Clinical Trials Updated in 2025

NCT04600414 | COMPLETED | NA

254 participants

Collaborating to Heal Addiction and Mental Health in Primary Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2020-11-16
Completion:: 2024-02-15

Conditions

Opioid-use Disorder
Mental Health Disorder

Interventions

OTHER

Results Available

NCT04519645 | TERMINATED | PHASE2

29 participants

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Lacosamide in Neonates With Repeated Electroencephalographic Neonatal Seizures

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2021-03-31
Completion:: 2024-08-06

Conditions

Electroencephalographic Neonatal Seizures
Epilepsy

Interventions

DRUG
OTHER

Results Available

NCT04488198 | ACTIVE_NOT_RECRUITING | NA

60 participants

Acupuncture in Pediatrics and Adolescents With Chronic Inflammatory Bowel Diseases

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2019-03-01
Completion:: 2026-12-31

Conditions

Morbus Crohn
Colitis, Ulcerative

Interventions

OTHER

No Results Yet

NCT04458909 | TERMINATED | PHASE3

15 participants

Testing the Addition of an Anti-cancer Immune Therapy Drug (Nivolumab) to the Usual Chemotherapy Treatment (Cisplatin or Carboplatin With Gemcitabine) for Recurrent or Metastatic Nasopharyngeal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2020-12-09
Completion:: 2023-08-15

Conditions

Metastatic Nasopharyngeal Carcinoma
Metastatic Nasopharyngeal Keratinizing Squamous Cell Carcinoma
Metastatic Nasopharyngeal Nonkeratinizing Carcinoma
Metastatic Nasopharyngeal Undifferentiated Carcinoma
Nasopharyngeal Nonkeratinizing Carcinoma
Recurrent Nasopharyngeal Carcinoma
Recurrent Nasopharyngeal Keratinizing Squamous Cell Carcinoma
Recurrent Nasopharyngeal Undifferentiated Carcinoma
Stage IV Nasopharyngeal Carcinoma AJCC v8
Stage IVA Nasopharyngeal Carcinoma AJCC v8
Stage IVB Nasopharyngeal Carcinoma AJCC v8

Interventions

DRUG
BIOLOGICAL
OTHER

Results Available

NCT04447755 | COMPLETED | PHASE2

127 participants

A Study of Lenvatinib (MK-7902) in Pediatric Participants With Relapsed or Refractory Solid Malignancies (MK-7902-013/E7080)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2020-07-30
Completion:: 2022-09-16

Conditions

Relapsed or Refractory Solid Tumors

Interventions

DRUG

Results Available

NCT04393103 | WITHDRAWN | PHASE2/PHASE3

0 participants

Role of Intralipid in Management of Organophosphorus Poisoning

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2024-04-01
Completion:: 2025-01-01

Conditions

Organophosphorus Poisoning

Interventions

DRUG

No Results Yet

NCT04392284 | COMPLETED | NA

40 participants

Developing an Adaptive Lifestyle Intervention Program in Family Medicine Clinics

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2021-04-19
Completion:: 2022-06-03

Conditions

Insulin Resistance
Obesity
Diabetes
Hypertension
Dyslipidemias
Metabolic Syndrome

Interventions

BEHAVIORAL

No Results Yet

NCT04371081 | ACTIVE_NOT_RECRUITING

70 participants

Amplatzer Piccolo Occluder Japan Post-marketing Database Surveillance

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-03
Start Date:: 2020-04-01
Completion:: 2025-09-10

Conditions

Patent Ductus Arteriosus

Interventions

DEVICE

No Results Yet

NCT04342026 | RECRUITING

1452 participants

Role of the Environment and Endocrine Disruptors in Child Cryptorchidism

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-03
Start Date:: 2020-04-16
Completion:: 2027-10-15

Conditions

Cryptorchidism

Interventions

OTHER

No Results Yet

NCT04296903 | ACTIVE_NOT_RECRUITING | NA

201 participants

Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2020-05-31
Completion:: 2029-06-30

Conditions

Adolescent Idiopathic Scoliosis

Interventions

DEVICE

No Results Yet

NCT04287192 | RECRUITING | NA

640 participants

Digital Bridge: Using Technology to Support Patient-centered Care Transitions From Hospital to Home

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2023-04-15
Completion:: 2026-03-30

Conditions

Older Adults With Complex Care Needs

Interventions

OTHER

No Results Yet

NCT04268849 | RECRUITING | PHASE3

104 participants

Trial of IV vs Oral Iron Treatment of Iron Deficiency Anemia in the Post-Operative Bariatric Surgical Patient

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2020-02-27
Completion:: 2025-11-30

Conditions

Iron Deficiency Anemia

Interventions

DRUG

No Results Yet

NCT04243447 | ACTIVE_NOT_RECRUITING

747 participants

Identification of Predictors for Clinical Outcomes in Femoroacetabular Impingement Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-03
Start Date:: 2020-02-02
Completion:: 2025-11-29

Conditions

Femoracetabular Impingement

No Results Yet

NCT04215978 | COMPLETED | PHASE1

204 participants

Safety and Preliminary Effectiveness of BGB-A445 in Combination With Tislelizumab in Participants With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2020-01-30
Completion:: 2025-01-24

Conditions

Advanced Solid Tumor
Non Small Cell Lung Cancer
Head and Neck Squamous Cell Carcinoma (HNSCC)
Nasopharyngeal Carcinoma (NPC)

Interventions

DRUG

No Results Yet

NCT04202354 | COMPLETED | PHASE1/PHASE2

50 participants

Study of ARO-HSD in Healthy Volunteers and Patients With Non-Alcoholic Steatohepatitis (NASH) or Suspected NASH

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2020-03-03
Completion:: 2021-09-03

Conditions

Non-alcoholic Steatohepatitis

Interventions

DRUG

Results Available

NCT04201067 | COMPLETED

240 participants

Large-Scale Metabolomic Profiling for the Diagnosis of Inborn Errors of Metabolism

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-03
Start Date:: 2019-10-08
Completion:: 2025-03-12

Conditions

Congenital Disorders of Glycosylation

No Results Yet

NCT04171440 | COMPLETED | NA

91 participants

Observation of Perioperative Outcomes of Robotic Pancreaticoduodenectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2020-02-18
Completion:: 2024-12-31

Conditions

Pancreaticoduodenectomy

Interventions

PROCEDURE

No Results Yet

NCT04166513 | COMPLETED | NA

25 participants

Effects of Transcranial Direct Current Stimulation (tDCS) on Language

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2019-12-13
Completion:: 2024-07-01

Conditions

Stroke
Aphasia

Interventions

DEVICE
BEHAVIORAL

Results Available

NCT04124406 | ACTIVE_NOT_RECRUITING

150000 participants

Voyage: Real-World Impact of the Multi-target Stool DNA Test on CRC Screening and Mortality

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-03
Start Date:: 2019-10-18
Completion:: 2023-12-31

Conditions

Colon Cancer

Interventions

DEVICE

No Results Yet

NCT04108026 | COMPLETED | PHASE2

50 participants

Immunotherapy in Patient With Poor General Condition

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2020-10-14
Completion:: 2023-11-30

Conditions

Non-small Cell Lung Cancer Stage IV

Interventions

DRUG

No Results Yet

NCT04095676 | RECRUITING | NA

184 participants

VATS Surgery Compared to Drainage in the Treatment of Pleural Empyema

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2022-10-30
Completion:: 2027-10-30

Conditions

Pleural Empyema

Interventions

PROCEDURE

No Results Yet

NCT04068480 | RECRUITING

300 participants

Esophageal and Gastric Diseases With Robotically Controlled Magnetic Capsule Endoscopy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-03
Start Date:: 2017-11-15
Completion:: 2026-12-31

Conditions

Video Capsule Endoscopy
Esophageal Diseases

No Results Yet

NCT04057872 | COMPLETED | PHASE1

17 participants

Therapeutic Plasma Exchange in Adult Patients With Severe Sepsis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2020-10-21
Completion:: 2024-12-31

Conditions

Septic Shock

Interventions

PROCEDURE

No Results Yet

NCT04017299 | COMPLETED | NA

60 participants

Electronic Distraction for ICU Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2019-07-17
Completion:: 2019-12-31

Conditions

Adult ICU Patients

Interventions

OTHER

No Results Yet

NCT03914794 | COMPLETED | PHASE2

30 participants

A Study of Pemigatinib in Non-muscle Invasive Bladder Cancer Patients With Recurrent Low- or Intermediate-Risk Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2020-10-02
Completion:: 2025-09-30

Conditions

Bladder Cancer
NMIBC
Non-Muscle Invasive Bladder Cancer
Urothelial Carcinoma Recurrent

Interventions

DRUG

No Results Yet

NCT03909815 | COMPLETED | NA

1600 participants

Dual Mobility Cups in Hip Fracture Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2020-01-17
Completion:: 2025-09-24

Conditions

Femoral Neck Fractures

Interventions

DEVICE

No Results Yet

NCT03803735 | RECRUITING

10000 participants

Hospital Based Registry of Childhood Cancer in Pediatric Oncology Units in French Speaking Africa

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-03
Start Date:: 2016-01-01
Completion:: 2030-12-31

Conditions

Pediatric Cancer

No Results Yet

NCT03797378 | COMPLETED | NA

108 participants

Movement-2-Music: Lakeshore Examination of Activity, Disability, and Exercise Response Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2019-08-09
Completion:: 2023-05-25

Conditions

Spinal Cord Injuries
Traumatic Brain Injury
Spina Bifida
Cerebral Palsy
Stroke
Parkinson Disease
Multiple Sclerosis

Interventions

OTHER

No Results Yet

NCT03782636 | ACTIVE_NOT_RECRUITING | PHASE2

41 participants

Interleukin-2 Therapy of Autoimmunity in Diabetes (ITAD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2019-01-28
Completion:: 2023-02-16

Conditions

Type1 Diabetes

Interventions

DRUG
OTHER

No Results Yet

NCT03721822 | RECRUITING | PHASE1

100 participants

Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2018-10-23
Completion:: 2026-10-23

Conditions

Smoking, Cigarette
Smoking E-cigarette
Healthy Volunteer

Interventions

DRUG

No Results Yet

NCT03694171 | COMPLETED

450 participants

Access to Care and Prognosis in Elderly With Cancer (INCAPAC Study)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-03
Start Date:: 2013-11-30
Completion:: 2016-11-30

Conditions

Cancer

Interventions

OTHER

Results Available

NCT03676218 | COMPLETED

14 participants

Assessing Patient-reported & Patient-related Outcomes in Randomized Cancer Trials for Older Adults

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-03
Start Date:: 2017-09-01
Completion:: 2023-12-01

Conditions

Cancer

Interventions

OTHER

Results Available

NCT03620136 | COMPLETED | PHASE3

98 participants

Comparison of Two Techniques of Locoregional Analgesia in Total Knee Prosthesis Surgery : Block to the Adductor Channel Versus Peri-articular Local Infiltrations

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2018-02-07
Completion:: 2019-11-27

Conditions

Analgesic

Interventions

DRUG

No Results Yet

NCT03480438 | COMPLETED | PHASE2

52 participants

Treatment of Older Patients With B-precursor ALL With Sequential Dose Reduced Chemotherapy and Blinatumomab

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2018-06-01
Completion:: 2024-01-10

Conditions

B-Precursor ALL

Interventions

DRUG

No Results Yet

NCT03460483 | COMPLETED | NA

1001 participants

Universal Endometrial Cancer DNA Sequencing for Detection of Lynch Syndrome and Personalized Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2018-03-30
Completion:: 2025-06-15

Conditions

Relatives
Endometrial Adenocarcinoma
Endometrial Carcinoma
Lynch Syndrome

Interventions

OTHER
PROCEDURE

No Results Yet

NCT03378544 | COMPLETED | NA

220 participants

Engaging Traditional Birth Attendants to Reduce Maternal Depression in Rural Kenya

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2018-04-09
Completion:: 2019-08-31

Conditions

Depression

Interventions

BEHAVIORAL

No Results Yet

NCT03335995 | COMPLETED

364 participants

Stroke Prognosis in Intensive CarE

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-03
Start Date:: 2017-10-18
Completion:: 2019-11-18

Conditions

Acute Stroke Patients Requiring Invasive Mechanical Ventilation

No Results Yet

NCT03313908 | COMPLETED | NA

10 participants

Radioguided Occult Lesion Localisation by Indocyanine Green

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2017-10-17
Completion:: 2018-07-19

Conditions

Breast Cancer Female

Interventions

PROCEDURE

No Results Yet

NCT03282266 | COMPLETED | NA

128 participants

Safety and Efficacy of Pulmonary Artery Denervation in Patients With Pulmonary Arterial Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2018-01-18
Completion:: 2021-06-22

Conditions

Pulmonary Arterial Hypertension

Interventions

PROCEDURE

No Results Yet

NCT03270839 | COMPLETED | PHASE4

54 participants

Motion Sickness Medications and Vestibular Time Constant

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-03
Start Date:: 2017-06-01
Completion:: 2019-09-30

Conditions

Drug Reaction

Interventions

DRUG

No Results Yet