Clinical Trials Updated in 2025

NCT07154511 | RECRUITING | PHASE1/PHASE2

45 participants

Phase 2 Trial of Tributyrin in People With Parkinson's Disease and Cognitive Impairments

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2025-11-07
Completion:: 2027-05-31

Conditions

Parkinson Disease
Parkinson Disease Dementia

Interventions

DRUG

No Results Yet

NCT07144631 | RECRUITING | NA

15 participants

Peroneal Electrical Nerve Stimulation in Pregnancy for Restless Legs Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2025-10-15
Completion:: 2026-09-30

Conditions

Restless Leg Disorder
Restless Leg Syndrome (RLS)
Pregnancy
Sleep Disorder (Disorder)

Interventions

DEVICE

No Results Yet

NCT07111182 | RECRUITING | NA

8 participants

Intraoperative Fluorescence-Guided Aspirate Tissue Monitoring of 5-ALA During Brain Tumor Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2025-10-27
Completion:: 2027-11-30

Conditions

Brain Neoplasms

Interventions

DEVICE

No Results Yet

NCT07101289 | RECRUITING | NA

900 participants

Eat Well Heart Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2025-10-22
Completion:: 2026-12-31

Conditions

Congestive Heart Failure Chronic

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT07095556 | RECRUITING | NA

39 participants

Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2025-11-05
Completion:: 2026-12-31

Conditions

Wound Healing and Prevention
Oral Inflammation
Photobiomodulation
Post-operative Pain Management
Tooth Extraction Site Healing

Interventions

OTHER

No Results Yet

NCT07091695 | COMPLETED

100 participants

Real-world Outcomes Among Patients With Melanoma Treated With Neoadjuvant Nivolumab+Relatlimab or Nivolumab+Ipilimumab

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-12
Start Date:: 2025-05-11
Completion:: 2025-11-06

Conditions

Melanoma

Interventions

BIOLOGICAL

No Results Yet

NCT07084168 | RECRUITING | NA

30 participants

Multimedia Aid for Genetic Testing in Gynecologic Oncology

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2024-10-10
Completion:: 2026-10-30

Conditions

Ovary Cancer
Endometrial Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT07054008 | RECRUITING | NA

25 participants

Microsurgery and Periodontal Healing

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2025-08-31
Completion:: 2027-05-31

Conditions

Periodontal Diseases

Interventions

PROCEDURE

No Results Yet

NCT07053969 | RECRUITING | NA

32 participants

The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2025-08-31
Completion:: 2027-09-30

Conditions

Dental Implantation
Missing Teeth
Periodontitis, Adult
Mucositis

Interventions

DEVICE

No Results Yet

NCT07050160 | ENROLLING_BY_INVITATION

10 participants

Long-term Follow-up Study of Gene Therapy for Arrhythmogenic Cardiomyopathy Due to a Plakophilin-2 Pathogenic Variant

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-12
Start Date:: 2025-08-29
Completion:: 2030-08-31

Conditions

Arrhythmogenic Cardiomyopathy
PKP2-ACM
PKP2-ARVC

No Results Yet

NCT07043452 | WITHDRAWN | EARLY_PHASE1

0 participants

Measuring Acute Drug Demand in Humans II

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2025-11-15
Completion:: 2027-12-01

Conditions

Healthy Volunteers

Interventions

DRUG

No Results Yet

NCT07026942 | NOT_YET_RECRUITING | PHASE1/PHASE2

42 participants

Phase I/II Clinical Trial of Universal Donor CD33 CAR Natural Killer Cells for AML

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2026-04-01
Completion:: 2032-07-01

Conditions

Relapsed/Refractory AML

Interventions

BIOLOGICAL

No Results Yet

NCT06911931 | RECRUITING | NA

84 participants

Visual Perception in Schizophrenia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2025-11-03
Completion:: 2027-01-31

Conditions

Schizophrenia Disorders
Bipolar Disorder
Schizo Affective Disorder

Interventions

OTHER

No Results Yet

NCT06804603 | COMPLETED | PHASE2

124 participants

A Study to Measure the Effects of Using Tradipitant on Nausea and Vomiting After GLP-1R Agonist Use

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2025-02-25
Completion:: 2025-10-06

Conditions

Obesity

Interventions

DRUG

No Results Yet

NCT06751602 | ENROLLING_BY_INVITATION | PHASE2

40 participants

Belumosudil for Abrogation of Interstitial Fibrosis and Tubular Atrophy Following Kidney Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2025-09-11
Completion:: 2027-12-31

Conditions

Rejection Chronic Renal

Interventions

DRUG

No Results Yet

NCT06729398 | COMPLETED | NA

129 participants

The Role of Cerebral NIRS in Preventing Brain Injury of Very Low Birth Weight Preterm Infants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2017-05-01
Completion:: 2020-05-01

Conditions

Neonatal Cerebral Leukomalacia
Intracranial Nontraumatic Haemorrhage of Fetus and Newborn
Neonatal Mortality

Interventions

DEVICE
OTHER

No Results Yet

NCT06670638 | RECRUITING

50 participants

Development of a Novel Endoscopic Index and Patient-reported Outcome Measure for Clinical Trials in Participants With Permanent Ileostomy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-12
Start Date:: 2024-06-19
Completion:: 2026-06-30

Conditions

Crohns Disease

No Results Yet

NCT06654843 | RECRUITING | NA

630 participants

Free Time For Wellness 2+

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2024-11-15
Completion:: 2026-09-30

Conditions

Physical Inactivity

Interventions

BEHAVIORAL

No Results Yet

NCT06645145 | COMPLETED | NA

170 participants

Language Learning and Language Experience

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2024-10-31
Completion:: 2025-08-30

Conditions

Typically Developing Children Ages 3 to 6

Interventions

BEHAVIORAL

No Results Yet

NCT06619756 | COMPLETED | NA

2 participants

Anomia Treatment Predictors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2024-09-18
Completion:: 2025-10-01

Conditions

Aphasia
Anomia (Word-Finding Impairment)

Interventions

BEHAVIORAL

No Results Yet

NCT06610617 | COMPLETED | NA

48 participants

Neuromodulation of Central Sensory Integration to Improve Postural Control

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2024-10-14
Completion:: 2025-06-17

Conditions

Survivorship
Quality of Life
Cognitive Deficits, Mild

Interventions

DEVICE

No Results Yet

NCT06601296 | RECRUITING | PHASE2

15 participants

Radiotherapy in Combination With Checkpoint Inhibition for Patients With Metastatic Kidney Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2025-04-01
Completion:: 2027-10-31

Conditions

Metastatic Renal Cell Carcinoma ( mRCC)
OligoProgressive Metastatic Disease

Interventions

DRUG

No Results Yet

NCT06600906 | RECRUITING

70 participants

Hyperpolarized 13C MRI to Predict Response in Pancreatic Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-12
Start Date:: 2024-10-01
Completion:: 2030-08-01

Conditions

Pancreatic Ductal Adenocarcinoma
Metastatic Pancreatic Ductal Adenocarcinoma
Locally Advanced Pancreatic Ductal Adenocarcinoma

Interventions

DRUG
PROCEDURE

No Results Yet

NCT06575660 | COMPLETED | NA

22 participants

Digital Support for Mental Health Intervention in Patients With Inflammatory Bowel Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2024-09-23
Completion:: 2025-10-09

Conditions

Depression
Inflammatory Bowel Diseases
Anxiety
Ulcerative Colitis
Crohn Disease

Interventions

BEHAVIORAL

No Results Yet

NCT06565416 | RECRUITING | NA

225 participants

Opioid and Pain Treatment in Indigenous Communities (OPTIC) Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2023-06-01
Completion:: 2026-07-31

Conditions

Opioid Use Disorder
Opioid Misuse
Chronic Pain

Interventions

BEHAVIORAL

No Results Yet

NCT06539754 | COMPLETED | NA

61 participants

Patient Satisfaction During Cesarean Delivery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2024-11-25
Completion:: 2025-11-10

Conditions

Patient Satisfaction

Interventions

BEHAVIORAL

No Results Yet

NCT06536374 | NOT_YET_RECRUITING | PHASE2

50 participants

Folate Study in Men With Advanced Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2026-06-30
Completion:: 2027-12-31

Conditions

Prostate Cancer

Interventions

DRUG

No Results Yet

NCT06521567 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

83 participants

A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2025-03-06
Completion:: 2026-10-13

Conditions

Melanoma
Hodgkin Lymphoma
High and Low Grade Glioma
Glioblastoma Multiforme (GBM)
Diffuse Intrinsic Pontine Glioma (DIPG)
Ependymoma
Osteosarcoma
Hepatic Tumors
Hepatoblastoma
Hepatocellular Carcinoma (HCC)
Fibrolamellar Carcinoma
Rhabdomyosarcoma

Interventions

DRUG

No Results Yet

NCT06518616 | RECRUITING | PHASE2

192 participants

Meditation to Reduce Firefighter Distress

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2024-12-03
Completion:: 2026-08-31

Conditions

Psychological Distress

Interventions

BEHAVIORAL

No Results Yet

NCT06487351 | NOT_YET_RECRUITING | NA

70 participants

Intervention to Reduce Implicit Bias in Pharmacies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2027-07-31
Completion:: 2029-01-31

Conditions

Bias, Implicit
HIV
Pre-exposure Prophylaxis

Interventions

BEHAVIORAL

No Results Yet

NCT06482437 | COMPLETED | PHASE2

81 participants

Safety and Efficacy of NMD670 in Adult Patients With Type 1 and Type 2 Charcot-Marie-Tooth Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2024-09-30
Completion:: 2025-10-28

Conditions

Charcot-Marie-Tooth Disease

Interventions

DRUG

No Results Yet

NCT06446531 | RECRUITING | PHASE1

64 participants

Prevention of Progression of Prediabetes, Obesity and CV Risk

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2024-09-11
Completion:: 2027-07-31

Conditions

Pre-Diabetes
Weight, Body
Cardiovascular Diseases

Interventions

DRUG

No Results Yet

NCT06418711 | TERMINATED | PHASE3

132 participants

ICoN-1 Phase 3 Study of the Efficacy and Safety of Treatment With MNKD-101, Clofazimine Inhalation Suspension

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2024-09-11
Completion:: 2025-11-10

Conditions

MAC Lung Disease
Treatment Refractory MAC Lung Disease
Mycobacterium Infections, Nontuberculous

Interventions

DRUG

No Results Yet

NCT06413173 | RECRUITING | NA

160 participants

Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2024-07-25
Completion:: 2028-09-30

Conditions

Brain Concussion
Brain Trauma
Attention Concentration Difficulty
Brain Injuries
Brain Injuries, Traumatic
Neurocognitive Dysfunction
Attention Impaired
Memory Impairment
Mild Traumatic Brain Injury
Mild Cognitive Impairment
Post Concussive Symptoms

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06364514 | RECRUITING | NA

50 participants

PICNIC Study - PatIent Centered aNtIbiotic Courses in Children With Medical Complexity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2024-08-20
Completion:: 2026-06-01

Conditions

Pneumonia

Interventions

OTHER

No Results Yet

NCT06351644 | TERMINATED | PHASE1/PHASE2

2 participants

ON 123300 (Narazaciclib) and Dexamethasone in Patients With Relapsed and/or Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2024-10-02
Completion:: 2025-04-28

Conditions

Relapsed and/or Refractory Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06257628 | WITHDRAWN

0 participants

MACE CDS Software Master Enrollment Protocol

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-12
Start Date:: 2023-09-14
Completion:: 2025-05-31

Conditions

Cardiac Events

Interventions

DEVICE

No Results Yet

NCT06191484 | RECRUITING | NA

169 participants

Risk and Resilience to Suicide Following Late-Life Spousal Bereavement

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2023-11-20
Completion:: 2028-12-31

Conditions

Suicide
Bereavement

Interventions

BEHAVIORAL

No Results Yet

NCT06189807 | ACTIVE_NOT_RECRUITING | NA

70 participants

Pregnancy and Contraception Education in Chronic Kidney Disease (PACE-CKD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2024-02-14
Completion:: 2025-09-24

Conditions

CKD
Chronic Kidney Diseases

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06133634 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

70 participants

Fisetin to Improve Vascular Function in Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-12
Start Date:: 2023-09-25
Completion:: 2026-03-31

Conditions

Aging
Endothelial Dysfunction
Arterial Stiffness

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet