Clinical Trials Updated in 2025

NCT06093100 | RECRUITING

10 participants

Wearable Technology to Evaluate Hyperglycemia and HRV in DMD - Longitudinal Aim

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-06
Start Date:: 2024-07-10
Completion:: 2029-12-31

Conditions

Duchenne Muscular Dystrophy

Interventions

DEVICE

No Results Yet

NCT06091527 | RECRUITING | NA

180 participants

Treating Major Depression With Yoga Mono-therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2024-10-25
Completion:: 2026-06-30

Conditions

Depression Mild
Depression Moderate

Interventions

BEHAVIORAL

No Results Yet

NCT06071377 | RECRUITING

1000 participants

Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-06
Start Date:: 2023-04-01
Completion:: 2026-12-31

Conditions

Sickle Cell Trait

Interventions

OTHER

No Results Yet

NCT06031259 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

6 participants

Extension Study of Idursulfase-IT Along With Elaprase in Children and Adults With Hunter Syndrome and Cognitive Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2024-03-05
Completion:: 2029-01-01

Conditions

Hunter Syndrome

Interventions

DRUG

No Results Yet

NCT05985291 | TERMINATED

6 participants

BurstDR Stimulation for Painful Diabetic Neuropathy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-06
Start Date:: 2023-07-03
Completion:: 2025-10-06

Conditions

Painful Diabetic Neuropathy

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05984784 | TERMINATED | PHASE1/PHASE2

13 participants

A Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of IMG-007 in Adults With Atopic Dermatitis (AD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2023-08-09
Completion:: 2024-04-26

Conditions

Atopic Dermatitis
Moderate-to-severe Atopic Dermatitis
AD

Interventions

DRUG

Results Available

NCT05981508 | COMPLETED | NA

21 participants

Online Family Dyadic Skills Training for Black Adults in Behavioral Weight Loss Program

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2024-02-05
Completion:: 2024-08-30

Conditions

Body Weight
Body Weight Changes
Obesity
Overweight and Obesity
Overweight
Behavior, Eating
Physical Inactivity
Chronic Disease
Weight Loss
Weight Reduction

Interventions

BEHAVIORAL

Results Available

NCT05943496 | RECRUITING | PHASE1

27 participants

Tafasitamab, Acalabrutinib, and Obinutuzumab for the Treatment of Previously Untreated Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2023-10-02
Completion:: 2027-01-01

Conditions

Chronic Lymphocytic Leukemia

Interventions

DRUG
PROCEDURE
BIOLOGICAL
OTHER

No Results Yet

NCT05939700 | RECRUITING

20 participants

Mavacamten Pregnancy Surveillance Program

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-06
Start Date:: 2023-11-09
Completion:: 2027-04-30

Conditions

Breastfeeding
Hypertrophic Cardiomyopathy
Pregnancy Related

Interventions

DRUG

No Results Yet

NCT05869552 | RECRUITING | NA

1485 participants

Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2023-07-13
Completion:: 2027-03-31

Conditions

Suicide
Suicidal Ideation

Interventions

OTHER

No Results Yet

NCT05824702 | COMPLETED | NA

241 participants

A Social Network Approach for Improving Medication Assisted Treatment and HIV Prevention and Medical Care Among People Who Inject Drugs in Ukraine

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2023-09-20
Completion:: 2025-09-01

Conditions

HIV

Interventions

BEHAVIORAL

No Results Yet

NCT05804383 | COMPLETED | PHASE1

51 participants

A Multiple Ascending Dose Study in Healthy Volunteers and Patients With Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2023-03-28
Completion:: 2025-07-15

Conditions

Alzheimer's Disease

Interventions

DRUG

No Results Yet

NCT05798611 | TERMINATED | PHASE2

36 participants

Study of ART0380 in Patients With Biologically Selected Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2023-09-06
Completion:: 2024-11-15

Conditions

Advanced Solid Tumor
Recurrent Endometrial Cancer
Metastatic Cancer

Interventions

DRUG

No Results Yet

NCT05756088 | WITHDRAWN

0 participants

Determining the Association of Microvascular Disease as Assessed by PET and Graft Injury by Donor Derived Cell Free DNA

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-06
Start Date:: 2025-12-31
Completion:: 2030-06-30

Conditions

Cardiac Allograft Vasculopathy
Endothelial Dysfunction
Microvascular Coronary Artery Disease

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05681715 | COMPLETED | PHASE3

62 participants

A Phase 3, Open-label, Crossover Study to Evaluate Self-administration of Rozanolixizumab by Study Participants With Generalized Myasthenia Gravis (gMG)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2023-04-17
Completion:: 2024-04-23

Conditions

Generalized Myasthenia Gravis

Interventions

DRUG

Results Available

NCT05623774 | COMPLETED | PHASE1

64 participants

A Dose Calibration Study Comparing IkT-001Pro to Imatinib Mesylate 400mg

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2022-12-16
Completion:: 2024-06-30

Conditions

CML

Interventions

DRUG

No Results Yet

NCT05474846 | RECRUITING | PHASE2/PHASE3

188 participants

Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2022-11-21
Completion:: 2027-02-28

Conditions

Sleep
Fatigue
Anxiety
Cancer
Depression

Interventions

DRUG
OTHER

No Results Yet

NCT05455684 | COMPLETED | PHASE3

513 participants

A Study of Aticaprant as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2022-06-22
Completion:: 2024-09-18

Conditions

Depressive Disorder, Major
Anhedonia

Interventions

DRUG
OTHER

Results Available

NCT05445466 | COMPLETED | NA

14 participants

Causal Lesion Network Guided Treatment of Bipolar Mania With Transcranial Electrical Stimulation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2022-12-16
Completion:: 2025-06-01

Conditions

Bipolar Disorder
Schizo Affective Disorder

Interventions

DEVICE

Results Available

NCT05405660 | COMPLETED | PHASE2

196 participants

A Study of CDX-0159 in Patients With Chronic Inducible Urticaria

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2022-06-28
Completion:: 2024-06-12

Conditions

Chronic Inducible Urticaria

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT05330078 | COMPLETED | EARLY_PHASE1

10 participants

Examining the Therapeutic Potential of Botulinum Toxin Type A in the Treatment of Keloids

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2022-03-11
Completion:: 2023-05-31

Conditions

Keloid

Interventions

DRUG

No Results Yet

NCT05268107 | RECRUITING | PHASE4

30 participants

Ethnic Differences in Mechanisms of Action of Dupilumab

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2023-01-25
Completion:: 2026-12-31

Conditions

Atopic Dermatitis

Interventions

DRUG

No Results Yet

NCT05252390 | TERMINATED | PHASE1

82 participants

NUV-868 as Monotherapy and in Combination With Olaparib or Enzalutamide in Adult Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2022-03-29
Completion:: 2024-07-15

Conditions

Advanced Solid Tumor
Ovarian Cancer
Ovary Cancer
Cancer of Ovary
Cancer of the Ovary
Ovary Neoplasm
Pancreatic Cancer
Pancreas Cancer
Cancer of Pancreas
Cancer of the Pancreas
Pancreas Neoplasm
Prostate Cancer
Prostatic Cancer
Cancer of Prostate
Cancer of the Prostate
Prostate Neoplasm
Castrate Resistant Prostate Cancer
Castration Resistant Prostatic Cancer
Castration Resistant Prostatic Neoplasms
Triple-negative Breast Cancer
Triple Negative Breast Cancer
Triple Negative Breast Neoplasms
Breast Cancer
Breast Carcinoma
Cancer of Breast
Cancer of the Breast
Breast Tumor

Interventions

DRUG

No Results Yet

NCT05245903 | RECRUITING

40 participants

Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-06
Start Date:: 2022-05-31
Completion:: 2026-05-31

Conditions

Alzheimer Disease
Dementia Alzheimers
Dementia
Cognitive Impairment
Mild Cognitive Impairment
Neurodegenerative Diseases
Neurocognitive Disorders
Neurocognitive Dysfunction
Cognitive Dysfunction
Mental Disorder

Interventions

DEVICE

No Results Yet

NCT05204563 | COMPLETED | PHASE3

450 participants

Imipenem/Cilastatin-XNW4107 Versus Imipenem/Cilastatin/Relebactam for Treatment of Participants With Bacterial Pneumonia (XNW4107-302, REITAB-2)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2022-07-31
Completion:: 2024-09-29

Conditions

Hospital Acquired Bacterial Pneumonia or Ventilator-Associated Bacterial Pneumonia

Interventions

DRUG

Results Available

NCT05166590 | COMPLETED | NA

77 participants

Sleep and Social Experiences Study 2

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2021-06-01
Completion:: 2025-05-31

Conditions

Sleep
Blood Pressure

Interventions

BEHAVIORAL

No Results Yet

NCT05126355 | ACTIVE_NOT_RECRUITING | NA

529 participants

Effectiveness of the On the Move Group Exercise Program to Improve Mobility in Community-dwelling Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2022-06-23
Completion:: 2025-09-18

Conditions

Mobility Limitation

Interventions

BEHAVIORAL

No Results Yet

NCT05125237 | COMPLETED

155963 participants

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Amiloride vs Triamterene

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-06
Start Date:: 2021-10-01
Completion:: 2023-07-07

Conditions

Hypertension

Interventions

DRUG

Results Available

NCT05125224 | COMPLETED

163720 participants

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Dihydropyridine Calcium Channel Blockers Versus Hydrochlorothiazide

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-06
Start Date:: 2021-10-01
Completion:: 2023-07-07

Conditions

Hypertension

Interventions

DRUG

Results Available

NCT05116241 | COMPLETED | PHASE2

368 participants

Immunogenicity and Safety of BPZE1 Intranasal Pertussis Vaccine in Healthy School-age Children

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2021-11-11
Completion:: 2024-05-15

Conditions

Bordetella Pertussis, Whooping Cough

Interventions

BIOLOGICAL

Results Available

NCT05078190 | ACTIVE_NOT_RECRUITING

200 participants

Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Breast Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-06
Start Date:: 2021-10-21
Completion:: 2039-10-31

Conditions

Breast Cancer
Cardiotoxicity
Drug-Related Side Effects and Adverse Reactions
Cardiovascular Diseases

Interventions

OTHER

No Results Yet

NCT05074303 | COMPLETED | PHASE2

78 participants

Beta-glucan and Immune Response to Influenza Vaccine

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2022-07-18
Completion:: 2024-03-01

Conditions

Healthy Aging

Interventions

BIOLOGICAL
DIETARY_SUPPLEMENT

Results Available

NCT05012943 | COMPLETED | PHASE2/PHASE3

19474 participants

The ARCT-154 Self-Amplifying RNA Vaccine Efficacy Study (ARCT-154-01)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2021-08-15
Completion:: 2023-01-18

Conditions

COVID-19 Vaccines

Interventions

BIOLOGICAL
OTHER

Results Available

NCT04883463 | RECRUITING | NA

12 participants

Neuromodulation to Improve Respiratory Function in Cervical Spinal Cord Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2021-09-27
Completion:: 2027-12-31

Conditions

Spinal Cord Injuries

Interventions

DEVICE

No Results Yet

NCT04755283 | ACTIVE_NOT_RECRUITING | PHASE2

1287 participants

Safety and Tolerability of Abelacimab (MAA868) vs. Rivaroxaban in Patients With Atrial Fibrillation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2021-02-02
Completion:: 2024-02-15

Conditions

Atrial Fibrillation (AF)
Stroke

Interventions

BIOLOGICAL
DRUG

Results Available

NCT04742439 | WITHDRAWN | NA

0 participants

Individualizing tDCS Dose

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2024-12-02
Completion:: 2024-12-02

Conditions

tDCS
Motor Function

Interventions

DEVICE

No Results Yet

NCT04729062 | APPROVED_FOR_MARKETING

C3G/Primary IC-MPGN EAP

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-11-06

Conditions

C3G
IC-MPGN
C3 Glomerulopathy
C3 Glomerulonephritis
Complement 3 Glomerulopathy
Complement 3 Glomerulopathy (C3G)
Complement 3 Glomerulonephritis
Dense Deposit Disease
DDD
Membranoproliferative Glomerulonephritis
Membranoproliferative Glomerulonephritis (MPGN)
Immune Complex Membranoproliferative Glomerulonephritis (IC-MPGN)

Interventions

DRUG

No Results Yet

NCT04584294 | COMPLETED | NA

465 participants

Patient-Centered Reproductive Decision Support Tool for Women Veterans

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2021-03-01
Completion:: 2024-08-30

Conditions

Contraception
Contraception Behavior
Prepregnancy Health
Reproductive Health

Interventions

BEHAVIORAL

Results Available

NCT04550845 | RECRUITING | NA

90 participants

Understanding of Genetics by Men at Risk for Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2023-05-01
Completion:: 2027-09-27

Conditions

Prostate Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT04544735 | ACTIVE_NOT_RECRUITING | NA

12 participants

Improving Women's Function After Pelvic Radiation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-06
Start Date:: 2020-10-07
Completion:: 2026-05-31

Conditions

Sexual Dysfunction
Pelvic Floor Disorders
Gynecologic Cancer

Interventions

BEHAVIORAL

No Results Yet