Clinical Trials Updated in 2025

NCT06230471 | RECRUITING | PHASE2

60 participants

Pembrolizumab With or Without Lenvatinib or Chemotherapy in First-Line Treatment of Advanced Biliary Tract Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-01-09
Completion:: 2025-12-31

Conditions

Biliary Tract Neoplasms Immunotherapy

Interventions

DRUG

No Results Yet

NCT06185829 | RECRUITING | NA

64 participants

Evaluating the Benefit of Hypnoanalgesia Versus Neuroleptanalgesia During Hand Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-10-19
Completion:: 2026-11-30

Conditions

Hand Surgery

Interventions

DRUG
OTHER

No Results Yet

NCT06128395 | COMPLETED

1207 participants

ASA 81 mg vs 162 mg During Frozen Embryo Transfer (FET)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-11-01
Completion:: 2024-08-30

Conditions

Fertility Disorders

Interventions

OTHER

No Results Yet

NCT06105918 | ACTIVE_NOT_RECRUITING | PHASE1

6 participants

Radioligand Therapy After PSMA PET Guided External Beam Radiotherapy for Treating Post-Prostatectomy Patients With Biochemically Recurrent Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-11-29
Completion:: 2028-04-01

Conditions

Biochemically Recurrent Prostate Carcinoma
Prostate Adenocarcinoma

Interventions

PROCEDURE
RADIATION
OTHER
DRUG

No Results Yet

NCT06081829 | ACTIVE_NOT_RECRUITING | PHASE2

12 participants

A Phase 2 Study of Ivosidenib in Previously Treated Japanese Subjects With Nonresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-10-10
Completion:: 2024-10-01

Conditions

Cholangiocarcinoma Non-resectable
Cholangiocarcinoma Metastatic

Interventions

DRUG

Results Available

NCT06053827 | COMPLETED

1207 participants

Natural Frozen Embryo Transfer (FET) vs Substituted Frozen Embryo Transfer (FET)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-09-19
Completion:: 2023-11-30

Conditions

Fertility Disorders

Interventions

OTHER

No Results Yet

NCT06018441 | COMPLETED

112 participants

A Study to Evaluate the Quality of Life in Male and Female Adult Participants With Severe Asthma Treated With Dupilumab in a Real-world Setting

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-10-03
Completion:: 2025-10-10

Conditions

Asthma

No Results Yet

NCT06004167 | COMPLETED | NA

10 participants

Adaptive Bridging RT in R/R B-cell Lymphoma (Pre-CAR T)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2024-01-14
Completion:: 2024-10-01

Conditions

Lymphoma, B-Cell
Relapsed Cancer
Refractory Lymphoma
Diffuse Large B Cell Lymphoma
Mediastinal Large B-cell Lymphoma
High-grade B-cell Lymphoma
Follicular Lymphoma
Mantle Cell Lymphoma

Interventions

RADIATION

No Results Yet

NCT06002581 | RECRUITING | NA

56 participants

Repetitive Transcranial Magnetic Stimulation(rTMS) Regulating Slow-wave to Delay the Progression of Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-09-03
Completion:: 2026-07-28

Conditions

Parkinson's Disease

Interventions

DEVICE

No Results Yet

NCT05996016 | RECRUITING

400 participants

Gut and Vaginal Microbiota Profile Study for HIV Women

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2017-01-01
Completion:: 2029-01-01

Conditions

HPV
HIV Infections
Vaginal Microbiota

Interventions

OTHER

No Results Yet

NCT05981521 | COMPLETED

7141 participants

Paternal Age and Fetal Aneuploidy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-07-31
Completion:: 2024-12-31

Conditions

Trisomy 21

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05961098 | COMPLETED | PHASE2

48 participants

A Study of RBD1016 in CHB Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-10-11
Completion:: 2025-04-29

Conditions

Chronic Hepatitis b

Interventions

DRUG

No Results Yet

NCT05920382 | RECRUITING | NA

86 participants

Radiofrequency Ablation for the Treatment of Post-knee Arthroplasty Chronic Pain.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-09-25
Completion:: 2026-09-01

Conditions

Chronic Post-surgical Pain
Chronic Post Operative Pain
Chronic Knee Pain

Interventions

PROCEDURE

No Results Yet

NCT05914506 | ACTIVE_NOT_RECRUITING

30 participants

Hyperpolarized 129-Xenon MRI in Fibrosing Interstitial Lung Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-10-05
Completion:: 2028-05-01

Conditions

Progressive Fibrosing Interstitial Lung Disease

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05913726 | COMPLETED

55 participants

MDT Conferences for People With Diabetes and Multimorbidity

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-08-01
Completion:: 2025-06-30

Conditions

Diabetes Mellitus
Comorbidities and Coexisting Conditions

No Results Yet

NCT05912816 | RECRUITING | PHASE2

20 participants

Combination of DV and Tislelizumab for Renal Preservation in High-risk UTUC Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-06-10
Completion:: 2025-11-03

Conditions

Upper Urinary Tract Urothelial Carcinoma
Kidney Preservation
HER-2 ADC
PD-1antibody

Interventions

DRUG

No Results Yet

NCT05900401 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

20 participants

Delayed Tolerance Through Mixed Chimerism

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-10-01
Completion:: 2028-12-31

Conditions

Kidney Failure
Kidney Transplant; Complications
Chimera

Interventions

OTHER
PROCEDURE
DRUG

No Results Yet

NCT05888597 | COMPLETED | PHASE2

20 participants

Efficacy of L-menthol on Breathlessness in Chronic Obstructive Pulmonary Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-05-24
Completion:: 2025-04-30

Conditions

Chronic Obstructive Pulmonary Disease (COPD)

Interventions

DRUG
OTHER

No Results Yet

NCT05873725 | COMPLETED

118 participants

Retrospective Study of High Dose Follitropin Delta in a Mixed Protocol With Human Chorionic Gonadotropin

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-05-20
Completion:: 2023-09-30

Conditions

IVF
Infertility

Interventions

DRUG

No Results Yet

NCT05776667 | ACTIVE_NOT_RECRUITING | NA

16 participants

Feasibility Trial of Preoperative 5-Day Hypofractionated Radiotherapy for Primary Soft Tissue Sarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-08-15
Completion:: 2025-11-18

Conditions

Soft Tissue Sarcoma

Interventions

RADIATION

No Results Yet

NCT05757973 | APPROVED_FOR_MARKETING

Pre-Approval Access Program for Talquetamab in Relapsed or Refractory Multiple Myeloma

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-12-09

Conditions

Relapsed or Refractory Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05740475 | COMPLETED | PHASE1

32 participants

A Study to Evaluate the Safety, Tolerability and Pharmacokinetic Properties of 9MW3811 in Healthy Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-03-20
Completion:: 2023-09-14

Conditions

Pulmonary Fibrosis
Tumor

Interventions

DRUG

No Results Yet

NCT05730257 | ACTIVE_NOT_RECRUITING | NA

106 participants

Study Investigating Whether Robot-assisted Surgery Can Reduce Surgical Complications Following Kidney Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-05-08
Completion:: 2025-10-26

Conditions

End Stage Renal Disease
Kidney Transplant; Complications

Interventions

PROCEDURE

No Results Yet

NCT05726786 | RECRUITING | PHASE3

232 participants

The Role of Preoperative Immunonutrition on Morbidity and Immune Response After Cystectomy (INCyst Trial)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-04-10
Completion:: 2026-08-31

Conditions

Bladder Cancer
Interstitial Cystitis
Painful Bladder Syndrome
Neurogenic Bladder
Hemorrhagic Cystitis
Endometriosis
Bladder Disease

Interventions

DRUG

No Results Yet

NCT05722184 | COMPLETED

1724 participants

Diagnostic Evaluation Study of the BactInsight Blood Culture System in West-Africa

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-06-08
Completion:: 2025-05-08

Conditions

Bacterial Infections

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05721937 | RECRUITING

400 participants

A Study of How Safe Abrocitinib (CIBINQO) is in Pregnant Women and Their Offspring

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-07-25
Completion:: 2027-12-31

Conditions

Atopic Dermatitis

Interventions

DRUG

No Results Yet

NCT05713890 | RECRUITING | NA

60 participants

Home-based Action Observation Treatment With Virtual-reality for Arm Rehabilitation in People With Multiple Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-11-02
Completion:: 2026-09-30

Conditions

Multiple Sclerosis

Interventions

OTHER

No Results Yet

NCT05663216 | RECRUITING

180 participants

Determinants of Vascular Leakage During Systemic Inflammatory Response Syndrome

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-05-31
Completion:: 2028-07-01

Conditions

Systemic Inflammatory Response Syndrome

Interventions

OTHER

No Results Yet

NCT05661019 | COMPLETED

56 participants

Clinical Feasibility of the Myotrace Measurement

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2024-05-15
Completion:: 2025-01-09

Conditions

Respiratory Disease

Interventions

OTHER

No Results Yet

NCT05650021 | COMPLETED | NA

17 participants

Rectal Spacer for Prostate Cancer Radiation Image Guidance

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2024-03-08
Completion:: 2025-09-15

Conditions

Prostate Cancer

Interventions

DEVICE

No Results Yet

NCT05646394 | RECRUITING

150 participants

Registry on Augmented Antithrombotic Treatment Regimens for Patients With Arterial Thrombotic APS

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-07-01
Completion:: 2029-07-31

Conditions

Antiphospholipid Syndrome
Arterial Thrombosis

Interventions

DRUG

No Results Yet

NCT05642481 | COMPLETED

16 participants

Therapeutic Drug Monitoring to oPtimize ANtiretroviral regimeNs in HIV-infected Women Who wAnt to Breastfeed

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-03-01
Completion:: 2025-12-01

Conditions

HIV-1-infection

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05642260 | RECRUITING | NA

90 participants

Effects of Fall Prevention Program on the Number of Falls Among Elderly Following Total Knee Replacement

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-01-08
Completion:: 2026-04-30

Conditions

Fall
Osteo Arthritis Knee
Total Knee Replacement

Interventions

OTHER

No Results Yet

NCT05633875 | RECRUITING

80 participants

Multimodal Imaging Signatures of the Biological Mechanisms Underlying Neurodegeneration in Multiple Sclerosis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-04-25
Completion:: 2026-06-25

Conditions

Multiple Sclerosis (MS)

Interventions

OTHER

No Results Yet

NCT05619653 | ACTIVE_NOT_RECRUITING | PHASE3

279 participants

Myocardial Protection in Patients With Post-acute Inflammatory Cardiac Involvement Due to COVID-19

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-12-12
Completion:: 2025-08-08

Conditions

COVID-19 Associated Cardiac Involvement
Remodeling, Left Ventricle
Remodeling, Vascular
Left Ventricular Dysfunction
Exercise Intolerance
Vascular Inflammation
Microvascular Angina
Long COVID
Myocarditis, Pericarditis

Interventions

DRUG

No Results Yet

NCT05595408 | RECRUITING

84 participants

Circulating and Urine Tumor DNA Dynamics Predict Minimal Residual Disease and Recurrence Risk in Locally Advanced Upper Tract Urothelial Carcinoma

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-02-01
Completion:: 2025-11-03

Conditions

Muscle Invasive Upper Tract Urothelial Carcinoma

Interventions

DRUG

No Results Yet

NCT05585749 | COMPLETED | NA

78 participants

Virtual Reality Application on Pain Intensity and Anxiety Level in Endoscopy Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-09-05
Completion:: 2023-01-30

Conditions

Anxiety

Interventions

OTHER

No Results Yet

NCT05579717 | COMPLETED | NA

40 participants

Examining the Effectiveness of EAL

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-03-01
Completion:: 2025-08-31

Conditions

Trauma

Interventions

BEHAVIORAL

No Results Yet

NCT05567172 | COMPLETED | NA

43 participants

Watchman FLX Pro CT Pilot Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-03-24
Completion:: 2024-10-14

Conditions

Non-valvular Atrial Fibrillation (AF)

Interventions

DEVICE

Results Available

NCT05561400 | COMPLETED | NA

10 participants

Combining tDCS and CILT in Non-fluent Aphasia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-04-24
Completion:: 2023-12-15

Conditions

Aphasia
Non-fluent Aphasia
Stroke
Brain Injuries

Interventions

DEVICE
OTHER

Results Available