Clinical Trials

NCT05217927 | COMPLETED | PHASE4

1415 participants

Efficacy and Safety Study of Rimegepant in Episodic Migraine Prevention With Multiple Dosing Regimens

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2022-03-04

Completion:

2024-10-22

Conditions

• Migraine

Interventions

• DRUG

Results Available

NCT05211830 | COMPLETED | PHASE1/PHASE2

9 participants

A Study to Evaluate Topically Applied SXR1096 Cream in Patients With Netherton Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2021-12-07

Completion:

2025-06-10

Conditions

• Netherton Syndrome

Interventions

• DRUG

No Results Yet

NCT05195060 | COMPLETED

1178 participants

TURN-COVID Biobank: The Dutch Cohort Study for the Evaluation of the Use of Neutralizing Monoclonal Antibodies and Other Antiviral Agents Against SARS-CoV-2

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-16

Start Date:

2021-12-14

Completion:

2025-09-01

Conditions

• COVID-19

Interventions

• DRUG

No Results Yet

NCT05165433 | COMPLETED | PHASE1

14 participants

Study of NG-350A Plus Pembrolizumab in Metastatic or Advanced Epithelial Tumours (FORTIFY)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2022-04-13

Completion:

2025-08-29

Conditions

• Epithelial Tumor
• Metastatic Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT05161598 | NO_LONGER_AVAILABLE

Pre-approval Access Single Patient Request for Teclistamab (JNJ-64007957)

Study Type:

EXPANDED_ACCESS

Last Updated:

2025-12-16

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT05133492 | ACTIVE_NOT_RECRUITING | NA

46 participants

First In Human Study for Small to Medium-sized Abdominal Aortic Aneurysm (AAA)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2019-06-24

Completion:

2026-12-31

Conditions

• Abdominal Aortic Aneurysm
• AAA
• Dilation Aorta

Interventions

• DEVICE

No Results Yet

NCT05120635 | RECRUITING | NA

80 participants

Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2021-10-01

Completion:

2026-06-30

Conditions

• Fear
• GAD
• Emotional Memory
• PTSD

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT05117515 | COMPLETED

200 participants

Retrospective Study of the Uni-Graft® K DV Patch in the Clinical Routine

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-16

Start Date:

2022-04-27

Completion:

2024-11-27

Conditions

• Femoral Artery Stenosis
• Iliac Artery Stenosis
• Carotid Artery Stenosis

Interventions

• DEVICE

No Results Yet

NCT05116943 | RECRUITING

100 participants

Biospecimen Biorepository for the Study of ALS, ALS-FTD and Similar Neurodegenerative Disorders

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-16

Start Date:

2013-08-19

Completion:

2030-01-31

Conditions

• Amyotrophic Lateral Sclerosis

No Results Yet

NCT05097274 | RECRUITING

50 participants

The GENPET Study - An Imaging Study of FCH-PET-CT in Men With Prostate Cancer and a DNA Repair Gene Mutation.

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-16

Start Date:

2015-10-15

Completion:

2027-12-31

Conditions

• Prostate Cancer
• BRCA Mutation
• Mismatch Repair Gene Mutation
• ATM Gene Mutation
• HOXB13 Germline Mutation
• CHEK2 Gene Mutation
• PALB2 Gene Mutation

Interventions

• OTHER

No Results Yet

NCT05077332 | COMPLETED | PHASE2

4 participants

LEAP-CT for Treatment of COVID-19 Patients (Master Protocol)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2021-12-29

Completion:

2025-11-10

Conditions

• 2019 Novel Coronavirus Disease
• 2019 Novel Coronavirus Infection
• 2019-nCoV Disease
• 2019-nCoV Infection
• COVID-19 Pandemic
• COVID-19 Virus Disease
• COVID-19 Virus Infection
• Covid19
• Coronavirus Disease 2019
• SARS-CoV-2 Infection
• SARS-CoV-2 Acute Respiratory Disease
• COVID-19

Interventions

• DRUG
• OTHER

No Results Yet

NCT05065580 | COMPLETED | NA

25 participants

OMT as an Adjunctive Treatment in MDD

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2021-03-12

Completion:

2023-03-23

Conditions

• Major Depressive Disorder

Interventions

• PROCEDURE

No Results Yet

NCT05032261 | COMPLETED

100 participants

ICU Norepinephrine Load

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-16

Start Date:

2021-09-01

Completion:

2024-12-31

Conditions

• Circulatory Collapse and Shock

Interventions

• DRUG

No Results Yet

NCT05001347 | COMPLETED | PHASE2

25 participants

A Clinical Study of TJ004309 With Atezolizumab (TECENTRIQ®) in Patients With Ovarian Cancer and Selected Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2021-11-02

Completion:

2023-02-08

Conditions

• Ovarian Cancer
• Head and Neck Cancer
• Non Small Cell Lung Cancer
• Gastrointestinal Cancer
• Triple Negative Breast Cancer
• Ovarian Carcinoma

Interventions

• DRUG

Results Available

NCT05000866 | ACTIVE_NOT_RECRUITING | NA

484 participants

Expanding the Potential of Couples HIV Testing: Adjunct Modules to Reduce Drug Use Among Vulnerable Male Couples

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2021-10-13

Completion:

2026-05-31

Conditions

• Substance Use
• HIV Infections

Interventions

• BEHAVIORAL

No Results Yet

NCT04987489 | COMPLETED | PHASE2

53 participants

A Study of Etavopivat in Patients With Thalassemia or Sickle Cell Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2022-03-28

Completion:

2025-09-03

Conditions

• Sickle Cell Disease
• Thalassemia

Interventions

• DRUG

No Results Yet

NCT04985695 | RECRUITING | NA

110 participants

Influence of Analgesic Technique on Post Operative Rehabilitation After Median Laparotomy

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2021-10-11

Completion:

2028-10-10

Conditions

• Laparotomy

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04973137 | TERMINATED | PHASE3

208 participants

A Study to Evaluate the Efficacy and Safety of Birtamimab in Mayo Stage IV Patients With AL Amyloidosis

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2021-08-30

Completion:

2025-04-02

Conditions

• Light Chain (AL) Amyloidosis

Interventions

• DRUG
• OTHER

Results Available

NCT04948866 | COMPLETED | NA

884 participants

Palliative Care for Persons With Late-stage Alzheimer's and Related Dementias and Their Caregivers

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2021-07-26

Completion:

2025-02-01

Conditions

• Dementia
• Dementia, Vascular
• Dementia With Lewy Bodies
• Dementia Frontal
• Dementia, Mixed
• Dementia Alzheimers
• Alzheimer Disease
• Dementia Severe

Interventions

• BEHAVIORAL

Results Available

NCT04858009 | RECRUITING | PHASE2

40 participants

Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Pancreatic Cancer and Peritoneal Metastasis

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2024-02-15

Completion:

2029-07-31

Conditions

• Metastatic Pancreatic Carcinoma
• Stage IV Pancreatic Cancer AJCC v8
• Metastatic Malignant Neoplasm in the Peritoneum

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04799860 | COMPLETED | NA

12000 participants

Act in Time -Implementation of Health Promotive Work-way in Primary Care Setting (AcTi)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2021-03-30

Completion:

2024-12-31

Conditions

• Health Knowledge, Attitudes, Practice

Interventions

• BEHAVIORAL

No Results Yet

NCT04779216 | COMPLETED | PHASE3

30 participants

Effects of Romosozumab on Bone Density in Women With Anorexia Nervosa

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2021-09-20

Completion:

2024-10-24

Conditions

• Bone Density, Low
• Bone Loss
• Anorexia Nervosa
• Eating Disorders

Interventions

• DRUG

Results Available

NCT04765709 | TERMINATED | PHASE2

10 participants

Durvalumab and Chemotherapy Induction Followed by Durvalumab and Radiotherapy in Large Volume Stage III NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2021-09-24

Completion:

2025-01-30

Conditions

• Non-small Cell Lung Cancer Stage III

Interventions

• COMBINATION_PRODUCT
• BIOLOGICAL

No Results Yet

NCT04763317 | RECRUITING

3000 participants

Precision Medicine in the Prostate Cancer Care Pathway

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-16

Start Date:

2019-02-14

Completion:

2029-12-31

Conditions

• Prostate Cancer
• Genetic Predisposition

Interventions

• GENETIC

No Results Yet

NCT04722341 | RECRUITING | NA

175 participants

Time-Restricted Eating and Cancer: Clinical Outcomes, Mechanisms, and Moderators

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2022-01-01

Completion:

2026-06-30

Conditions

• Colorectal Cancer
• Breast Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT04707937 | COMPLETED | NA

150 participants

Evaluation of a Brachytherapy Discharge Education Program to Improve Patient Care

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2020-08-19

Completion:

2025-12-05

Conditions

• Gynecologic Cancer

Interventions

• OTHER

No Results Yet

NCT04702802 | COMPLETED | NA

36 participants

Study to Evaluate the Safety of the Viscoelastic Substance PRO-149, Compared to Healon® EndoCoat.

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2021-09-07

Completion:

2021-10-29

Conditions

• Age-related Cataract
• Phacoemulsification

Interventions

• DEVICE

Results Available

NCT04692597 | TERMINATED | NA

83 participants

Low Level Laser Therapy (LLLT) for the Treatment of Hand Osteoarthritis.

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2021-03-02

Completion:

2025-12-09

Conditions

• Low Level Laser Therapy
• Osteoarthritis
• Family Medicine
• Pain Management
• Integrative Medicine

Interventions

• DEVICE

No Results Yet

NCT04683848 | COMPLETED | PHASE2

72 participants

Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2021-08-27

Completion:

2024-12-24

Conditions

• Spinal Cord Injury

Interventions

• BIOLOGICAL

No Results Yet

NCT04634812 | COMPLETED | PHASE1

7 participants

Mass Balance Study of KBP-5074 in Healthy Male Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2020-12-03

Completion:

2020-12-23

Conditions

• Healthy

Interventions

• DRUG

No Results Yet

NCT04606537 | COMPLETED | PHASE1

24 participants

Drug to Drug Interaction Study of KBP-5074 in Healthy Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2020-10-24

Completion:

2020-11-30

Conditions

• Healthy
• Drug Drug Interaction

Interventions

• DRUG

No Results Yet

NCT04594369 | COMPLETED | PHASE3

1767 participants

A Study to Assess the Efficacy, Safety, and Tolerability of Brensocatib in Participants With Non-Cystic Fibrosis Bronchiectasis

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2020-12-01

Completion:

2024-10-28

Conditions

• Non-Cystic Fibrosis Bronchiectasis

Interventions

• DRUG

Results Available

NCT04577911 | RECRUITING

248 participants

How is Social Connection Represented in the Brain?

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-16

Start Date:

2021-04-01

Completion:

2026-11-30

Conditions

• Loneliness

Interventions

• OTHER

No Results Yet

NCT04575740 | COMPLETED | NA

209 participants

Phenotyping Mechanistic Pathways for Adverse Health Outcomes in Sleep Apnea

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2020-09-10

Completion:

2025-06-30

Conditions

• Sleep Apnea

Interventions

• DEVICE

No Results Yet

NCT04565925 | RECRUITING | PHASE2

24 participants

Sildenafil for Treatment of Urinary Incontinence in Patients With Spinal Cord Injuries

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2021-07-07

Completion:

2026-12-01

Conditions

• Spinal Cord Injuries
• Urinary Incontinence

Interventions

• DRUG

No Results Yet

NCT04534699 | COMPLETED | PHASE1

12 participants

Pharmacokinetics of KBP-5074 in Patients With Moderate Hepatic Impairment

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2020-08-27

Completion:

2020-11-19

Conditions

• Moderate Hepatic Impairment
• Healthy

Interventions

• DRUG

No Results Yet

NCT04491045 | COMPLETED | NA

1382 participants

Implementation Strategies for Task-Shifting Depression Care Depression Care in Vietnam

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2021-12-01

Completion:

2025-04-30

Conditions

• Depression

Interventions

• OTHER

No Results Yet

NCT04445064 | TERMINATED | PHASE2

17 participants

Activity and Safety of Peptide-based Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck.

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2020-08-14

Completion:

2024-06-08

Conditions

• Oropharynx Squamous Cell Carcinoma
• Larynx Squamous Cell Carcinoma
• Hypopharynx Squamous Cell Carcinoma
• Oral Cavity Squamous Cell Carcinoma

Interventions

• BIOLOGICAL

No Results Yet

NCT04427293 | RECRUITING | PHASE1

12 participants

Preoperative Lenvatinib Plus Pembrolizumab in Early-Stage Triple-Negative Breast Cancer (TNBC)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-16

Start Date:

2020-07-09

Completion:

2026-07-31

Conditions

• Triple Negative Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04308928 | COMPLETED

332 participants

Evaluation of New Biomarker-based Approaches for Improving the Diagnosis of Childhood Tuberculous Meningitis

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-16

Start Date:

2020-04-01

Completion:

2024-10-31

Conditions

• Tuberculous Meningitis

No Results Yet