Interventions

• RADIATION
• OTHER

No Results Yet

NCT04380740 | RECRUITING | PHASE2

160 participants

Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-03-30

Completion:

2027-05-31

Conditions

• Graft Vs Host Disease

Interventions

• DRUG

No Results Yet

NCT04373642 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

"QUAD SHOT" Radiotherapy With Pembrolizumab in Patients With Recurrent Head & Neck Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-12-23

Completion:

2025-10-14

Conditions

• Head and Neck Cancer

Interventions

• DRUG

No Results Yet

NCT04358601 | ACTIVE_NOT_RECRUITING | NA

60 participants

All-poly Versus Metal-backed

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2014-11-01

Completion:

2017-09-17

Conditions

• Osteoarthritis

Interventions

• DEVICE

No Results Yet

NCT04358276 | ACTIVE_NOT_RECRUITING | NA

840 participants

Technology-Enabled Activation of Skin Cancer Screening for Stem Cell Transplant Survivors and Their Primary Care Providers, TEACH Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-10-30

Completion:

2026-07-30

Conditions

• Skin Carcinoma

Interventions

• OTHER
• DEVICE

No Results Yet

NCT04348747 | RECRUITING | PHASE2

23 participants

Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-12-19

Completion:

2027-06-15

Conditions

• Anatomic Stage IV Breast Cancer AJCC v8
• Metastatic Malignant Neoplasm in the Brain
• Metastatic Triple-Negative Breast Carcinoma
• Prognostic Stage IV Breast Cancer AJCC v8

Interventions

• BIOLOGICAL

No Results Yet

NCT04337177 | ACTIVE_NOT_RECRUITING | PHASE1

20 participants

Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2021-10-25

Completion:

2026-06-30

Conditions

• Solid Tumors
• Neuroblastoma
• Rhabdomyosarcoma
• Ewing Sarcoma
• Hepatoblastoma
• Medulloblastoma

Interventions

• DRUG

No Results Yet

NCT04336085 | COMPLETED | NA

60 participants

Comparison of Ultrasound Guided Caudal Block and Ultrasound Guided Pericapsular Nerve Group Block for Pediatric Hip Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-04-15

Completion:

2024-04-15

Conditions

• Post Operative Pain After Pediatric Hip Surgery

Interventions

• PROCEDURE

No Results Yet

NCT04310930 | RECRUITING | PHASE2/PHASE3

300 participants

Finding the Optimal Regimen for Mycobacterium Abscessus Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-03-02

Completion:

2029-06-30

Conditions

• Pulmonary Disease Due to Mycobacteria (Diagnosis)

Interventions

• DRUG

No Results Yet

NCT04308473 | COMPLETED | NA

46 participants

Analysis of MicroBial Metabolites After Eating Refined Food

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-09-01

Completion:

2023-02-28

Conditions

• Dietary Habits

Interventions

• OTHER

No Results Yet

NCT04297020 | RECRUITING

120 participants

Brain Health in Breast Cancer Survivors

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-11

Start Date:

2020-03-11

Completion:

2027-03-15

Conditions

• Cognitive Impairment
• Cognitive Function

No Results Yet

NCT04273139 | ACTIVE_NOT_RECRUITING | PHASE2

45 participants

Ibrutinib + Venetoclax in Untreated WM

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-07-09

Completion:

2022-06-06

Conditions

• Waldenstrom Macroglobulinemia
• MYD88 Gene Mutation

Interventions

• DRUG

Results Available

NCT04262154 | ACTIVE_NOT_RECRUITING | PHASE2

28 participants

Study of Abiraterone Acetate or Enzalutamide, Atezolizumab, GnRH Analog and Radiation Therapy in Men With Newly Diagnosed Hormone-sensitive Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-03-03

Completion:

2025-07-07

Conditions

• Metastatic Prostate Cancer

Interventions

• DRUG
• RADIATION
• OTHER

Results Available

NCT04251533 | TERMINATED | PHASE3

137 participants

Study Assessing the Efficacy and Safety of Alpelisib + Nab-paclitaxel in Subjects With Advanced TNBC Who Carry Either a PIK3CA Mutation or Have PTEN Loss

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-06-08

Completion:

2023-05-31

Conditions

• Triple Negative Breast Neoplasms

Interventions

• DRUG

Results Available