Trial Outcomes & Findings for COMET Study 1: Filter Ventilated Cigarette Substitution in the ETM (NCT NCT03306173)
NCT ID: NCT03306173
Last Updated: 2025-10-07
Results Overview
Participants completed purchasing trials in an experimental marketplace, a virtual store designed to mimic real-world shopping environments. In each lab session, participants completed multiple trials in which the price of their assigned cigarette increased progressively from $0.13 in the first trial to $4.00 in the final trial, while prices for other products (e-cigarettes, e-liquid, nicotine gum, snus, lozenges, and dip) remained constant. The mean and standard deviation of quantity purchased in each trial were calculated for all prices and sessions 1, 2, and 3.
Recruitment status
COMPLETED
Study phase
NA
Target enrollment
142 participants
Primary outcome timeframe
Week 2 (Session 1), Week 6 (Sessions 2), Week 10 (Session 3)
Results posted on
2025-10-07
Participant Flow
The number of participants enrolled differs from those who started the study because, after providing informed consent, participants submitted a breath carbon monoxide (CO) sample to assess recent cigarette use. Participants were excluded from the study if their CO level was below 8 ppm, indicating no recent smoking. They consented and were assigned to an arm/group, however, they didn't begin the intervention they were assigned to.
Participant milestones
| Measure |
Ventilated Cigarettes
Participants in this arm will be assigned to \~25% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
Unventilated Cigarettes
Participants in this arm will be assigned to \~0% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
|---|---|---|
|
Overall Study
STARTED
|
68
|
68
|
|
Overall Study
COMPLETED
|
44
|
38
|
|
Overall Study
NOT COMPLETED
|
24
|
30
|
Reasons for withdrawal
| Measure |
Ventilated Cigarettes
Participants in this arm will be assigned to \~25% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
Unventilated Cigarettes
Participants in this arm will be assigned to \~0% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
|---|---|---|
|
Overall Study
Lost to Follow-up
|
16
|
23
|
|
Overall Study
Withdrawal by Subject
|
4
|
3
|
|
Overall Study
Discontinued
|
4
|
4
|
Baseline Characteristics
COMET Study 1: Filter Ventilated Cigarette Substitution in the ETM
Baseline characteristics by cohort
| Measure |
Ventilated Cigarettes
n=44 Participants
Participants in this ARM will be assigned to \~25% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
Unventilated Cigarettes
n=38 Participants
Participants in this arm will be assigned to \~0% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
Total
n=82 Participants
Total of all reporting groups
|
|---|---|---|---|
|
Age, Continuous
|
45.61 Years of age
STANDARD_DEVIATION 11.21 • n=99 Participants
|
43.16 Years of age
STANDARD_DEVIATION 10.66 • n=107 Participants
|
44.48 Years of age
STANDARD_DEVIATION 10.96 • n=206 Participants
|
|
Sex: Female, Male
Female
|
22 Participants
n=99 Participants
|
24 Participants
n=107 Participants
|
46 Participants
n=206 Participants
|
|
Sex: Female, Male
Male
|
22 Participants
n=99 Participants
|
14 Participants
n=107 Participants
|
36 Participants
n=206 Participants
|
|
Ethnicity (NIH/OMB)
Hispanic or Latino
|
2 Participants
n=99 Participants
|
0 Participants
n=107 Participants
|
2 Participants
n=206 Participants
|
|
Ethnicity (NIH/OMB)
Not Hispanic or Latino
|
42 Participants
n=99 Participants
|
38 Participants
n=107 Participants
|
80 Participants
n=206 Participants
|
|
Ethnicity (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=99 Participants
|
0 Participants
n=107 Participants
|
0 Participants
n=206 Participants
|
|
Race (NIH/OMB)
American Indian or Alaska Native
|
2 Participants
n=99 Participants
|
0 Participants
n=107 Participants
|
2 Participants
n=206 Participants
|
|
Race (NIH/OMB)
Asian
|
0 Participants
n=99 Participants
|
0 Participants
n=107 Participants
|
0 Participants
n=206 Participants
|
|
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
|
0 Participants
n=99 Participants
|
0 Participants
n=107 Participants
|
0 Participants
n=206 Participants
|
|
Race (NIH/OMB)
Black or African American
|
6 Participants
n=99 Participants
|
4 Participants
n=107 Participants
|
10 Participants
n=206 Participants
|
|
Race (NIH/OMB)
White
|
35 Participants
n=99 Participants
|
33 Participants
n=107 Participants
|
68 Participants
n=206 Participants
|
|
Race (NIH/OMB)
More than one race
|
1 Participants
n=99 Participants
|
1 Participants
n=107 Participants
|
2 Participants
n=206 Participants
|
|
Race (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=99 Participants
|
0 Participants
n=107 Participants
|
0 Participants
n=206 Participants
|
|
Region of Enrollment
United States
|
44 participants
n=99 Participants
|
38 participants
n=107 Participants
|
82 participants
n=206 Participants
|
|
Cigarettes per day
|
19.91 Number of cigarettes
STANDARD_DEVIATION 6.28 • n=99 Participants
|
20.71 Number of cigarettes
STANDARD_DEVIATION 7.38 • n=107 Participants
|
20.28 Number of cigarettes
STANDARD_DEVIATION 6.78 • n=206 Participants
|
|
PHR High Ventilated Cigarettes
|
62.61 Scores on a scale
STANDARD_DEVIATION 22.44 • n=99 Participants
|
49.00 Scores on a scale
STANDARD_DEVIATION 21.14 • n=107 Participants
|
56.30 Scores on a scale
STANDARD_DEVIATION 22.76 • n=206 Participants
|
|
PHR Low Ventilated Cigarettes
|
62.61 Scores on a scale
STANDARD_DEVIATION 22.99 • n=99 Participants
|
49.76 Scores on a scale
STANDARD_DEVIATION 23.59 • n=107 Participants
|
56.66 Scores on a scale
STANDARD_DEVIATION 24.01 • n=206 Participants
|
|
Fagerstrom Test for Cigarette Dependence
|
3.93 Scores on a scale
STANDARD_DEVIATION 1.39 • n=99 Participants
|
4.16 Scores on a scale
STANDARD_DEVIATION 1.42 • n=107 Participants
|
4.04 Scores on a scale
STANDARD_DEVIATION 1.40 • n=206 Participants
|
|
QSU
|
43.98 Scores on a scale
STANDARD_DEVIATION 15.40 • n=99 Participants
|
44.03 Scores on a scale
STANDARD_DEVIATION 14.10 • n=107 Participants
|
44.00 Scores on a scale
STANDARD_DEVIATION 14.72 • n=206 Participants
|
|
RHQ
|
14.41 Scores on a scale
STANDARD_DEVIATION 7.08 • n=99 Participants
|
12.05 Scores on a scale
STANDARD_DEVIATION 5.36 • n=107 Participants
|
13.32 Scores on a scale
STANDARD_DEVIATION 6.42 • n=206 Participants
|
|
WISDM
|
182.48 Scores on a scale
STANDARD_DEVIATION 51.95 • n=99 Participants
|
180.53 Scores on a scale
STANDARD_DEVIATION 38.84 • n=107 Participants
|
181.57 Scores on a scale
STANDARD_DEVIATION 46.07 • n=206 Participants
|
|
MNWS
|
15.25 Scores on a scale
STANDARD_DEVIATION 10.65 • n=99 Participants
|
13.34 Scores on a scale
STANDARD_DEVIATION 8.87 • n=107 Participants
|
14.37 Scores on a scale
STANDARD_DEVIATION 9.85 • n=206 Participants
|
PRIMARY outcome
Timeframe: Week 2 (Session 1), Week 6 (Sessions 2), Week 10 (Session 3)Population: There are a few data points missing for a couple of participants; therefore, the sample size may be slightly different.
Participants completed purchasing trials in an experimental marketplace, a virtual store designed to mimic real-world shopping environments. In each lab session, participants completed multiple trials in which the price of their assigned cigarette increased progressively from $0.13 in the first trial to $4.00 in the final trial, while prices for other products (e-cigarettes, e-liquid, nicotine gum, snus, lozenges, and dip) remained constant. The mean and standard deviation of quantity purchased in each trial were calculated for all prices and sessions 1, 2, and 3.
Outcome measures
| Measure |
Ventilated Cigarettes
n=44 Participants
Participants in this ARM will be assigned to \~25% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
Unventilated Cigarettes
n=38 Participants
Participants in this arm will be assigned to \~0% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
|---|---|---|
|
High Ventilated Cigarette Purchases
S1: Price $0.13
|
104.22 single unit quantity purchased
Standard Deviation 89.69
|
29.64 single unit quantity purchased
Standard Deviation 42.16
|
|
High Ventilated Cigarette Purchases
S1: Price $0.25
|
52.38 single unit quantity purchased
Standard Deviation 53.34
|
47.41 single unit quantity purchased
Standard Deviation 47.85
|
|
High Ventilated Cigarette Purchases
S1: Price $0.50
|
22.22 single unit quantity purchased
Standard Deviation 26.45
|
61.77 single unit quantity purchased
Standard Deviation 54.45
|
|
High Ventilated Cigarette Purchases
S1: Price $1.00
|
10.68 single unit quantity purchased
Standard Deviation 14.35
|
68.58 single unit quantity purchased
Standard Deviation 58.21
|
|
High Ventilated Cigarette Purchases
S1: Price $2.00
|
4.97 single unit quantity purchased
Standard Deviation 7.08
|
78.83 single unit quantity purchased
Standard Deviation 65.29
|
|
High Ventilated Cigarette Purchases
S1: Price $4.00
|
1.75 single unit quantity purchased
Standard Deviation 2.90
|
79.02 single unit quantity purchased
Standard Deviation 64.63
|
|
High Ventilated Cigarette Purchases
S2: Price $0.13
|
104.55 single unit quantity purchased
Standard Deviation 70.02
|
28.32 single unit quantity purchased
Standard Deviation 54.07
|
|
High Ventilated Cigarette Purchases
S2: Price $0.25
|
54.65 single unit quantity purchased
Standard Deviation 56.45
|
39.37 single unit quantity purchased
Standard Deviation 60.72
|
|
High Ventilated Cigarette Purchases
S2: Price $0.50
|
15.61 single unit quantity purchased
Standard Deviation 25.92
|
89.70 single unit quantity purchased
Standard Deviation 74.59
|
|
High Ventilated Cigarette Purchases
S2: Price $1.00
|
4.52 single unit quantity purchased
Standard Deviation 9.06
|
94.11 single unit quantity purchased
Standard Deviation 73.46
|
|
High Ventilated Cigarette Purchases
S2: Price $2.00
|
2.18 single unit quantity purchased
Standard Deviation 4.61
|
97.91 single unit quantity purchased
Standard Deviation 70.87
|
|
High Ventilated Cigarette Purchases
S2: Price $4.00
|
1.03 single unit quantity purchased
Standard Deviation 2.60
|
98.73 single unit quantity purchased
Standard Deviation 70.93
|
|
High Ventilated Cigarette Purchases
S3: Price $0.13
|
102.18 single unit quantity purchased
Standard Deviation 90.28
|
21.36 single unit quantity purchased
Standard Deviation 53.31
|
|
High Ventilated Cigarette Purchases
S3: Price $0.25
|
59.59 single unit quantity purchased
Standard Deviation 57.12
|
38.84 single unit quantity purchased
Standard Deviation 62.49
|
|
High Ventilated Cigarette Purchases
S3: Price $0.50
|
14.79 single unit quantity purchased
Standard Deviation 22.88
|
80.79 single unit quantity purchased
Standard Deviation 72.76
|
|
High Ventilated Cigarette Purchases
S3: Price $1.00
|
5.38 single unit quantity purchased
Standard Deviation 9.75
|
83.03 single unit quantity purchased
Standard Deviation 70.57
|
|
High Ventilated Cigarette Purchases
S3: Price $2.00
|
2.95 single unit quantity purchased
Standard Deviation 5.91
|
93.66 single unit quantity purchased
Standard Deviation 73.98
|
|
High Ventilated Cigarette Purchases
S3: Price $4.00
|
1.50 single unit quantity purchased
Standard Deviation 2.88
|
87.03 single unit quantity purchased
Standard Deviation 67.09
|
PRIMARY outcome
Timeframe: Week 2 (Session 1), Week 6 (Sessions 2), Week 10 (Session 3)Population: There are a few data points missing for a couple of participants; therefore, the sample size may be slightly different.
Participants completed purchasing trials in an experimental marketplace, a virtual store designed to mimic real-world shopping environments. In each lab session, participants completed multiple trials in which the price of High Ventilated Cigarettes (HVC) increased progressively from $0.13 in the first trial to $4.00 in the final trial foe ventilated cigarette users and Low Ventilated Cigarettes (LVC) increased progressively from $0.13 in the first trial to $4.00 for the unventilated group, while prices for other products (Low Ventilated Cigarettes (LVC), e-cigarettes, e-liquid, nicotine gum, snus, lozenges, and dip) remained constant. The mean and standard deviation of quantity purchased in each trial was calculated for all prices and sessions 1, 2, and 3.
Outcome measures
| Measure |
Ventilated Cigarettes
n=44 Participants
Participants in this ARM will be assigned to \~25% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
Unventilated Cigarettes
n=38 Participants
Participants in this arm will be assigned to \~0% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
|---|---|---|
|
Low Ventilated Cigarette Purchases
S1: Price $0.13
|
40.84 single unit quantity purchased
Standard Deviation 58.73
|
123.91 single unit quantity purchased
Standard Deviation 96.10
|
|
Low Ventilated Cigarette Purchases
S1: Price $0.25
|
53.52 single unit quantity purchased
Standard Deviation 64.66
|
70.39 single unit quantity purchased
Standard Deviation 64.85
|
|
Low Ventilated Cigarette Purchases
S1: Price $0.50
|
56.29 single unit quantity purchased
Standard Deviation 62.22
|
28.89 single unit quantity purchased
Standard Deviation 34.04
|
|
Low Ventilated Cigarette Purchases
S1: Price $1.00
|
56.86 single unit quantity purchased
Standard Deviation 66.67
|
9.36 single unit quantity purchased
Standard Deviation 17.44
|
|
Low Ventilated Cigarette Purchases
S1: Price $2.00
|
58.45 single unit quantity purchased
Standard Deviation 63.78
|
3.33 single unit quantity purchased
Standard Deviation 7.38
|
|
Low Ventilated Cigarette Purchases
S1: Price $4.00
|
62.91 single unit quantity purchased
Standard Deviation 61.87
|
0.97 single unit quantity purchased
Standard Deviation 3.28
|
|
Low Ventilated Cigarette Purchases
S2: Price $0.13
|
25.27 single unit quantity purchased
Standard Deviation 44.72
|
127.92 single unit quantity purchased
Standard Deviation 106.05
|
|
Low Ventilated Cigarette Purchases
S2: Price $0.25
|
46.16 single unit quantity purchased
Standard Deviation 56.88
|
77.08 single unit quantity purchased
Standard Deviation 74.06
|
|
Low Ventilated Cigarette Purchases
S2: Price $0.50
|
70.81 single unit quantity purchased
Standard Deviation 62.72
|
13.86 single unit quantity purchased
Standard Deviation 25.67
|
|
Low Ventilated Cigarette Purchases
S2: Price $1.00
|
77.59 single unit quantity purchased
Standard Deviation 61.05
|
5.21 single unit quantity purchased
Standard Deviation 13.95
|
|
Low Ventilated Cigarette Purchases
S2: Price $2.00
|
77.25 single unit quantity purchased
Standard Deviation 60.82
|
1.73 single unit quantity purchased
Standard Deviation 5.79
|
|
Low Ventilated Cigarette Purchases
S2: Price $4.00
|
82.09 single unit quantity purchased
Standard Deviation 61.17
|
0.76 single unit quantity purchased
Standard Deviation 2.73
|
|
Low Ventilated Cigarette Purchases
S3: Price $0.13
|
26.47 single unit quantity purchased
Standard Deviation 56.64
|
122.76 single unit quantity purchased
Standard Deviation 99.18
|
|
Low Ventilated Cigarette Purchases
S3: Price $0.25
|
38.63 single unit quantity purchased
Standard Deviation 58.61
|
60.65 single unit quantity purchased
Standard Deviation 71.91
|
|
Low Ventilated Cigarette Purchases
S3: Price $0.50
|
66.32 single unit quantity purchased
Standard Deviation 62.23
|
8.97 single unit quantity purchased
Standard Deviation 22.86
|
|
Low Ventilated Cigarette Purchases
S3: Price $1.00
|
69.02 single unit quantity purchased
Standard Deviation 61.75
|
1.94 single unit quantity purchased
Standard Deviation 7.12
|
|
Low Ventilated Cigarette Purchases
S3: Price $2.00
|
69.91 single unit quantity purchased
Standard Deviation 61.74
|
0.32 single unit quantity purchased
Standard Deviation 1.25
|
|
Low Ventilated Cigarette Purchases
S3: Price $4.00
|
71.64 single unit quantity purchased
Standard Deviation 60.94
|
0.11 single unit quantity purchased
Standard Deviation 0.51
|
PRIMARY outcome
Timeframe: Week 2 (Session 1), Week 6 (Sessions 2), Week 10 (Session 3)Population: There are a few data points missing for a couple of participants; therefore, the sample size may be slightly different.
Participants completed purchasing trials in an experimental marketplace, a virtual store designed to mimic real-world shopping environments. In each lab session, participants completed multiple trials in which the price of High Ventilated Cigarettes (HVC) increased progressively from $0.13 in the first trial to $4.00 in the final trial for ventilated cigarette users and Low Ventilated Cigarettes (LVC) increased progressively from $0.13 in the first trial to $4.00 for the unventilated group, while prices for other products (Low Ventilated Cigarettes (LVC), e-cigarettes, e-liquid, nicotine gum, snus, lozenges, and dip) remained constant. The mean and standard deviation of quantity purchased in each trial was calculated for all prices and sessions 1, 2, and 3.
Outcome measures
| Measure |
Ventilated Cigarettes
n=44 Participants
Participants in this ARM will be assigned to \~25% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
Unventilated Cigarettes
n=38 Participants
Participants in this arm will be assigned to \~0% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
|---|---|---|
|
E-Cigarette Purchases
S1: Price $0.13
|
0.32 single unit quantity purchased
Standard Deviation 0.70
|
0.47 single unit quantity purchased
Standard Deviation 0.73
|
|
E-Cigarette Purchases
S1: Price $0.25
|
0.32 single unit quantity purchased
Standard Deviation 0.67
|
0.44 single unit quantity purchased
Standard Deviation 0.69
|
|
E-Cigarette Purchases
S1: Price $0.50
|
0.27 single unit quantity purchased
Standard Deviation 0.65
|
0.52 single unit quantity purchased
Standard Deviation 0.77
|
|
E-Cigarette Purchases
S1: Price $1.00
|
0.50 single unit quantity purchased
Standard Deviation 1.13
|
0.86 single unit quantity purchased
Standard Deviation 2.05
|
|
E-Cigarette Purchases
S1: Price $2.00
|
0.50 single unit quantity purchased
Standard Deviation 1.02
|
0.91 single unit quantity purchased
Standard Deviation 2.40
|
|
E-Cigarette Purchases
S1: Price $4.00
|
0.72 single unit quantity purchased
Standard Deviation 1.32
|
1.16 single unit quantity purchased
Standard Deviation 2.51
|
|
E-Cigarette Purchases
S2: Price $0.13
|
0.15 single unit quantity purchased
Standard Deviation 0.56
|
0.27 single unit quantity purchased
Standard Deviation 0.56
|
|
E-Cigarette Purchases
S2: Price $0.25
|
0.09 single unit quantity purchased
Standard Deviation 0.47
|
0.22 single unit quantity purchased
Standard Deviation 0.42
|
|
E-Cigarette Purchases
S2: Price $0.50
|
0.11 single unit quantity purchased
Standard Deviation 0.49
|
0.27 single unit quantity purchased
Standard Deviation 0.45
|
|
E-Cigarette Purchases
S2: Price $1.00
|
0.18 single unit quantity purchased
Standard Deviation 0.65
|
0.29 single unit quantity purchased
Standard Deviation 0.57
|
|
E-Cigarette Purchases
S2: Price $2.00
|
0.13 single unit quantity purchased
Standard Deviation 0.63
|
0.29 single unit quantity purchased
Standard Deviation 0.61
|
|
E-Cigarette Purchases
S2: Price $4.00
|
0.13 single unit quantity purchased
Standard Deviation 0.63
|
0.29 single unit quantity purchased
Standard Deviation 0.61
|
|
E-Cigarette Purchases
S3: Price $0.13
|
0.14 single unit quantity purchased
Standard Deviation 0.51
|
0.08 single unit quantity purchased
Standard Deviation 0.27
|
|
E-Cigarette Purchases
S3: Price $0.25
|
0.09 single unit quantity purchased
Standard Deviation 0.47
|
0.16 single unit quantity purchased
Standard Deviation 0.44
|
|
E-Cigarette Purchases
S3: Price $0.50
|
0.11 single unit quantity purchased
Standard Deviation 0.62
|
0.24 single unit quantity purchased
Standard Deviation 0.43
|
|
E-Cigarette Purchases
S3: Price $1.00
|
0.13 single unit quantity purchased
Standard Deviation 0.63
|
0.29 single unit quantity purchased
Standard Deviation 0.61
|
|
E-Cigarette Purchases
S3: Price $2.00
|
0.13 single unit quantity purchased
Standard Deviation 0.63
|
0.29 single unit quantity purchased
Standard Deviation 0.52
|
|
E-Cigarette Purchases
S3: Price $4.00
|
0.13 single unit quantity purchased
Standard Deviation 0.63
|
0.32 single unit quantity purchased
Standard Deviation 0.57
|
PRIMARY outcome
Timeframe: Week 2 (Session 1), Week 6 (Sessions 2), Week 10 (Session 3)Population: There are a few data points missing for a couple of participants; therefore, the sample size may be slightly different.
Participants completed purchasing trials in an experimental marketplace, a virtual store designed to mimic real-world shopping environments. In each lab session, participants completed multiple trials in which the price of High Ventilated Cigarettes (HVC) increased progressively from $0.13 in the first trial to $4.00 in the final trial foe ventilated cigarette users and Low Ventilated Cigarettes (LVC) increased progressively from $0.13 in the first trial to $4.00 for the unventilated group, while prices for other products (Low Ventilated Cigarettes (LVC), e-cigarettes, e-liquid, nicotine gum, snus, lozenges, and dip) remained constant. The mean and standard deviation of quantity purchased in each trial was calculated for all prices and sessions 1, 2, and 3.
Outcome measures
| Measure |
Ventilated Cigarettes
n=44 Participants
Participants in this ARM will be assigned to \~25% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
Unventilated Cigarettes
n=38 Participants
Participants in this arm will be assigned to \~0% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
|---|---|---|
|
E-liquid Purchases
S1: Price $0.13
|
0.18 single unit quantity purchased
Standard Deviation 0.81
|
0.31 single unit quantity purchased
Standard Deviation 1.19
|
|
E-liquid Purchases
S1: Price $0.25
|
0.09 single unit quantity purchased
Standard Deviation 0.36
|
0.08 single unit quantity purchased
Standard Deviation 0.50
|
|
E-liquid Purchases
S1: Price $0.50
|
0.05 single unit quantity purchased
Standard Deviation 0.21
|
0.13 single unit quantity purchased
Standard Deviation 0.83
|
|
E-liquid Purchases
S1: Price $1.00
|
0.09 single unit quantity purchased
Standard Deviation 0.36
|
0.19 single unit quantity purchased
Standard Deviation 1.16
|
|
E-liquid Purchases
S1: Price $2.00
|
0.05 single unit quantity purchased
Standard Deviation 0.21
|
0.25 single unit quantity purchased
Standard Deviation 1.50
|
|
E-liquid Purchases
S1: Price $4.00
|
0.09 single unit quantity purchased
Standard Deviation 0.36
|
0.22 single unit quantity purchased
Standard Deviation 1.17
|
|
E-liquid Purchases
S2: Price $0.13
|
0.07 single unit quantity purchased
Standard Deviation 0.45
|
0.08 single unit quantity purchased
Standard Deviation 0.36
|
|
E-liquid Purchases
S2: Price $0.25
|
0.07 single unit quantity purchased
Standard Deviation 0.45
|
0.08 single unit quantity purchased
Standard Deviation 0.36
|
|
E-liquid Purchases
S2: Price $0.50
|
0.07 single unit quantity purchased
Standard Deviation 0.45
|
0.08 single unit quantity purchased
Standard Deviation 0.36
|
|
E-liquid Purchases
S2: Price $1.00
|
0.18 single unit quantity purchased
Standard Deviation 0.87
|
0.08 single unit quantity purchased
Standard Deviation 0.36
|
|
E-liquid Purchases
S2: Price $2.00
|
0.07 single unit quantity purchased
Standard Deviation 0.45
|
0.13 single unit quantity purchased
Standard Deviation 0.48
|
|
E-liquid Purchases
S2: Price $4.00
|
0.07 single unit quantity purchased
Standard Deviation 0.45
|
0.11 single unit quantity purchased
Standard Deviation 0.45
|
|
E-liquid Purchases
S3: Price $0.13
|
0.07 single unit quantity purchased
Standard Deviation 0.45
|
0.21 single unit quantity purchased
Standard Deviation 0.74
|
|
E-liquid Purchases
S3: Price $0.25
|
0.09 single unit quantity purchased
Standard Deviation 0.60
|
0.15 single unit quantity purchased
Standard Deviation 0.49
|
|
E-liquid Purchases
S3: Price $0.50
|
0.14 single unit quantity purchased
Standard Deviation 0.90
|
0.10 single unit quantity purchased
Standard Deviation 0.38
|
|
E-liquid Purchases
S3: Price $1.00
|
0.18 single unit quantity purchased
Standard Deviation 1.21
|
0.10 single unit quantity purchased
Standard Deviation 0.38
|
|
E-liquid Purchases
S3: Price $2.00
|
0.16 single unit quantity purchased
Standard Deviation 1.05
|
0.10 single unit quantity purchased
Standard Deviation 0.38
|
|
E-liquid Purchases
S3: Price $4.00
|
0.14 single unit quantity purchased
Standard Deviation 0.90
|
0.10 single unit quantity purchased
Standard Deviation 0.38
|
PRIMARY outcome
Timeframe: Week 2 (Session 1), Week 6 (Sessions 2), Week 10 (Session 3)Population: There are a few data points missing for a couple of participants; therefore, the sample size may be slightly different.
Participants completed purchasing trials in an experimental marketplace, a virtual store designed to mimic real-world shopping environments. In each lab session, participants completed multiple trials in which the price of High Ventilated Cigarettes (HVC) increased progressively from $0.13 in the first trial to $4.00 in the final trial foe ventilated cigarette users and Low Ventilated Cigarettes (LVC) increased progressively from $0.13 in the first trial to $4.00 for the unventilated group, while prices for other products (Low Ventilated Cigarettes (LVC), e-cigarettes, e-liquid, nicotine gum, snus, lozenges, and dip) remained constant. The mean and standard deviation of quantity purchased in each trial was calculated for all prices and sessions 1, 2, and 3.
Outcome measures
| Measure |
Ventilated Cigarettes
n=44 Participants
Participants in this ARM will be assigned to \~25% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
Unventilated Cigarettes
n=38 Participants
Participants in this arm will be assigned to \~0% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
|---|---|---|
|
Gum Purchases
S1: Price $0.13
|
0.27 single unit quantity purchased
Standard Deviation 0.89
|
0.39 single unit quantity purchased
Standard Deviation 1.17
|
|
Gum Purchases
S1: Price $0.25
|
0.29 single unit quantity purchased
Standard Deviation 0.90
|
0.17 single unit quantity purchased
Standard Deviation 0.61
|
|
Gum Purchases
S1: Price $0.50
|
0.25 single unit quantity purchased
Standard Deviation 0.97
|
0.25 single unit quantity purchased
Standard Deviation 1.05
|
|
Gum Purchases
S1: Price $1.00
|
0.14 single unit quantity purchased
Standard Deviation 0.41
|
0.39 single unit quantity purchased
Standard Deviation 1.27
|
|
Gum Purchases
S1: Price $2.00
|
0.11 single unit quantity purchased
Standard Deviation 0.39
|
0.39 single unit quantity purchased
Standard Deviation 1.36
|
|
Gum Purchases
S1: Price $4.00
|
0.34 single unit quantity purchased
Standard Deviation 1.23
|
0.31 single unit quantity purchased
Standard Deviation 1.19
|
|
Gum Purchases
S2: Price $0.13
|
0.09 single unit quantity purchased
Standard Deviation 0.60
|
0.08 single unit quantity purchased
Standard Deviation 0.36
|
|
Gum Purchases
S2: Price $0.25
|
0.09 single unit quantity purchased
Standard Deviation 0.60
|
0.03 single unit quantity purchased
Standard Deviation 0.16
|
|
Gum Purchases
S2: Price $0.50
|
0.09 single unit quantity purchased
Standard Deviation 0.60
|
0.0 single unit quantity purchased
Standard Deviation 0.0
|
|
Gum Purchases
S2: Price $1.00
|
0.09 single unit quantity purchased
Standard Deviation 0.60
|
0.37 single unit quantity purchased
Standard Deviation 1.53
|
|
Gum Purchases
S2: Price $2.00
|
0.09 single unit quantity purchased
Standard Deviation 0.60
|
0.05 single unit quantity purchased
Standard Deviation 0.33
|
|
Gum Purchases
S2: Price $4.00
|
0.09 single unit quantity purchased
Standard Deviation 0.60
|
0.73 single unit quantity purchased
Standard Deviation 3.45
|
|
Gum Purchases
S3: Price $0.13
|
0.05 single unit quantity purchased
Standard Deviation 0.30
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Gum Purchases
S3: Price $0.25
|
0.05 single unit quantity purchased
Standard Deviation 0.30
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Gum Purchases
S3: Price $0.50
|
0.05 single unit quantity purchased
Standard Deviation 0.30
|
0.26 single unit quantity purchased
Standard Deviation 1.62
|
|
Gum Purchases
S3: Price $1.00
|
0.05 single unit quantity purchased
Standard Deviation 0.30
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Gum Purchases
S3: Price $2.00
|
0.05 single unit quantity purchased
Standard Deviation 0.30
|
0.05 single unit quantity purchased
Standard Deviation 0.32
|
|
Gum Purchases
S3: Price $4.00
|
0.05 single unit quantity purchased
Standard Deviation 0.30
|
0.32 single unit quantity purchased
Standard Deviation 1.64
|
PRIMARY outcome
Timeframe: Week 2 (Session 1), Week 6 (Sessions 2), Week 10 (Session 3)Population: There are a few data points missing for a couple of participants; therefore, the sample size may be slightly different.
Participants completed purchasing trials in an experimental marketplace, a virtual store designed to mimic real-world shopping environments. In each lab session, participants completed multiple trials in which the price of High Ventilated Cigarettes (HVC) increased progressively from $0.13 in the first trial to $4.00 in the final trial foe ventilated cigarette users and Low Ventilated Cigarettes (LVC) increased progressively from $0.13 in the first trial to $4.00 for the unventilated group, while prices for other products (Low Ventilated Cigarettes (LVC), e-cigarettes, e-liquid, nicotine gum, snus, lozenges, and dip) remained constant. The mean and standard deviation of quantity purchased in each trial was calculated for all prices and sessions 1, 2, and 3.
Outcome measures
| Measure |
Ventilated Cigarettes
n=44 Participants
Participants in this ARM will be assigned to \~25% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
Unventilated Cigarettes
n=38 Participants
Participants in this arm will be assigned to \~0% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
|---|---|---|
|
Snus Purchases
S1: Price $0.13
|
0.27 single unit quantity purchased
Standard Deviation 1.81
|
0.33 single unit quantity purchased
Standard Deviation 2.00
|
|
Snus Purchases
S1: Price $0.25
|
0.05 single unit quantity purchased
Standard Deviation 0.30
|
0.28 single unit quantity purchased
Standard Deviation 1.67
|
|
Snus Purchases
S1: Price $0.50
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Snus Purchases
S1: Price $1.00
|
0.05 single unit quantity purchased
Standard Deviation 0.30
|
0.11 single unit quantity purchased
Standard Deviation 0.67
|
|
Snus Purchases
S1: Price $2.00
|
0.05 single unit quantity purchased
Standard Deviation 0.30
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Snus Purchases
S1: Price $4.00
|
0.23 single unit quantity purchased
Standard Deviation 0.15
|
0.17 single unit quantity purchased
Standard Deviation 1.00
|
|
Snus Purchases
S2: Price $0.13
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Snus Purchases
S2: Price $0.25
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Snus Purchases
S2: Price $0.50
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Snus Purchases
S2: Price $1.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Snus Purchases
S2: Price $2.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Snus Purchases
S2: Price $4.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.27 single unit quantity purchased
Standard Deviation 1.64
|
|
Snus Purchases
S3: Price $0.13
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
1.31 single unit quantity purchased
Standard Deviation 8.11
|
|
Snus Purchases
S3: Price $0.25
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Snus Purchases
S3: Price $0.50
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Snus Purchases
S3: Price $1.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
1.31 single unit quantity purchased
Standard Deviation 8.11
|
|
Snus Purchases
S3: Price $2.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Snus Purchases
S3: Price $4.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
1.36 single unit quantity purchased
Standard Deviation 8.12
|
PRIMARY outcome
Timeframe: Week 2 (Session 1), Week 6 (Sessions 2), Week 10 (Session 3)Population: There are a few data points missing for a couple of participants; therefore, the sample size may be slightly different.
Participants completed purchasing trials in an experimental marketplace, a virtual store designed to mimic real-world shopping environments. In each lab session, participants completed multiple trials in which the price of High Ventilated Cigarettes (HVC) increased progressively from $0.13 in the first trial to $4.00 in the final trial foe ventilated cigarette users and Low Ventilated Cigarettes (LVC) increased progressively from $0.13 in the first trial to $4.00 for the unventilated group, while prices for other products (Low Ventilated Cigarettes (LVC), e-cigarettes, e-liquid, nicotine gum, snus, lozenges, and dip) remained constant. The mean and standard deviation of quantity purchased in each trial was calculated for all prices and sessions 1, 2, and 3.
Outcome measures
| Measure |
Ventilated Cigarettes
n=44 Participants
Participants in this ARM will be assigned to \~25% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
Unventilated Cigarettes
n=38 Participants
Participants in this arm will be assigned to \~0% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
|---|---|---|
|
Lozenge Purchases
S1: Price $0.13
|
0.91 single unit quantity purchased
Standard Deviation 4.34
|
0.31 single unit quantity purchased
Standard Deviation 1.32
|
|
Lozenge Purchases
S1: Price $0.25
|
0.45 single unit quantity purchased
Standard Deviation 3.02
|
0.22 single unit quantity purchased
Standard Deviation 0.93
|
|
Lozenge Purchases
S1: Price $0.50
|
1.25 single unit quantity purchased
Standard Deviation 6.01
|
0.11 single unit quantity purchased
Standard Deviation 0.67
|
|
Lozenge Purchases
S1: Price $1.00
|
0.45 single unit quantity purchased
Standard Deviation 3.02
|
0.19 single unit quantity purchased
Standard Deviation 0.82
|
|
Lozenge Purchases
S1: Price $2.00
|
0.47 single unit quantity purchased
Standard Deviation 3.02
|
0.28 single unit quantity purchased
Standard Deviation 1.19
|
|
Lozenge Purchases
S1: Price $4.00
|
0.45 single unit quantity purchased
Standard Deviation 3.02
|
0.22 single unit quantity purchased
Standard Deviation 0.93
|
|
Lozenge Purchases
S2: Price $0.13
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Lozenge Purchases
S2: Price $0.25
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Lozenge Purchases
S2: Price $0.50
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Lozenge Purchases
S2: Price $1.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Lozenge Purchases
S2: Price $2.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Lozenge Purchases
S2: Price $4.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Lozenge Purchases
S3: Price $0.13
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Lozenge Purchases
S3: Price $0.25
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Lozenge Purchases
S3: Price $0.50
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Lozenge Purchases
S3: Price $1.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Lozenge Purchases
S3: Price $2.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Lozenge Purchases
S3: Price $4.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
PRIMARY outcome
Timeframe: Week 2 (Session 1), Week 6 (Sessions 2), Week 10 (Session 3)Population: There are a few data points missing for a couple of participants; therefore, the sample size may be slightly different.
Participants completed purchasing trials in an experimental marketplace, a virtual store designed to mimic real-world shopping environments. In each lab session, participants completed multiple trials in which the price of High Ventilated Cigarettes (HVC) increased progressively from $0.13 in the first trial to $4.00 in the final trial foe ventilated cigarette users and Low Ventilated Cigarettes (LVC) increased progressively from $0.13 in the first trial to $4.00 for the unventilated group, while prices for other products (Low Ventilated Cigarettes (LVC), e-cigarettes, e-liquid, nicotine gum, snus, lozenges, and dip) remained constant. The mean and standard deviation of quantity purchased in each trial was calculated for all prices and sessions 1, 2, and 3.
Outcome measures
| Measure |
Ventilated Cigarettes
n=44 Participants
Participants in this ARM will be assigned to \~25% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
Unventilated Cigarettes
n=38 Participants
Participants in this arm will be assigned to \~0% filter ventilation commercially available cigarettes.
Commercially available cigarette: Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.
|
|---|---|---|
|
Dip Purchases
S1: Price $0.13
|
0.07 single unit quantity purchased
Standard Deviation 0.45
|
0.17 single unit quantity purchased
Standard Deviation 1.00
|
|
Dip Purchases
S1: Price $0.25
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Dip Purchases
S1: Price $0.50
|
0.14 single unit quantity purchased
Standard Deviation 0.90
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Dip Purchases
S1: Price $1.00
|
0.07 single unit quantity purchased
Standard Deviation 0.33
|
0.06 single unit quantity purchased
Standard Deviation 0.33
|
|
Dip Purchases
S1: Price $2.00
|
0.05 single unit quantity purchased
Standard Deviation 0.30
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Dip Purchases
S1: Price $4.00
|
0.09 single unit quantity purchased
Standard Deviation 0.60
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
|
Dip Purchases
S2: Price $0.13
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.32 single unit quantity purchased
Standard Deviation 1.97
|
|
Dip Purchases
S2: Price $0.25
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.22 single unit quantity purchased
Standard Deviation 1.32
|
|
Dip Purchases
S2: Price $0.50
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.27 single unit quantity purchased
Standard Deviation 1.64
|
|
Dip Purchases
S2: Price $1.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.05 single unit quantity purchased
Standard Deviation 0.33
|
|
Dip Purchases
S2: Price $2.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.27 single unit quantity purchased
Standard Deviation 1.64
|
|
Dip Purchases
S2: Price $4.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.49 single unit quantity purchased
Standard Deviation 2.37
|
|
Dip Purchases
S3: Price $0.13
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.39 single unit quantity purchased
Standard Deviation 2.43
|
|
Dip Purchases
S3: Price $0.25
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.55 single unit quantity purchased
Standard Deviation 3.41
|
|
Dip Purchases
S3: Price $0.50
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.55 single unit quantity purchased
Standard Deviation 3.41
|
|
Dip Purchases
S3: Price $1.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.61 single unit quantity purchased
Standard Deviation 3.73
|
|
Dip Purchases
S3: Price $2.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.66 single unit quantity purchased
Standard Deviation 4.06
|
|
Dip Purchases
S3: Price $4.00
|
0.00 single unit quantity purchased
Standard Deviation 0.00
|
0.68 single unit quantity purchased
Standard Deviation 4.06
|
Adverse Events
Ventilated Cigarettes
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Unventilated Cigarettes
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Dr. Roberta Freitas-Lemos
Fralin Biomedical Research Institute at VTC
Phone: 540 526 2106
Email: [email protected]
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place