Clinical Trials

NCT03906227 | TERMINATED | NA

9 participants

Tailoring Maintenance Therapy to Cluster of Differentiation 5 Positive (CD5+) Regulatory B Cell Recovery in ANCA Vasculitis

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2019-06-28

Completion:

2025-02-27

Conditions

• ANCA Associated Vasculitis

Interventions

• DEVICE

Results Available

NCT03822793 | COMPLETED | PHASE2

170 participants

A Dose-response Study of Tranexamic Acid in Total Hip Arthroplasty

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2023-12-07

Completion:

2025-04-21

Conditions

• Arthropathy of Hip

Interventions

• DRUG

No Results Yet

NCT03815721 | TERMINATED | NA

12 participants

Carry-over Effects of Repetitively Applied Transcutaneous Spinal Cord Stimulation on Spasticity

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2019-01-07

Completion:

2021-05-10

Conditions

• Spinal Cord Injuries
• Spasticity, Muscle

Interventions

• DEVICE

No Results Yet

NCT03766763 | ACTIVE_NOT_RECRUITING | PHASE2

82 participants

Preemptive Therapy for High Risk Chronic Lymphoid Leukemia Stage A

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2019-05-22

Completion:

2022-01-01

Conditions

• Chronic Lymphoid Leukemia

Interventions

• DRUG

No Results Yet

NCT03739853 | COMPLETED | PHASE4

192 participants

Severe Psoriatic Arthritis - Early intervEntion to Control Disease: the SPEED Trial

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2019-05-14

Completion:

2024-10-31

Conditions

• Psoriatic Arthritis

Interventions

• DRUG

Results Available

NCT03734198 | ACTIVE_NOT_RECRUITING | PHASE2

29 participants

Evaluation of the Safety and Efficacy of the Association of Ibrutinib and Daratumumab in Relapsed/Refractory Chronic Lymphocytic Leukemia With p53 Dysfunction

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2018-12-19

Completion:

2023-06-17

Conditions

• Relapsed or Refractory Chronic Lymphocytic Leukemia

Interventions

• DRUG

No Results Yet

NCT03702309 | RECRUITING

2500 participants

Liquid Biopsy Evaluation and Repository Development at Princess Margaret

Study Type:

OBSERVATIONAL

Last Updated:

2025-11-26

Start Date:

2017-08-03

Completion:

2026-07-06

Conditions

• Cancer
• Breast Cancer
• Lung Cancer
• Colon Cancer
• Ovarian Cancer
• Melanoma
• Lymphoma
• Leukemia
• Mutation
• Lynch Syndrome
• Cowden Syndrome
• BRCA1 Mutation
• BRCA2 Mutation
• Uterine Cancer
• Myeloma
• Kidney Cancer
• Head and Neck Cancer
• Meningioma

No Results Yet

NCT03621254 | RECRUITING | NA

20 participants

Investigation Into Optimal FES Training Characteristics After Spinal Cord Injury

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2019-01-07

Completion:

2026-12-31

Conditions

• Spinal Cord Injury

Interventions

• OTHER

No Results Yet

NCT03589326 | ACTIVE_NOT_RECRUITING | PHASE3

245 participants

A Study of Ponatinib Versus Imatinib in Adults With Acute Lymphoblastic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2018-10-04

Completion:

2022-08-12

Conditions

• Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL)

Interventions

• DRUG

Results Available

NCT03572738 | COMPLETED

67 participants

Hidradenitis Suppurativa Mail Survey

Study Type:

OBSERVATIONAL

Last Updated:

2025-11-26

Start Date:

2018-05-14

Completion:

2020-06-30

Conditions

• Hidradenitis Suppurativa

No Results Yet

NCT03571633 | ACTIVE_NOT_RECRUITING | PHASE2

90 participants

Impact of Pegfilgrastim on Trastuzumab Anti-tumor Effect and ADCC in Operable HER2+ Breast Cancer Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2018-08-06

Completion:

2027-01-31

Conditions

• HER2-positive Breast Cancer
• Operable Breast Cancer

Interventions

• DRUG

No Results Yet

NCT03569449 | COMPLETED | NA

312 participants

Family Partner Navigation for Children

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2019-06-24

Completion:

2024-06-21

Conditions

• Health Behavior

Interventions

• BEHAVIORAL

Results Available

NCT03423979 | COMPLETED | PHASE2

80 participants

Optilume™ BPH Prostatic Drug Coated Balloon Dilation Catheter

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2017-12-19

Completion:

2019-06-04

Conditions

• Benign Prostatic Hyperplasia
• Benign Prostatic Hypertrophy

Interventions

• DEVICE
• DRUG

Results Available

NCT03373539 | COMPLETED

70 participants

Neurotrophin Expression in Infants as a Predictor of Respiratory and Neurodevelopmental Outcomes

Study Type:

OBSERVATIONAL

Last Updated:

2025-11-26

Start Date:

2014-12-31

Completion:

2019-08-31

Conditions

• Bronchopulmonary Dysplasia
• Chronic Lung Disease

No Results Yet

NCT03271892 | ACTIVE_NOT_RECRUITING

200 participants

Deciding on Active Surveillance or Surgery for Primary Management of Low Risk Papillary Thyroid Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2025-11-26

Start Date:

2016-05-11

Completion:

2031-12-31

Conditions

• Thyroid Cancer Stage I

No Results Yet

NCT03271762 | ACTIVE_NOT_RECRUITING | NA

330 participants

Multicentre Study of MITRACLIP® Transcatheter Mitral Valve Repair in Patients With Severe Primary Mitral Regurgitation Eligible for High-risk Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2018-03-02

Completion:

2026-12-31

Conditions

• Mitral Regurgitation

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT03270384 | COMPLETED | NA

16 participants

Re-establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2017-10-25

Completion:

2019-11-01

Conditions

• Urethral Stricture

Interventions

• DEVICE

No Results Yet

NCT03263117 | COMPLETED | PHASE4

260 participants

SEdation Versus General Anesthesia for Endovascular Therapy in Acute Ischemic Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2018-07-01

Completion:

2023-04-22

Conditions

• Stroke

Interventions

• DRUG
• PROCEDURE

Results Available

NCT03224104 | COMPLETED | PHASE1

71 participants

Multi-kinase Inhibitor TG02 (TG02) in Elderly Newly Diagnosed or Adult Relapsed Patients With Anaplastic Astrocytoma or Glioblastoma.

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2018-06-12

Completion:

2022-05-05

Conditions

• Astrocytoma, Grade III
• Glioblastoma

Interventions

• DRUG
• RADIATION

Results Available

NCT03209531 | COMPLETED | NA

11 participants

Conditioning Brain Responses to Improve Thigh Muscle Function After Anterior Cruciate Ligament Reconstruction

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2017-09-21

Completion:

2025-11-24

Conditions

• Anterior Cruciate Ligament Injury

Interventions

• BEHAVIORAL
• DEVICE

No Results Yet

NCT03201965 | COMPLETED | PHASE3

416 participants

A Study to Evaluate the Efficacy and Safety of Daratumumab in Combination With Cyclophosphamide, Bortezomib and Dexamethasone (CyBorD) Compared to CyBorD Alone in Newly Diagnosed Systemic Amyloid Light-chain (AL) Amyloidosis

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2017-10-05

Completion:

2020-02-14

Conditions

• Amyloidosis

Interventions

• DRUG

Results Available

NCT03143322 | ACTIVE_NOT_RECRUITING | NA

168 participants

Standard Treatment +/- SBRT in Solid Tumors Patients With Between 1 and 5 Bone-only Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2018-07-24

Completion:

2025-07-31

Conditions

• Metastatic Breast Cancer
• Metastatic Lung Cancer
• Metastatic Prostate Cancer
• Bone Metastases

Interventions

• RADIATION

No Results Yet

NCT03048331 | TERMINATED | NA

15 participants

Functional Electrical Stimulation (FES) and Reconstructive Tetraplegia Hand and Arm Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2017-03-01

Completion:

2025-11-19

Conditions

• Spinal Cord Injury Cervical

Interventions

• DEVICE

No Results Yet

NCT02921022 | ACTIVE_NOT_RECRUITING | NA

110 participants

Study Of Gemcitabine, Nab-paclitaxel, PEGPH20 and Rivaroxaban for Advanced Pancreatic Adenocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2016-10-31

Completion:

2026-10-31

Conditions

• Pancreatic Cancer
• Advanced Pancreatic Ductal Adenocarcinoma

Interventions

• DRUG

No Results Yet

NCT02832193 | RECRUITING

5000 participants

Retrospective Evaluation of POCD Data of Studies From KAI, Charité - Universitätsmedizin Berlin

Study Type:

OBSERVATIONAL

Last Updated:

2025-11-26

Start Date:

2009-03-31

Completion:

2027-12-31

Conditions

• Postoperative Cognitive Dysfunction

No Results Yet

NCT02811523 | RECRUITING | PHASE1

17 participants

In Vivo Lung Perfusion for Pulmonary Metastases of Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2016-02-29

Completion:

2030-09-30

Conditions

• Bone Sarcoma
• Soft Tissue Sarcoma
• Pulmonary Metastases

Interventions

• DRUG

No Results Yet

NCT02773134 | COMPLETED | NA

43 participants

The Early Impact of Postoperative Bracing on Pain and Quality of Life Following Posterior Instrumented Fusion for Lumbar Degenerative Conditions

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2009-03-31

Completion:

2016-05-31

Conditions

• Lumbar Degenerative Conditions

Interventions

• OTHER

No Results Yet

NCT02666898 | COMPLETED | PHASE2

135 participants

Phase II Trial GA101 Inbrutinib B CLL

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2015-10-31

Completion:

2017-05-31

Conditions

• Leukemia, Lymphocytic, Chronic, B-Cell

Interventions

• DRUG

No Results Yet

NCT02570542 | ACTIVE_NOT_RECRUITING | PHASE2

59 participants

Study of the Impact of CD34+ Cell Dose on Absolute Lymphocyte Count Following High-Dose Therapy and Autologous Stem Cell Transplantation for Relapsed and Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2015-10-31

Completion:

2026-10-31

Conditions

• Diffuse Large B-cell Lymphoma (DLBCL)
• Relapsed Diffuse Large B-cell Lymphoma (DLBCL)
• Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT02568553 | COMPLETED | PHASE1

35 participants

Lenalidomide and Blinatumomab for the Treatment of Relapsed Non-Hodgkin Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2016-11-15

Completion:

2025-11-24

Conditions

• Recurrent Burkitt Lymphoma
• Recurrent Diffuse Large B-Cell Lymphoma
• Recurrent Grade 1 Follicular Lymphoma
• Recurrent Grade 2 Follicular Lymphoma
• Recurrent Grade 3 Follicular Lymphoma
• Recurrent Grade 3a Follicular Lymphoma
• Recurrent Grade 3b Follicular Lymphoma
• Recurrent Gray-Zone Lymphoma
• Recurrent Mantle Cell Lymphoma
• Recurrent Marginal Zone Lymphoma
• Recurrent Mediastinal Lymphoma
• Recurrent Non-Hodgkin Lymphoma
• Recurrent Small Lymphocytic Lymphoma
• Refractory Burkitt Lymphoma
• Refractory Diffuse Large B-Cell Lymphoma
• Refractory Follicular Lymphoma
• Refractory Grade 1 Follicular Lymphoma
• Refractory Grade 2 Follicular Lymphoma
• Refractory Grade 3 Follicular Lymphoma
• Refractory Grade 3a Follicular Lymphoma
• Refractory Gray-Zone Lymphoma
• Refractory Mantle Cell Lymphoma
• Refractory Marginal Zone Lymphoma
• Refractory Mediastinal Lymphoma
• Refractory Non-Hodgkin Lymphoma
• Refractory Small Lymphocytic Lymphoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT02243397 | COMPLETED

145 participants

Molecular and Cellular Analysis of Breast Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2025-11-26

Start Date:

2014-09-10

Completion:

2021-04-19

Conditions

• Breast - Female
• Breast - Male

No Results Yet

NCT02227732 | COMPLETED | NA

10 participants

A Pilot Study Evaluating the Safety and Effectiveness of a New Pleural Catheter for the Medical Management of Symptomatic, Recurrent, Malignant Pleural Effusions

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2014-04-30

Completion:

2015-05-31

Conditions

• Malignant Pleural Effusions

Interventions

• DEVICE

No Results Yet

NCT02226146 | COMPLETED | PHASE2

11 participants

Evaluation of Safety, Efficacy and Pharmacodynamic Effect of Bertilimumab in Patients With Bullous Pemphigoid

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2016-02-29

Completion:

2018-04-30

Conditions

• Pemphigoid, Bullous

Interventions

• BIOLOGICAL

Results Available

NCT02119845 | COMPLETED | NA

16 participants

A Prospective Clinical Evaluation of the Total Vascular Access (TVA) FLEX-1 Device Protocol FLEX-1-001

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2012-08-31

Completion:

2013-04-30

Conditions

• Chronic Kidney Disease (CKD)

Interventions

• DEVICE

No Results Yet

NCT02119832 | COMPLETED | NA

17 participants

A Prospective Clinical Evaluation of the Total Vascular Access (TVA) FLEX-1 Device Protocol Flex-1-002-IR Intervention Reduction (IR)

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2013-04-30

Completion:

2014-02-28

Conditions

• Chronic Kidney Disease (CKD)

Interventions

• DEVICE

No Results Yet

NCT02036671 | COMPLETED | NA

80 participants

Novel Endovascular Access Trial (NEAT)

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2014-01-31

Completion:

2015-12-31

Conditions

• Chronic Kidney Disease

Interventions

• DEVICE

No Results Yet

NCT01992952 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

149 participants

Fulvestrant +/- Akt Inhibition in Advanced Aromatase Inhibitor Resistant Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2014-05-07

Completion:

2019-03-31

Conditions

• Estrogen Receptor Positive Breast Cancer

Interventions

• DRUG

No Results Yet

NCT01927744 | COMPLETED | PHASE2

55 participants

Study of Chemotherapy With Cisplatin/Carboplatin, and Docetaxel With or Without Erlotinib in Patients With Head and Neck Squamous Cell Carcinomas Amenable for Surgical Resection

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2013-12-16

Completion:

2025-01-06

Conditions

• Head and Neck Cancer

Interventions

• DRUG
• OTHER
• BEHAVIORAL

Results Available

NCT01898117 | ACTIVE_NOT_RECRUITING | PHASE2

304 participants

Triple-B Study;Carboplatin-cyclophosphamide Versus Paclitaxel With or Without Atezolizumab as First-line Treatment in Advanced Triple Negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-11-26

Start Date:

2013-07-31

Completion:

2024-04-01

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT01656447 | RECRUITING

300 participants

Scleroderma Registry & Repository at the Hospital for Special Surgery

Study Type:

OBSERVATIONAL

Last Updated:

2025-11-26

Start Date:

2006-08-31

Completion:

2030-01-31

Conditions

• Scleroderma

No Results Yet