Clinical Trials

NCT03735121 | COMPLETED | PHASE3

438 participants

A Study to Investigate Atezolizumab Subcutaneous in Patients With Previously Treated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2018-12-27

Completion:

2022-04-26

Conditions

• Non-Small Cell Lung Cancer

Interventions

• DRUG

Results Available

NCT03725605 | COMPLETED | PHASE2

6 participants

LTX-315 and Adoptive T-cell Therapy in Advanced Soft Tissue Sarcoma (ATLAS-IT-04)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2018-12-28

Completion:

2021-07-02

Conditions

• Soft Tissue Sarcoma

Interventions

• COMBINATION_PRODUCT

Results Available

NCT03678831 | COMPLETED

45 participants

Characteristics of Marrow Fatty Cells in the Ageing of Bone and Joints, Osteoarthritis and Osteoporosis

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-05

Start Date:

2020-06-30

Completion:

2024-03-11

Conditions

• Osteoarthritis, Knee
• Prosthesis User

Interventions

• PROCEDURE

No Results Yet

NCT03668223 | COMPLETED | NA

195 participants

The PRISM Intervention: a Multi-site Randomized Controlled Trial for Adolescents and Young Adults With Advanced Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2019-04-15

Completion:

2024-01-23

Conditions

• Cancer
• Quality of Life
• Anxiety
• Depression
• Hope
• Coping Skills
• Communication

Interventions

• BEHAVIORAL

Results Available

NCT03620903 | ACTIVE_NOT_RECRUITING | PHASE2

53 participants

Efficacy of First Line B-RI for Treatment Naive Waldenström's Macroglobulinemia

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2019-09-11

Completion:

2022-11-14

Conditions

• Waldenstrom Macroglobulinemia

Interventions

• DRUG

No Results Yet

NCT03612609 | COMPLETED | NA

10 participants

Pilot Study to Detect DENGUE Virus in Sperm

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2019-02-06

Completion:

2019-08-07

Conditions

• Dengue

Interventions

• BIOLOGICAL

No Results Yet

NCT03526679 | COMPLETED | PHASE1/PHASE2

30 participants

Lenvatinib and Eribulin in Advanced Soft Tissue Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2018-07-12

Completion:

2021-06-30

Conditions

• Leiomyosarcoma
• Liposarcoma
• Soft Tissue Sarcoma Adult
• Advanced Cancer

Interventions

• DRUG

Results Available

NCT03482986 | ACTIVE_NOT_RECRUITING | NA

44 participants

Role of Dietary Habits in Efficacy of Bariatric Surgery - Study C

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2021-12-07

Completion:

2028-06-30

Conditions

• Bariatric Surgery
• Sleeve Gastrectomy
• Obesity

Interventions

• BEHAVIORAL

No Results Yet

NCT03477292 | COMPLETED | NA

41 participants

7-days Versus 14 Days of Antibiotics Therapy for Ventilator Associated Pneumonia

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2018-03-01

Completion:

2024-10-31

Conditions

• Ventilator Associated Pneumonia

Interventions

• DRUG

No Results Yet

NCT03462849 | COMPLETED | NA

25 participants

Expiratory Flow Limitation Assessment

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2018-02-05

Completion:

2019-05-02

Conditions

• Acute Respiratory Distress Syndrome

Interventions

• OTHER

No Results Yet

NCT03420118 | RECRUITING | NA

1000 participants

Study of Biomarkers in Gynecological Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2017-12-21

Completion:

2026-12-21

Conditions

• Gynecologic Cancer

Interventions

• PROCEDURE

No Results Yet

NCT03418220 | COMPLETED | NA

82 participants

Comparison of Cytokine Profiles in Aqueous Humor of Patients With Age Related Macular Degeneration (AMD)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2017-11-22

Completion:

2020-09-08

Conditions

• Macular Degeneration, Age-Related

Interventions

• OTHER

No Results Yet

NCT03381183 | COMPLETED | PHASE1

19 participants

IRX-2 Regimen and Durvalumab, for Incurable H&N Squamous Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2019-08-21

Completion:

2022-05-12

Conditions

• Squamous Cell Carcinoma
• Squamous Cell Carcinoma of the Head and Neck
• Metastatic Squamous Cell Carcinoma
• Oral Cavity Squamous Cell Carcinoma
• Oropharynx Squamous Cell Carcinoma
• Paranasal Sinus Squamous Cell Carcinoma
• Hypopharynx Squamous Cell Carcinoma
• Larynx Squamous Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT03380078 | ENROLLING_BY_INVITATION | NA

1206 participants

Translating Evidence-based Interventions for ASD: Multi-Level Implementation Strategy

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2017-10-20

Completion:

2027-08-31

Conditions

• Autism Spectrum Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT03340194 | COMPLETED

214 participants

Evaluation of Calcinosis in Systemic Sclerosis

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-05

Start Date:

2017-11-30

Completion:

2019-05-14

Conditions

• Systemic Sclerosis

Interventions

• RADIATION
• PROCEDURE

No Results Yet

NCT03336320 | COMPLETED | NA

120 participants

Feasibility and Acceptability of a Web-based Multidomain Intervention to Maintain Cognitive Function in Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2017-11-23

Completion:

2019-01-31

Conditions

• Aged

Interventions

• DEVICE

No Results Yet

NCT03299959 | COMPLETED | NA

251 participants

Agili-C™ Implant Performance Evaluation

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2017-09-25

Completion:

2024-11-14

Conditions

• Cartilage or Osteochondral Defects in the Knee
• Up to Moderate Osteoarthritis

Interventions

• DEVICE
• PROCEDURE

Results Available

NCT03293069 | COMPLETED | PHASE2/PHASE3

372 participants

Conservative Iron Chelation as a Disease-modifying Strategy in Amyotrophic Lateral Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2019-01-30

Completion:

2023-11-11

Conditions

• Amyotrophic Lateral Sclerosis

Interventions

• DRUG

No Results Yet

NCT03248284 | RECRUITING

30 participants

Immune-Competent Cell Manifestations in Psoriatic Arthritis Achilles Tendons

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-05

Start Date:

2017-08-21

Completion:

2026-12-31

Conditions

• Psoriatic Arthritis
• Enthesitis

Interventions

• PROCEDURE

No Results Yet

NCT03229863 | ACTIVE_NOT_RECRUITING | NA

102 participants

An Examination of Infants' Microbiome, Nutrition, and Development Study.

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2017-04-18

Completion:

2020-03-10

Conditions

• Microbial Colonization
• Infant Development

Interventions

• OTHER

No Results Yet

NCT03177291 | COMPLETED | PHASE1

48 participants

Pirfenidone Combined With Standard First-Line Chemotherapy in Advanced-Stage Lung NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2017-09-26

Completion:

2021-05-09

Conditions

• Lung Cancer
• Non Small Cell Lung Cancer
• Advanced Cancer
• Metastatic Lung Cancer
• Squamous Cell Lung Cancer
• Non-Squamous Non-Small Cell Neoplasm of Lung

Interventions

• DRUG

No Results Yet

NCT03163771 | COMPLETED

8 participants

Evaluation of a New Strategy for the Diagnosis of Peroxisomal Diseases

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-05

Start Date:

2018-12-18

Completion:

2022-08-15

Conditions

• Peroxisomal Disorders
• Diagnoses Disease

No Results Yet

NCT03123835 | ENROLLING_BY_INVITATION | NA

500 participants

Outcome Analysis of POEM and Endoluminal Therapies

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2016-03-31

Completion:

2030-12-31

Conditions

• Achalasia
• Gastric Fistula
• Weight Gain After Primary Weight Loss Surgery
• Marginal Ulcer
• Stenoses
• Gastric Nec

Interventions

• PROCEDURE

No Results Yet

NCT03118050 | COMPLETED | NA

95 participants

Identifying Therapeutic Targets of Accelerated Sarcopenia

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2017-05-28

Completion:

2023-08-21

Conditions

• Sarcopenia
• Diabetes Mellitus
• Aging

Interventions

• BEHAVIORAL

Results Available

NCT03107884 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

64 participants

Role of Metformin on Muscle Health of Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2019-08-01

Completion:

2026-11-01

Conditions

• Muscle Atrophy
• Insulin Resistance

Interventions

• DRUG

No Results Yet

NCT03007732 | COMPLETED | PHASE2

23 participants

Pembrolizumab +/- SD-101 in Hormone-Naïve Oligometastatic Prostate Cancer With RT and iADT

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2017-05-17

Completion:

2025-03-31

Conditions

• Prostatic Neoplasms

Interventions

• DRUG
• RADIATION

Results Available

NCT02932280 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

14 participants

Safety and Dose Finding Study of Neratinib in Children and Young Adults With Cancer That Has Returned or Not Responded to Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2016-10-31

Completion:

2026-10-31

Conditions

• Solid Tumor
• Central Nervous System Tumor
• Lymphoma
• Leukemia

Interventions

• DRUG

No Results Yet

NCT02911805 | ACTIVE_NOT_RECRUITING | NA

14 participants

Bridging Animal and Human Models of Exercise-induced Visual Rehabilitation

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2015-06-10

Completion:

2022-06-14

Conditions

• Vision Disorders

Interventions

• BEHAVIORAL

Results Available

NCT02804373 | COMPLETED | PHASE2/PHASE3

50 participants

Effects of Intranasal Administration of Oxytocin in Adults With Prader-Willi Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2014-06-30

Completion:

2019-01-31

Conditions

• Prader-Willi Syndrome

Interventions

• DRUG

No Results Yet

NCT02754037 | ACTIVE_NOT_RECRUITING

120 participants

Non-alcoholic Fatty Liver Disease Parametric PET (FLiPP) Study

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-05

Start Date:

2016-04-30

Completion:

2026-06-30

Conditions

• Non-alcoholic Fatty Liver Disease (NAFLD)
• Non-alcoholic Steatohepatitis (NASH)

Interventions

• RADIATION
• OTHER

No Results Yet

NCT02741986 | ACTIVE_NOT_RECRUITING

200 participants

Integrating Data, Algorithms and Clinical Reasoning for Surgical Risk Assessment

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-05

Start Date:

2016-10-31

Completion:

2028-11-30

Conditions

• Postoperative Complications

Interventions

• OTHER

No Results Yet

NCT02573415 | ACTIVE_NOT_RECRUITING | NA

10 participants

Uterine Transplantation for the Treatment of Uterine Factor Infertility

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2015-10-31

Completion:

2026-12-31

Conditions

• Primary Uterine Infertility

Interventions

• PROCEDURE

No Results Yet

NCT02473042 | COMPLETED | NA

188 participants

Intraoperative Acupoint Stimulation to Prevent Post-Operative Nausea and Vomiting (PONV)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2016-03-01

Completion:

2024-11-26

Conditions

• Post-Operative Nausea and Vomiting
• Breast Cancer

Interventions

• PROCEDURE
• DRUG
• BEHAVIORAL

Results Available

NCT02457338 | ACTIVE_NOT_RECRUITING | NA

120 participants

Infant Microbiota and Probiotic Intake Study

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2014-11-01

Completion:

2016-07-15

Conditions

• Healthy

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT02457052 | COMPLETED | NA

64 participants

Impact of a Transportable Customizable and Scalable Sitting Positioning Device on Swallowing Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2014-10-31

Completion:

2017-03-31

Conditions

• Deglutition Disorders

Interventions

• DEVICE

No Results Yet

NCT02437071 | COMPLETED | PHASE2

34 participants

Assess the Efficacy of Pembrolizumab Plus Radiotherapy or Ablation in Metastatic Colorectal Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2015-04-30

Completion:

2024-09-20

Conditions

• Metastatic Colorectal Cancer

Interventions

• DRUG
• RADIATION
• PROCEDURE

Results Available

NCT02378597 | COMPLETED | NA

28 participants

Resiliency Program for Medical Interpreters

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2014-01-31

Completion:

2014-03-31

Conditions

• Psychological Stress

Interventions

• BEHAVIORAL

No Results Yet

NCT02328989 | COMPLETED | NA

324 participants

Pessary to Prevent Prematurity in Twins in Case of Short Cervix

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2014-11-30

Completion:

2018-10-31

Conditions

• Pregnancy

Interventions

• DEVICE

No Results Yet

NCT02284646 | COMPLETED | NA

56 participants

Physical Training Program in Ankylosing Spondylitis

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2014-11-25

Completion:

2018-10-24

Conditions

• Ankylosing Spondylitis

Interventions

• OTHER

No Results Yet

NCT02282917 | TERMINATED | EARLY_PHASE1

7 participants

Exploratory Evaluation of AR-42 Histone Deacetylase Inhibitor in the Treatment of Vestibular Schwannoma and Meningioma

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-05

Start Date:

2015-12-31

Completion:

2017-05-30

Conditions

• Vestibular Schwannoma
• Meningioma
• Acoustic Neuroma
• Neurofibromatosis Type 2

Interventions

• DRUG

Results Available