Clinical Trials Updated in 2025

NCT07283107 | ENROLLING_BY_INVITATION | NA

8910 participants

Trial to Evaluate the Impact of Various Behavioural Interventions to Increase Mammography Uptake Among Singaporean Women

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-11-17
Completion:: 2026-12-31

Conditions

This Study Evaluates Interventions to Increase Surveillance Mammography Uptake for Early Breast Cancer Detection Among Singaporean Women

Interventions

BEHAVIORAL

No Results Yet

NCT07282392 | RECRUITING | NA

30 participants

Helping Lupus Patients Manage Fibromyalgia Symptoms Through Emotional Awareness and Expression Therapy (EAET)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-12-01
Completion:: 2028-10-15

Conditions

Lupus
Fibromyalgia (FM)
Chronic Widespread Pain

Interventions

BEHAVIORAL

No Results Yet

NCT07279987 | NOT_YET_RECRUITING | NA

162 participants

Comparison of RA-IVL and RA-SHP in Calcified Coronary Lesions

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2026-01-01
Completion:: 2027-12-31

Conditions

Vascular Calcification

Interventions

DEVICE

No Results Yet

NCT07279792 | COMPLETED | PHASE2/PHASE3

150 participants

Implications of Post-Operative Irrigation Fluid's Osmolarity on the Recurrence of Non-Muscle Invasive Bladder Cancer Following Transurethral Resection

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-10-01
Completion:: 2025-08-01

Conditions

Bladder (Urothelial, Transitional Cell) Cancer
Nonmuscle Invasive Bladder Cancer
Irrigation
Hypertonic Saline
Normal Saline
Distilled Water

Interventions

DRUG

No Results Yet

NCT07276945 | NOT_YET_RECRUITING

300 participants

Individualized Early Diagnosis and Treatment System of Gestational Diabetes Mellitus (GDM) Based on New Continuous Glucose Monitoring (CGM) Technology

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-12-10
Completion:: 2028-07-01

Conditions

Gestational Diabetes

Interventions

OTHER

No Results Yet

NCT07276230 | NOT_YET_RECRUITING | NA

27 participants

Quality of Life Assessment of Caregivers of Patients With Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2026-02-01
Completion:: 2027-05-01

Conditions

Caregivers of Patients With Multiple Myeloma

Interventions

OTHER

No Results Yet

NCT07265622 | RECRUITING | PHASE1/PHASE2

200 participants

First-in-human Study of 7MW4911 in Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-11-12
Completion:: 2027-07-31

Conditions

Solid Tumors

Interventions

DRUG

No Results Yet

NCT07261020 | COMPLETED | NA

40 participants

The Effectiveness of Pilates in Women With Lumbar Disc Herniation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-01-05
Completion:: 2024-03-15

Conditions

Disc Herniation
Kinesiophobia
Low Back Pain

Interventions

OTHER

No Results Yet

NCT07253610 | COMPLETED | NA

56 participants

Effect of Bilateral Rectointercostal Fascial Plane Block on Postoperative Pain After Laparoscopic Sleeve Gastrectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-11-01
Completion:: 2025-12-21

Conditions

Obesity, Morbid
Pain, Postoperative
Laparoscopic Sleeve Gastrectomy (LSG)
Opioid Use

Interventions

OTHER

No Results Yet

NCT07252193 | COMPLETED | NA

120 participants

Generative AI-Based Simulation for Diagnostic Communication in Type 2 Diabetes (DIALOGUE-DM2)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-09-22
Completion:: 2025-12-18

Conditions

Type 2 Diabetes Mellitus
Medical Education
Diagnostic Communication
Artificial Intelligence Simulation

Interventions

BEHAVIORAL

No Results Yet

NCT07228858 | COMPLETED | NA

170 participants

Uterine Scar Resection During Repeat Cesarean Delivery to Prevent Uterine Niche Formation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-02-09
Completion:: 2025-05-30

Conditions

Cesarean Section Complications
Scar Niche
Scarred Uterus

Interventions

PROCEDURE
DIAGNOSTIC_TEST

No Results Yet

NCT07212946 | COMPLETED | PHASE2

22 participants

Ayahuasca and Esketamine for Major Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-10-30
Completion:: 2024-10-30

Conditions

Major Depression Severe

Interventions

DRUG

No Results Yet

NCT07211776 | RECRUITING | PHASE3

99 participants

A Study to Assess the Efficacy and Safety of ZL-1109 in Chinese Participants With Active Thyroid Eye Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-12-05
Completion:: 2027-03-14

Conditions

Thyroid Eye Disease (TED)

Interventions

DRUG

No Results Yet

NCT07175623 | COMPLETED | NA

60 participants

Methylprednisolone vs Dexamethasone Interaction With Sugammadex in Pediatric Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-09-16
Completion:: 2025-12-20

Conditions

Neuromuscular Block, Residual
Pain Management
Postoperative Nausea

Interventions

DRUG

No Results Yet

NCT07172776 | NOT_YET_RECRUITING | NA

50 participants

A Community Engagement Approach to Improving Communication With Black Men About Oral and Pharyngeal Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2026-01-01
Completion:: 2026-12-31

Conditions

Oral Cancers

Interventions

BEHAVIORAL

No Results Yet

NCT07166757 | RECRUITING | PHASE1/PHASE2

90 participants

Clinical Study to Evaluate XS411 in Treatment of Early-onset Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-09-22
Completion:: 2028-03-30

Conditions

Parkinson Disease (PD)

Interventions

DRUG

No Results Yet

NCT07165067 | RECRUITING | PHASE1

36 participants

A Study of AP601 in Patients With Locally Unresectable Advanced or Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2026-01-21
Completion:: 2027-12-27

Conditions

Solid Tumours

Interventions

DRUG

No Results Yet

NCT07162922 | COMPLETED | NA

76 participants

Optic Nerve Sheath Diameter Changes in Laparoscopic Cholecystectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-09-17
Completion:: 2025-12-21

Conditions

Increased Intracranial Pressure Disorders
Perioperative Complication
Pneumoperitoneum

Interventions

OTHER

No Results Yet

NCT07157124 | RECRUITING | NA

62 participants

Examining the Effectiveness of Dynamic Visual Noise (DVN) for Reducing Alcohol Cravings and Consumption in College Students

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-09-22
Completion:: 2026-09-30

Conditions

Craving
Alcohol Drinking

Interventions

OTHER

No Results Yet

NCT07154667 | RECRUITING | NA

30 participants

Evaluation of the Auryzon™ EAR 2.0 System in Ear Reconstruction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-10-01
Completion:: 2030-12-31

Conditions

Microtia, Congenital
Microtia
Microtia-Anotia
Ear Deformities, Acquired
Ear Deformity External
Ear Malformation
Ear Cartilage

Interventions

PROCEDURE

No Results Yet

NCT07124975 | ENROLLING_BY_INVITATION | NA

186 participants

Impact of Comparing Treatment Status With Other CPAP Users

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-10-01
Completion:: 2027-12-31

Conditions

Sleep Apnea
Obstructive Sleep Apnea

Interventions

BEHAVIORAL

No Results Yet

NCT07122219 | RECRUITING | NA

548 participants

Enhancing Uptake of Needle and Syringe Programs in Canadian Federal Prisons

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-10-01
Completion:: 2028-02-29

Conditions

HIV
Hepatitis C Virus (HCV)

Interventions

BEHAVIORAL

No Results Yet

NCT07102056 | NOT_YET_RECRUITING

152 participants

18F-AlF-NOTA-Octreotide PET in Neuroendocrine Neoplasms

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2026-01-01
Completion:: 2027-06-03

Conditions

Neuroendocrine Tumors

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07100210 | RECRUITING | PHASE1

6 participants

A Clinical Trial Evaluating IL-22BP/LNP Compound in Refractory Malignant Solid Tumors for Safety, Tolerability and Activity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-01-20
Completion:: 2026-02-20

Conditions

Refractory Malignant Solid Tumors
mRNA Vaccine
Interleukin

Interventions

BIOLOGICAL

No Results Yet

NCT07100067 | RECRUITING | NA

35 participants

LCAR-F33S in Treatment of Relapsed/Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-09-16
Completion:: 2028-02-20

Conditions

Relapsed/Refractory Multiple Myeloma(MM)

Interventions

BIOLOGICAL

No Results Yet

NCT07094581 | RECRUITING

72 participants

Evaluation of the Effect of Adenoid Hypertrophy on the Masseter Muscle in Children: A Comparative Ultrasonographic Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-07-20
Completion:: 2026-02-09

Conditions

Adenoid Hypertrophy
Masseter Muscle
Malocclusion

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07092384 | COMPLETED | NA

265 participants

Effect of Remifentanil on Pruritus and Paresthesia of Fospropofol Disodium Anesthesia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-07-30
Completion:: 2025-11-30

Conditions

Remifentanil
Adverse Effects

Interventions

DRUG

No Results Yet

NCT07086820 | RECRUITING | NA

647 participants

Window Prophylaxis for Pediatric Tuberculosis Prevention Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-10-27
Completion:: 2028-05-31

Conditions

Tuberculosis Infection
Household Contacts
Children
Adolescent
Tuberculosis Infection, Latent
Tuberculosis

Interventions

DRUG

No Results Yet

NCT07070791 | RECRUITING | NA

40 participants

Combined Upper Extremity Resistance and Aerobic Exercise Training in Patients With Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-07-08
Completion:: 2026-05-01

Conditions

Breast Cancer
Upper Extremity
Resistance Exercise
Aerobic Exercise

Interventions

OTHER

No Results Yet

NCT07070778 | RECRUITING | NA

18 participants

Arterial Stiffness in Individuals With Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-07-08
Completion:: 2026-11-01

Conditions

Aerobic Exercise
Breast Cancer
Arterial Stiffness

Interventions

OTHER

No Results Yet

NCT07063173 | RECRUITING | NA

15 participants

Bioavailability of Ration Items Containing Tart Cherry Extract

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-06-14
Completion:: 2025-12-31

Conditions

Bioavailability

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07058454 | RECRUITING

5000 participants

Multicenter Prospective Observational Study of Cardiotoxicity in Patients Receiving Targeted Cancer Therapies

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-09-01
Completion:: 2027-09-01

Conditions

Cancer;Cardiovascular;Adverse Events
Cancer

No Results Yet

NCT07050485 | ENROLLING_BY_INVITATION | NA

30 participants

Postbiotics for Mitigation of Postoperative Dysbiosis in Gastrointestinal Cancer Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-07-15
Completion:: 2026-04-30

Conditions

Colon Cancer
Gastrointestinal Cancer

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07050277 | RECRUITING | PHASE3

50 participants

Post-Operative Urinary Retention on Revision Knee Arthroplasty: the Role of Intrathecal Morphine

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-06-24
Completion:: 2027-07-01

Conditions

Arthroplasties, Knee Replacement
Nerve Block
Urinary Retention Postoperative
Anesthesia, Spinal

Interventions

DRUG

No Results Yet

NCT07024693 | RECRUITING | PHASE2

28 participants

DT-168 in Keratoplasty Patients With Fuchs Endothelial Corneal Dystrophy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-07-30
Completion:: 2026-09-30

Conditions

Fuchs Endothelial Corneal Dystrophy
Fuchs

Interventions

DRUG

No Results Yet

NCT07023107 | COMPLETED | PHASE4

60 participants

NLR and PLR Levels Following PENG Block in Hip Arthroplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-06-16
Completion:: 2025-12-09

Conditions

Hip Arthropathy
Hip Osteoarthritis
Hip Pain Chronic

Interventions

DRUG

No Results Yet

NCT07008001 | RECRUITING | NA

175 participants

Assessment of DOT Spectacles in Chinese Children Extension

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-08-01
Completion:: 2026-09-30

Conditions

Juvenile Myopia
Myopia

Interventions

DEVICE

No Results Yet

NCT06996548 | COMPLETED

120 participants

Sarcopenia and Paclitaxel-Induced Neuropathy in Early Stage Breast Cancer (Neuro-Sarc)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-11-01
Completion:: 2025-05-06

Conditions

Sarcopenia
Paclitaxel Induced Neuropathy
Breast Carcinoma

No Results Yet

NCT06974630 | COMPLETED | NA

40 participants

Cervical Erector Spinae Plane Block vs Cervical Plexus Block in Controlling Acute Postoperative Pain After Thyroidectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-05-15
Completion:: 2025-11-30

Conditions

Cervical
Erector Spinae Plane Block
Cervical Plexus Block
Postoperative Pain
Thyroidectomy

Interventions

OTHER

No Results Yet

NCT06973447 | COMPLETED | NA

30 participants

Combined ASSNB and ICBPB vs CCBPB in Shoulder Arthroscopy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-01-30
Completion:: 2025-09-30

Conditions

Postoperative Pain
Shoulder Arthroscopy

Interventions

PROCEDURE

No Results Yet