Clinical Trials Updated in 2025

NCT06223373 | TERMINATED | NA

3 participants

Blood Flow Restriction Therapy Following Acute Shoulder Injury Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2024-04-13
Completion:: 2024-10-18

Conditions

Shoulder Injury

Interventions

DEVICE

Results Available

NCT06150781 | RECRUITING

2842 participants

Aimovig Pregnancy Exposure Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-04
Start Date:: 2021-01-27
Completion:: 2027-10-28

Conditions

Migraine

Interventions

DRUG

No Results Yet

NCT06148636 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

24 participants

A Safety Study of 212Pb-VMT-alpha-NET in Patients With Neuroendocrine Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2023-11-10
Completion:: 2026-12-31

Conditions

Neuroendocrine Tumors
Neuroendocrine Tumor of the Lung
Neuroendocrine Tumor Grade 1
Neuroendocrine Tumor Grade 2
Neuroendocrine Tumor of Pancreas

Interventions

DRUG
DIAGNOSTIC_TEST

No Results Yet

NCT05964413 | TERMINATED | PHASE3

54 participants

Phase III Trial to Investigate Efficacy and Safety of Vilobelimab in Ulcerative Pyoderma Gangrenosum

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2023-11-01
Completion:: 2025-07-11

Conditions

Pyoderma Gangrenosum

Interventions

DRUG

No Results Yet

NCT05906368 | COMPLETED | NA

34 participants

Hypotension Prediction Index to Predict Epidural-labor Analgesia Induced Hypotension

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2024-04-18
Completion:: 2024-08-29

Conditions

Anesthesia, Epidural
Hypotension

Interventions

DIAGNOSTIC_TEST

Results Available

NCT05902988 | RECRUITING | PHASE1/PHASE2

200 participants

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2023-10-18
Completion:: 2026-06-30

Conditions

Advanced Solid Tumor
High Grade Serous Adenocarcinoma of Ovary
Squamous Non-small-cell Lung Cancer
Triple Negative Breast Cancer
Head and Neck Squamous Cell Carcinoma
Ovarian Carcinosarcoma
Uterine Carcinosarcoma
Uterine Serous Carcinoma
Endometrium Cancer
Chromosomal Instability

Interventions

DRUG

No Results Yet

NCT05894655 | COMPLETED | NA

6527 participants

Community-engaged Optimization of COVID-19 Rapid Evaluation And TEsting Experiences

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2023-08-28
Completion:: 2025-03-31

Conditions

COVID-19
COVID-19 Pandemic

Interventions

BEHAVIORAL

No Results Yet

NCT05809596 | COMPLETED | NA

949 participants

HEAL-LAA Clinical Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2023-10-03
Completion:: 2024-07-15

Conditions

Stroke
Bleeding
Atrial Fibrillation

Interventions

DEVICE

Results Available

NCT05774197 | COMPLETED | NA

52 participants

Psychological Intervention Using Smartphone Technology to Alleviate Malignant Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2023-05-04
Completion:: 2024-09-24

Conditions

Cancer Pain
Opioid Use
Cognitive Behavior Therapy

Interventions

BEHAVIORAL

Results Available

NCT05725395 | COMPLETED | NA

158 participants

Virtual Reality as a Intrinsic Motivation Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2023-06-20
Completion:: 2025-01-30

Conditions

Psychological

Interventions

BEHAVIORAL

No Results Yet

NCT05723523 | COMPLETED | NA

3230 participants

A Technology-Driven Intervention to Improve Early Detection and Management of Cognitive Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2023-08-23
Completion:: 2025-08-31

Conditions

Dementia
Cognitive Impairment

Interventions

OTHER

No Results Yet

NCT05717153 | RECRUITING | EARLY_PHASE1

18 participants

Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade Glioma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2023-10-01
Completion:: 2027-01-15

Conditions

Diffuse Glioma
Malignant Glioma

Interventions

PROCEDURE
DRUG
DEVICE

No Results Yet

NCT05677633 | COMPLETED | PHASE1

11 participants

Biomarker Validation Following Sargramostim Treatment in Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2023-01-19
Completion:: 2024-04-12

Conditions

Parkinson's Disease and Parkinsonism

Interventions

DRUG

No Results Yet

NCT05616819 | RECRUITING | NA

480 participants

Effect of Morning Light Exposure on Mood

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2023-07-01
Completion:: 2026-01-01

Conditions

Suicidal Ideation
Regulation, Emotion

Interventions

OTHER

No Results Yet

NCT05608499 | TERMINATED | PHASE3

15 participants

Duobrii Treatment of Acne Keloidalis Nuchae (AKN)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2022-10-26
Completion:: 2024-04-15

Conditions

Acne Keloidalis Nuchae
AKN

Interventions

DRUG

Results Available

NCT05600764 | RECRUITING

70 participants

The Natural History of TRPV4 Neuropathy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-04
Start Date:: 2023-12-15
Completion:: 2033-12-31

Conditions

TRPV4 Gene Mutation

No Results Yet

NCT05588934 | RECRUITING | NA

180 participants

Caffeine Optimization Versus Standard Caffeine Dosage (2B-2)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2023-06-09
Completion:: 2026-03-31

Conditions

Sleep Deprivation
Caffeine

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT05574114 | ACTIVE_NOT_RECRUITING | PHASE1

20 participants

A Study of Radiation Therapy Before CAR T Cell Therapy for People With B Cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2022-10-05
Completion:: 2026-10-31

Conditions

Non-Hodgkin Lymphoma
Non-Hodgkin's Lymphoma, Relapsed
Non-Hodgkin's Lymphoma Refractory

Interventions

RADIATION
DRUG
BIOLOGICAL

No Results Yet

NCT05568927 | COMPLETED

150 participants

Validation of SEARCH, a Novel Hierarchical Algorithm to Define Long-term Outcomes After Pulmonary Embolism

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-04
Start Date:: 2022-11-15
Completion:: 2025-06-13

Conditions

Pulmonary Embolism
Chronic Thromboembolic Pulmonary Hypertension

Interventions

OTHER

No Results Yet

NCT05456503 | RECRUITING | PHASE3

72 participants

PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using [18F]-PI-2620

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2022-09-19
Completion:: 2028-08-31

Conditions

Frontotemporal Lobar Degeneration
Alzheimer Disease
Cognitively Normal

Interventions

DRUG

No Results Yet

NCT05453110 | COMPLETED | NA

903 participants

Does Self-efficacy Predict Outcomes Among U.S. Military Academy Cadets During Initial Entry Training?

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2022-07-04
Completion:: 2022-08-02

Conditions

Low Back Pain
Musculoskeletal Injury

Interventions

BEHAVIORAL

Results Available

NCT05443659 | COMPLETED

1629 participants

Real-world Data Analysis of REN Treatment in Adolescence With Migraine

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-04
Start Date:: 2021-01-01
Completion:: 2022-05-31

Conditions

Migraine in Adolescence

Interventions

DEVICE

Results Available

NCT05424757 | COMPLETED

158 participants

Polyethylene Glycol Safety in Children

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-04
Start Date:: 2022-09-30
Completion:: 2025-08-09

Conditions

Polyethylene Glycols
Children, Only

Interventions

DRUG

No Results Yet

NCT05380947 | COMPLETED | PHASE1

13 participants

A Study in Healthy Men to Compare Two Different Oral Formulations of BI 1810631 and to Test How Food or Rabeprazole Influence the Amount of BI 1810631 in the Blood

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2022-06-23
Completion:: 2022-09-13

Conditions

Healthy

Interventions

DRUG

Results Available

NCT05378386 | ACTIVE_NOT_RECRUITING

150 participants

ALTERRA Post-Approval Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-04
Start Date:: 2022-05-12
Completion:: 2025-09-25

Conditions

Pulmonary Valve Insufficiency
Complex Congenital Heart Defect
Tetralogy of Fallot
Pulmonary Regurgitation
RVOT Anomaly

Interventions

DEVICE

No Results Yet

NCT05344508 | APPROVED_FOR_MARKETING

An Expanded Access Study to Assess Brensocatib for Participants With Non-Cystic Fibrosis Bronchiectasis

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-11-04

Conditions

Non-Cystic Fibrosis Bronchiectasis

Interventions

DRUG

No Results Yet

NCT05342545 | COMPLETED | NA

400 participants

Decision Support for Detection of Chronic Kidney Disease in Type II Diabetes Mellitus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2022-12-01
Completion:: 2024-12-31

Conditions

Chronic Kidney Diseases
Type2Diabetes

Interventions

OTHER

No Results Yet

NCT05256394 | COMPLETED | NA

39 participants

Patient-Centered Chronic Pain Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2025-01-13
Completion:: 2025-08-31

Conditions

Chronic Pain
Opioid Use
Musculoskeletal Pain

Interventions

BEHAVIORAL

No Results Yet

NCT05152888 | RECRUITING | PHASE4

50 participants

The Impact of Pcsk-9 Inhibition on PET CFR in Patients at High CV Risk

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2022-03-03
Completion:: 2027-03-31

Conditions

Stable Coronary Disease

Interventions

DRUG

No Results Yet

NCT05103384 | COMPLETED

15 participants

Utilizing Neural Signatures and Virtual Reality to Advance DBS Programming

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-04
Start Date:: 2022-07-22
Completion:: 2024-06-24

Conditions

Parkinson Disease
DBS
Deep Brain Stimulation
Freezing of Gait
Virtual Reality

Interventions

OTHER

Results Available

NCT05100472 | ACTIVE_NOT_RECRUITING | PHASE2

50 participants

A Study of Shorter Course Hormone Therapy and Radiation for High-risk Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2021-10-19
Completion:: 2026-10-19

Conditions

Prostate Cancer

Interventions

BIOLOGICAL
RADIATION

No Results Yet

NCT05081479 | ACTIVE_NOT_RECRUITING | PHASE1

9 participants

A Study of N-Acetylcysteine (N-AC) in People Receiving CAR T-cell Therapy for Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2021-12-08
Completion:: 2026-10-21

Conditions

Lymphoma

Interventions

DRUG

No Results Yet

NCT05048485 | COMPLETED

141 participants

Tuberculosis - Learning the Effect of Parasites and Reinforcing Diets

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-04
Start Date:: 2022-04-09
Completion:: 2025-07-21

Conditions

Tuberculosis, Pulmonary
Helminthiasis
Malnutrition

No Results Yet

NCT05002218 | COMPLETED | NA

64 participants

Training in Ataxia - Individuals With Degenerative Cerebellar Diseases

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2022-01-31
Completion:: 2024-11-06

Conditions

Cerebellar Ataxia

Interventions

BEHAVIORAL

Results Available

NCT05000996 | RECRUITING

300 participants

Gut Microbiota in Metabolic Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-04
Start Date:: 2021-08-19
Completion:: 2028-12-31

Conditions

Bariatric Surgery Candidate
Cardiovascular Diseases
Type 2 Diabetes
Dyslipidemias
Hypertension
Morbid Obesity

Interventions

PROCEDURE

No Results Yet

NCT04975464 | ACTIVE_NOT_RECRUITING

600 participants

BRINK (BRain In Kidney Disease) Memory Study 2.0

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-04
Start Date:: 2011-11-15
Completion:: 2026-05-31

Conditions

Chronic Kidney Diseases
Dementia
Dementia, Vascular
Stroke
Alzheimer Disease
Cognitive Decline
Cognitive Impairment
Cognitive Dysfunction
Kidney Diseases
Diabetes
Cerebral Atrophy
Small Vessel Ischemic Disease

No Results Yet

NCT04968548 | ACTIVE_NOT_RECRUITING

5000 participants

Determination and Validation of a Multi-analyte Assay for Lung Cancer Screening

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-04
Start Date:: 2021-09-17
Completion:: 2025-12-31

Conditions

Lung Cancer

Interventions

PROCEDURE

No Results Yet

NCT04958785 | TERMINATED | PHASE2

92 participants

Study of Magrolimab Combination Therapy in Patients With Non-Surgically Removable Locally Advanced or Metastatic Triple-Negative Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2021-12-14
Completion:: 2024-10-08

Conditions

Triple-Negative Breast Cancer

Interventions

DRUG

Results Available

NCT04898231 | COMPLETED | PHASE2/PHASE3

73 participants

MIS-C Comparative Effectiveness Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2020-12-22
Completion:: 2023-12-22

Conditions

Multisystem Inflammatory Syndrome-Children

Interventions

DRUG

Results Available

NCT04869917 | ACTIVE_NOT_RECRUITING | NA

960 participants

Behavioral Nudges for Diabetes Prevention (BEGIN) Trial in Primary Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-04
Start Date:: 2022-03-21
Completion:: 2025-09-01

Conditions

PreDiabetes

Interventions

BEHAVIORAL

No Results Yet