Clinical Trials Updated in 2025

NCT07281846 | RECRUITING | NA

164 participants

TIPS With or Without BCAA

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-11-15
Completion:: 2027-11-15

Conditions

BCAA
Cirrhosis
Portal Hypertension Related to Cirrhosis
Sarcopenia
Transjugular Intrahepatic Portosystemic Shunt

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07281820 | RECRUITING | NA

30 participants

FRAME - Implementation of a PRO Measure to Inform Patient-Centered Survivorship Care in Oncology Outpatient Visits

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-03-01
Completion:: 2026-12-31

Conditions

Cancer
Late Effects

Interventions

BEHAVIORAL

No Results Yet

NCT07281807 | NOT_YET_RECRUITING | PHASE4

60 participants

Comparison of the Pain Levels of Single-Dose Premedication With Piroxicam and Prednisolone on Post-Endodontic Pain in Single-Visit Root Canal Treatment of Premolars

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2026-01-01
Completion:: 2026-12-31

Conditions

Irreversible Pulpitis With Apical Periodontitis
Symptomatic Apical Periodontitis

Interventions

DRUG

No Results Yet

NCT07281742 | RECRUITING | NA

30 participants

Amblyopia Treatment for Children Aged 8 to 12 Years

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-01-07
Completion:: 2027-12-31

Conditions

Amblyopia

Interventions

DEVICE

No Results Yet

NCT07281729 | ENROLLING_BY_INVITATION

25000 participants

Investigation on Risk Factors for Suicide Among Chinese Patients With Mood Disorders

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-08-01
Completion:: 2026-06-30

Conditions

Bipolar Disorder；Major Depressive Disorder；Mood Disorders

No Results Yet

NCT07281690 | COMPLETED | PHASE3

20 participants

Enhancing Skin Rejuvenation Using Laser and Exosomes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-03-01
Completion:: 2025-07-17

Conditions

Laser Therapy
Exosomes

Interventions

DEVICE
BIOLOGICAL

No Results Yet

NCT07281664 | NOT_YET_RECRUITING | NA

30 participants

Transarterial Chemoembolization With Low-Dose Bevacizumab Plus Atezolizumab as First-Line Treatment for Unresectable Hepatocellular Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2026-01-01
Completion:: 2028-12-31

Conditions

Hepatocellular Carcinoma
Transarterial Chemoembolization

Interventions

PROCEDURE
DRUG

No Results Yet

NCT07281651 | RECRUITING

135 participants

Investigating the Role of Central Pain Hypersensitivity in Skeletal Muscle Neural Drive

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-11-24
Completion:: 2026-09-30

Conditions

Chronic Knee Pain
Fibromyalgia

Interventions

OTHER

No Results Yet

NCT07281625 | RECRUITING | EARLY_PHASE1

60 participants

Decompressive Laminectomy Versus Laminectomy With Transpedicular Fixation in Lumbar Spinal Stenosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-10-01
Completion:: 2025-12-31

Conditions

Lumbar Spinal Stenosis

Interventions

PROCEDURE

No Results Yet

NCT07281612 | COMPLETED | EARLY_PHASE1

190 participants

Hand-made Extracorporeal Knotting Versus Clip for Stump Closure in Laparoscopic Appendectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-03-01
Completion:: 2025-11-30

Conditions

Appendicectomy

Interventions

PROCEDURE

No Results Yet

NCT07281586 | RECRUITING | PHASE4

44 participants

Step-down Therapy After Long-term Osteoporosis Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2026-01-01
Completion:: 2028-12-31

Conditions

Osteoporosis

Interventions

DRUG

No Results Yet

NCT07281560 | NOT_YET_RECRUITING

300 participants

Opinions, Perceptions, & Thoughts of British Resident Doctors on Orthopaedics

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-15
Start Date:: 2026-01-15
Completion:: 2026-04-14

Conditions

Perceptions of Orthopaedic Surgery Among UK Resident Doctors

No Results Yet

NCT07281534 | RECRUITING | NA

30 participants

Test-Retest Reliability of Cardiopulmonary Exercise Testing With Echocardiography

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-11-01
Completion:: 2026-03-01

Conditions

Dyspnea; Cardiac

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07281508 | RECRUITING | PHASE3

100 participants

Transtympanic STS Against Cisplatin-induced SNHL: the SOUND Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-08-14
Completion:: 2030-03-23

Conditions

Cisplatin-related Hearing Loss

Interventions

DRUG

No Results Yet

NCT07281469 | NOT_YET_RECRUITING | NA

60 participants

Comparison of Functional Outcomes of Closed Reduction With Cast Versus Closed Reduction With K-Wire Fixation in Colles' Fracture

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-12-02
Completion:: 2026-01-18

Conditions

Colles' Fracture

Interventions

PROCEDURE

No Results Yet

NCT07281443 | ACTIVE_NOT_RECRUITING | NA

18000 participants

MDA and Targeted Control Against Plasmodium Carriage in the Sahel

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2024-09-23
Completion:: 2026-12-31

Conditions

Malaria, Falciparum
Malaria, Asymptomatic Parasitaemia

Interventions

DRUG
BEHAVIORAL
DIAGNOSTIC_TEST

No Results Yet

NCT07281339 | RECRUITING | NA

68 participants

Effect of Hypnobreastfeeding Education in High-Risk Pregnant Women

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-10-15
Completion:: 2026-05-30

Conditions

High-risk Pregnancy
Breast Feeding

Interventions

BEHAVIORAL

No Results Yet

NCT07281326 | RECRUITING | PHASE1

200 participants

A Study of AK138D1 in Advanced Malignant Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-10-22
Completion:: 2026-10-22

Conditions

Solid Cancer

Interventions

DRUG

No Results Yet

NCT07281248 | RECRUITING | NA

30 participants

TRIMODAL PREHABILITATION IN GASTROINTESTINAL CANCER

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-08-28
Completion:: 2026-09-01

Conditions

Digestive Neoplasms

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT07281235 | COMPLETED | NA

60 participants

Perioperative Analgesia Using Ultrasound Guided Erector Spinae Block vs Ultrasound Guided Caudal Block for Pain Control in Children Aged 2-7 Years Undergoing Lower Abdominal Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2024-05-01
Completion:: 2024-08-15

Conditions

Local Analgesia Via Infiltration
Caudal Epidural Anesthesia
Caudal Block
Caudal Block for Postoperative Analgesia
Caudal Anesthesia
Erector Spinae Plane Block
Children

Interventions

PROCEDURE

No Results Yet

NCT07281209 | NOT_YET_RECRUITING | PHASE2

40 participants

A Study of SHR-A1811 Combined With Adebelimumab as Neoadjuvant Therapy for Resectable HER2-Altered Non-Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-12-31
Completion:: 2027-12-31

Conditions

NSCLC

Interventions

DRUG

No Results Yet

NCT07281183 | COMPLETED | NA

40 participants

Reformer Pilates and Manual Therapy in Women With Chronic Low Back Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-03-28
Completion:: 2025-07-19

Conditions

Low Back Pain
Pilates Exercise

Interventions

OTHER

No Results Yet

NCT07281105 | COMPLETED | PHASE2

131 participants

EG-501 for Cognitive Impairment in Neuropsychiatric SLE (NPSLE): Efficacy and Safety Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2018-08-23
Completion:: 2025-08-12

Conditions

Neuropsychiatric Systemic Lupus Erythematosus
Systemic Lupus Erythematosus (SLE)
Cognitive Impairment

Interventions

DRUG

No Results Yet

NCT07281092 | RECRUITING | NA

36 participants

Comparative Efficacy of Organizational Skills Training (OST) and Mindfulness-Based Intervention (MBI)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-10-01
Completion:: 2026-06-01

Conditions

ADHD
ADHD - Attention Deficit Disorder With Hyperactivity

Interventions

BEHAVIORAL

No Results Yet

NCT07281066 | COMPLETED

120 participants

LLM Performance in Endodontic Diagnostics

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-07-07
Completion:: 2025-08-05

Conditions

Endodontic Diagnosis, Endodontic Diseases, Endodontic Treatment, Endodontic Decision-making

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07281053 | COMPLETED | NA

55 participants

E-PRF vs Collagen Membranes in Ridge Preservation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-02-20
Completion:: 2025-11-01

Conditions

Ridge Preservation

Interventions

PROCEDURE

No Results Yet

NCT07281040 | RECRUITING

10 participants

Preparatory Work for a Trial of Adjuncts to Diuretic Treatment in Patients Hospitalised With Heart Failure: Addressing Uncertainties and Building Consensus

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-07-02
Completion:: 2026-10-01

Conditions

Heart Failure

Interventions

OTHER

No Results Yet

NCT07281001 | RECRUITING | NA

60 participants

A Study to Assess the Efficiency of Trastuzumab Deruxtecan in Russian Breast Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-12-31
Completion:: 2026-05-31

Conditions

HER2-positive Breast Cancer
Trastuzumab Deruxtecan

Interventions

DRUG

No Results Yet

NCT07280988 | ACTIVE_NOT_RECRUITING | NA

22 participants

Effectiveness of Slip Resistant Footwear in Dairy Industry

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-09-01
Completion:: 2025-12-10

Conditions

Slips
Falls Prevention
Perceived Slipperiness

Interventions

DEVICE

No Results Yet

NCT07280975 | NOT_YET_RECRUITING | NA

156 participants

Comparing Polyglactin vs Polypropylene Sutures for Rectus Sheath Closure

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2026-04-01
Completion:: 2027-06-30

Conditions

Chronic Pain
Wound Dehiscence
Surgical Site Infection (SSI)
Incisional Hernia
Rectus Sheath Closure
Abdominal Surgery

Interventions

PROCEDURE

No Results Yet

NCT07280962 | COMPLETED | NA

44 participants

Packing Versus no Packing in Perianal Abscess

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-05-01
Completion:: 2025-10-30

Conditions

Perianal Abccess

Interventions

PROCEDURE

No Results Yet

NCT07280949 | RECRUITING | NA

50 participants

Posterior Transversus Abdominis Plane Block Combined With Sacral Multifidus Plane Block Versus Posterior Transversus Abdominis Plane Block for Laparoscopic Colorectal Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2026-01-31
Completion:: 2026-06-30

Conditions

Anesthesia
Posterior Transversus Abdominis Plane Block
Sacral Multifidus Plane Block
Laparoscopic Colorectal Surgery

Interventions

PROCEDURE

No Results Yet

NCT07272980 | COMPLETED | NA

48 participants

Three-Session Non-Surgical Periodontal Therapy Improves Biochemical and Microbiological Profiles in Patients With Severe Grade C Periodontitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2010-11-21
Completion:: 2011-05-22

Conditions

Periodontitis (Stage 3)
Periodontitis Stage III

Interventions

PROCEDURE

No Results Yet

NCT07272109 | NOT_YET_RECRUITING | PHASE3

210 participants

Active Anti-diabetic Treatment Plus Chemotherapy for Pancreatic Cancer Related Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2026-01-01
Completion:: 2027-12-30

Conditions

Pancreatic Cancer

Interventions

DRUG
OTHER

No Results Yet

NCT07271771 | RECRUITING | PHASE4

40 participants

The Effect of Denosumab on Muscle and Strength and Insulin Sensitivity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2024-05-21
Completion:: 2027-03-01

Conditions

Osteoporosis

Interventions

DRUG

No Results Yet

NCT07269743 | RECRUITING

423 participants

AEROSOL THERAPY IN ARDS PATIENTS (AERO-IN-ARDS)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-12-10
Completion:: 2026-12-01

Conditions

ARDS (Acute Respiratory Distress Syndrome) Receiving IMV

Interventions

DRUG

No Results Yet

NCT07269600 | ACTIVE_NOT_RECRUITING

31 participants

Effects of Sarcopenia on Proprioception, Kinesiophobia, and Pressure Pain Threshold

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-04-01
Completion:: 2025-12-31

Conditions

Sarcopenia in Elderly

No Results Yet

NCT07268547 | ENROLLING_BY_INVITATION | PHASE4

105 participants

Wrist Reduction Intervention: Supracondylar Technique for Radial Nerve Block vs. Hematoma Block (WRIST Block Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-12-09
Completion:: 2027-12-01

Conditions

Wrist Fracture

Interventions

PROCEDURE

No Results Yet

NCT07267832 | COMPLETED | NA

83 participants

Impact of Health Promotion Service-Learning for Older Adults in Physiotherapy Students

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2022-03-03
Completion:: 2022-04-17

Conditions

Healthy Students

Interventions

OTHER

No Results Yet

NCT07267520 | COMPLETED | NA

108 participants

The Effects of Quartz Crystal Singing Bowl Music and Guided Relaxation on Mood and Sleep in Rangatahi (Young Adults)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2024-03-22
Completion:: 2024-10-11

Conditions

Healthy Young Adults

Interventions

BEHAVIORAL

No Results Yet