Long-term Follow-up Study of Gene Therapy for Arrhythmogenic Cardiomyopathy Due to a Plakophilin-2 Pathogenic Variant
NCT07050160 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 10
Last updated 2025-11-12
Summary
The primary objective of this Phase 1/2 long-term follow-up (LTFU) study is to assess the long-term safety and tolerability of LX2020 for the treatment of arrhythmogenic cardiomyopathy (ACM) due to a plakophilin-2 gene (PKP2) pathogenic variant (PKP2-ACM).
Conditions
- Arrhythmogenic Cardiomyopathy
- PKP2-ACM
- PKP2-ARVC
Sponsors & Collaborators
-
Lexeo Therapeutics
lead INDUSTRY
Principal Investigators
-
Lexeo Clinical Trials · Lexeo Therapeutics
Eligibility
- Min Age
- 18 Years
- Max Age
- 67 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-08-29
- Primary Completion
- 2030-08-31
- Completion
- 2030-08-31
Countries
- United States
Study Locations
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