Clinical Trials Updated in 2025

NCT04073225 | COMPLETED | NA

23 participants

Optimizing Cognitive, Environmental, and Neuromotor Stimulation in Traumatic Brain Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2020-01-25
Completion:: 2024-09-03

Conditions

Traumatic Brain Injury
Dementia Alzheimers
Military Activity

Interventions

DEVICE
BEHAVIORAL

Results Available

NCT04057209 | RECRUITING | NA

34 participants

VoiceS: Voice Quality After Transoral CO2-Laser Surgery Versus Single Vocal Cord Irradiation for Larynx Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2019-11-20
Completion:: 2027-11-30

Conditions

Glottis Tumor
Larynx Cancer

Interventions

RADIATION
PROCEDURE

No Results Yet

NCT03943511 | TERMINATED | NA

25 participants

Discharged With Indwelling Chest Tube and Valve

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2019-10-07
Completion:: 2023-11-20

Conditions

Prolonged Air Leak

Interventions

OTHER

No Results Yet

NCT03930251 | SUSPENDED | NA

117 participants

Cognitive Remediation for Coordinated Specialty Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2019-06-01
Completion:: 2023-10-31

Conditions

Schizophrenia
Schizoaffective Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT03901469 | TERMINATED | PHASE2

115 participants

A Study of ZEN003694 and Talazoparib in Patients With Triple Negative Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2019-06-26
Completion:: 2024-03-07

Conditions

Triple Negative Breast Cancer

Interventions

DRUG

Results Available

NCT03892967 | COMPLETED | NA

50207 participants

Enhanced, EHR-facilitated Cancer Symptom Control Pragmatic Clinical Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2019-03-28
Completion:: 2023-01-31

Conditions

Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm

Interventions

OTHER

Results Available

NCT03776812 | COMPLETED | PHASE2

178 participants

Study of Relacorilant in Combination With Nab-Paclitaxel for Patients With Recurrent Platinum-Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2019-04-05
Completion:: 2021-03-16

Conditions

Recurrent Ovarian Cancer
Recurrent Fallopian Tube Carcinoma
Recurrent Primary Peritoneal Carcinoma

Interventions

DRUG

Results Available

NCT03737370 | COMPLETED | PHASE1

43 participants

Fractionated Docetaxel and Radium 223 in Metastatic Castration-Resistant Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2018-01-30
Completion:: 2024-12-31

Conditions

Metastatic Castrate Resistant Prostate Cancer

Interventions

DRUG
RADIATION

No Results Yet

NCT03704389 | COMPLETED | NA

664 participants

Behavioral Economics Applications to Geriatrics Leveraging EHRs

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2019-01-17
Completion:: 2019-07-17

Conditions

Prostate Specific Antigen
Asymptomatic Bacteriuria
Type 2 Diabetes Mellitus

Interventions

BEHAVIORAL

Results Available

NCT03646214 | RECRUITING | NA

20 participants

Improving Sleep Quality During Pregnancy Using an Oral Appliance

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2018-02-01
Completion:: 2026-04-30

Conditions

Snoring
Sleep Fragmentation

Interventions

DEVICE

No Results Yet

NCT03603899 | COMPLETED | PHASE1/PHASE2

3 participants

Hp129 Xenon Imaging and BOS in Lung Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2020-09-09
Completion:: 2024-05-28

Conditions

Bronchiolitis Obliterans

Interventions

DRUG

No Results Yet

NCT03564691 | COMPLETED | PHASE1

470 participants

Study of MK-4830 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-4830-001)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2018-07-11
Completion:: 2025-09-26

Conditions

Neoplasms

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT03383094 | ACTIVE_NOT_RECRUITING | PHASE2

126 participants

Chemoradiation vs Immunotherapy and Radiation for Head and Neck Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2018-03-15
Completion:: 2026-12-31

Conditions

Head and Neck Squamous Cell Carcinoma
Cancer
Cancer of Head and Neck
Cancer, Advanced
Cancer, Metastatic
Tumor
Tumor Recurrence
Tumor Neck
Tumor Metastasis
Oral Cancer
Oropharyngeal Cancer
Oropharynx Cancer
Oropharynx Cancer, Stage III
Oropharynx Cancer, Recurrent
Oropharynx Cancer, Metastatic

Interventions

DRUG
RADIATION

No Results Yet

NCT03306173 | COMPLETED | NA

142 participants

COMET Study 1: Filter Ventilated Cigarette Substitution in the ETM

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2018-08-08
Completion:: 2020-03-10

Conditions

Substance-Related Disorders

Interventions

OTHER

Results Available

NCT03245541 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

18 participants

Radiation Therapy in Combination With Durvalumab for People With Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2020-08-14
Completion:: 2026-09-30

Conditions

Pancreatic Adenocarcinoma

Interventions

DRUG
RADIATION

No Results Yet

NCT03217058 | COMPLETED | NA

10821 participants

Computerized Substance Use and Depression Screening and Behavioral Treatment in HIV Primary Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2016-08-01
Completion:: 2020-07-31

Conditions

Substance Use Disorders
HIV
Depression
Anxiety

Interventions

BEHAVIORAL

Results Available

NCT03033303 | COMPLETED | PHASE2

59 participants

A Study of the Effect of Hu3F8/GM-CSF Immunotherapy Plus Isotretinoin in Patients in First Remission of High-Risk Neuroblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2017-01-23
Completion:: 2025-09-29

Conditions

Neuroblastoma

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT03019471 | RECRUITING

40 participants

Non Invasive Cancer Test (NICT): a Proof of Principle Study.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-07
Start Date:: 2016-03-01
Completion:: 2025-12-31

Conditions

Neoplasmata

Interventions

GENETIC

No Results Yet

NCT02970617 | COMPLETED | NA

82 participants

Ringing a Bell on the Final Day of Radiation Therapy in Improving the Memory of Distress in Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2016-08-15
Completion:: 2018-11-15

Conditions

Distress
Malignant Neoplasm

Interventions

OTHER

No Results Yet

NCT02969746 | WITHDRAWN | PHASE4

0 participants

Activates Charcoal for Patients Undergoing Invasive Procedure Delayed Due to Direct Oral Anticoagulants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2014-07-18
Completion:: 2018-09-30

Conditions

Anticoagulants; Circulating, Hemorrhagic Disorder

Interventions

DRUG

No Results Yet

NCT02917798 | ACTIVE_NOT_RECRUITING

1047 participants

Evaluating an Alternative Clinical Genetics Cancer Care Delivery Model: A Pilot Study of Patient Outcomes

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-07
Start Date:: 2016-07-12
Completion:: 2026-09-30

Conditions

Ovarian Cancer
Prostate Cancer
Pancreas Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT02879812 | COMPLETED | NA

56332 participants

Disparities in National Kidney Allocation Policy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2016-09-30
Completion:: 2019-08-02

Conditions

Kidney Disorders

Interventions

OTHER

Results Available

NCT02621151 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

Pembrolizumab (MK3475), Gemcitabine, and Concurrent Hypofractionated Radiation Therapy for Muscle-Invasive Urothelial Cancer of the Bladder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2016-08-11
Completion:: 2022-11-10

Conditions

Muscle-invasive Urothelial Cancer of the Bladder

Interventions

BIOLOGICAL
PROCEDURE
DRUG
RADIATION

Results Available

NCT02586207 | COMPLETED | PHASE1

59 participants

Pembrolizumab in Combination With CRT for LA-SCCHN

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2015-11-30
Completion:: 2020-09-29

Conditions

Head and Neck Cancer
Squamous Cell Carcinoma
Oral Cavity Cancer
Oropharynx Cancer
Hypopharynx Cancer
Larynx Cancer
Laryngeal Cancer

Interventions

DRUG
RADIATION

Results Available

NCT02355184 | TERMINATED | PHASE2

20 participants

An Extension of Protocol PRO 140_CD01 Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2014-11-18
Completion:: 2022-06-30

Conditions

HIV
Human Immunodeficiency Virus

Interventions

DRUG

Results Available

NCT02285439 | COMPLETED | PHASE1/PHASE2

105 participants

Study of MEK162 for Children With Low-Grade Gliomas

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2016-05-04
Completion:: 2022-11-02

Conditions

Low-Grade Gliomas
Malignant Neoplasms, Brain
Soft Tissue Neoplasms

Interventions

DRUG

Results Available

NCT02219659 | COMPLETED | NA

90 participants

Pilot Study on Pairing Sedation Strategies and Weaning

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2014-12-31
Completion:: 2017-05-31

Conditions

Acute Respiratory Failure

Interventions

DRUG

Results Available

NCT02178410 | ACTIVE_NOT_RECRUITING | PHASE3

25119 participants

VITAL Rhythm Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2012-10-31
Completion:: 2026-10-31

Conditions

Cardiovascular Disease

Interventions

DIETARY_SUPPLEMENT
DRUG

No Results Yet

NCT01861821 | COMPLETED | NA

650 participants

Analgesic Efficacy of a Multiport Versus Uniport Flexible Catheter for Labor Epidural Analgesia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2011-11-30
Completion:: 2013-06-30

Conditions

Labor Pain

Interventions

DEVICE

No Results Yet

NCT01271842 | COMPLETED

38 participants

Long-term Outcome and Lung Capacity in Survivors of ARDS Due to Influenza A (H1N1) v2009 The RESPIFLU Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-07
Start Date:: 2010-10-31
Completion:: 2011-10-02

Conditions

Influenza
Pneumonia, Viral
Pulmonary Fibrosis
Quality of Life
Stress Disorders, Post Traumatic

No Results Yet

NCT01203085 | COMPLETED

500 participants

Development of Charcot Marie Tooth Disease (CMT) Pediatric Scale for Children With CMT

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-07
Start Date:: 2010-04-30
Completion:: 2025-07-31

Conditions

Charcot Marie Tooth Disease

No Results Yet

NCT01193088 | RECRUITING

1050 participants

Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-07
Start Date:: 2010-05-31
Completion:: 2026-12-31

Conditions

Charcot-Marie-Tooth Disease, Type Ia (Disorder)
HMSN

No Results Yet

NCT01193075 | RECRUITING

5000 participants

Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-07
Start Date:: 2010-04-01
Completion:: 2026-12-31

Conditions

Charcot Marie Tooth Disease

No Results Yet

NCT01147445 | COMPLETED | PHASE1

36 participants

Phase I Study of ETEC Vaccine

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-07
Start Date:: 2010-09-13
Completion:: 2012-06-08

Conditions

Gastroenteritis Escherichia Coli

Interventions

BIOLOGICAL

No Results Yet

NCT01114269 | ACTIVE_NOT_RECRUITING

5764 participants

PRE-DETERMINE Cohort Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-07
Start Date:: 2007-07-31
Completion:: 2026-11-30

Conditions

Coronary Artery Disease
Left Ventricular Dysfunction
Sudden Cardiac Death

No Results Yet

NCT01095744 | COMPLETED

60 participants

Influence of Age on Amyloid Load in Alzheimer's Disease and in Atypical Focal Cortical Alzheimer's Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-07
Start Date:: 2009-03-31
Completion:: 2012-05-31

Conditions

Alzheimer's Disease
Posterior Cortical Atrophy
Logopenic Progressive Aphasia

No Results Yet

NCT00064558 | COMPLETED

2500 participants

Genetic Determinants of Sudden Cardiac Death

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-07
Start Date:: 2003-07-31
Completion:: 2008-06-30

Conditions

Cardiovascular Diseases
Heart Diseases
Death, Sudden, Cardiac
Ventricular Arrhythmia
Arrhythmia

No Results Yet

NCT00031408 | ACTIVE_NOT_RECRUITING

17444 participants

Consent for Use of Stored Patient Specimens for Future Testing

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-07
Start Date:: 2002-02-13
Completion:: 2027-12-31

Conditions

HIV Infections

No Results Yet

NCT07209306 | RECRUITING | NA

237 participants

WHO Psychological Interventions for Mental Health Outcomes in Migrants Resettled in Italy: the ADVANCE Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2025-04-09
Completion:: 2026-11-30

Conditions

Distress, Psychological
Distress, Emotional

Interventions

OTHER

No Results Yet

NCT07209163 | NOT_YET_RECRUITING | PHASE1/PHASE2

48 participants

Combination Therapy With Tazemetostat in Relapsed and Refractory Peripheral T-cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2025-10-31
Completion:: 2026-03-31

Conditions

Peripheral T Cell Lymphoma

Interventions

DRUG

No Results Yet