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Evaluation of Calcinosis in Systemic Sclerosis

NCT03340194 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 214

Last updated 2025-12-05

No results posted yet for this study

Summary

Systemic sclerosis is a rare pathology characterized by fibrosis and vascular lesion with skin, pulmonary, digestive and cardiac localisation. Calcinosis cutis is commonly described, but its prevalence and appear few documented in literature. Moreover, this studies used clinical observation to determine presence or absence of calcification, and rarely radiography, in particular for feet localisation. In the same way, skin calcification and organ injury association appear unclear. The aim of the study is firstly to determine prevalence of calcinosis cutis, with hand and feet radiography realisation in a cohort of systemic sclerosis patient. Secondly, will be determine the correlation between calcinosis and organ injury.

Conditions

Interventions

RADIATION

Radiography

Radiography of the hand and feet (face incident) the day of the inclusion

PROCEDURE

Veinous punction

Blood sample to analysis VEGF, endothelin 1, endostatin and P/GF, (ELISA method)

Sponsors & Collaborators

  • University Hospital, Lille

    lead OTHER

Principal Investigators

  • Vincent SOBANSKI, MD · University Hospital, Lille

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-11-30
Primary Completion
2019-05-14
Completion
2021-04-02

Countries

  • France

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03340194 on ClinicalTrials.gov