MedTrace Logo

Role of the Environment and Endocrine Disruptors in Child Cryptorchidism

NCT04342026 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1452

Last updated 2025-10-03

No results posted yet for this study

Summary

Cryptorchidism is the most frequent congenital defect of the male newborn. It requires surgery in childhood, increases the risk of fertility disorders and cancer. As a major public health objective, it's the subject of numerous recommendations. Its frequency is increasing in some countries faster than a single genetic cause could not explain it. It may occurs in a geographic cluster. The cause of cryptorchidism involves genetic, hormonal and environmental factors. Animal studies suggest that endocrine disruptors interfere with fetal testicular migration. The aim of the study is to find out if some environmental exposition may be associated with cryptorchidism.

Conditions

  • Cryptorchidism

Interventions

OTHER

Measure of the exposure of parent of male with /without cryptorchidism to endocrine disruptors

Measure of the exposure of parent of patient with/without cryptorchidism to endocrine disruptors (job exposure, during pregnancy)

Sponsors & Collaborators

  • University Hospital, Bordeaux

    collaborator OTHER

  • University Hospital, Montpellier

    lead OTHER

Eligibility

Min Age
1 Month
Max Age
18 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-04-16
Primary Completion
2027-10-15
Completion
2028-04-15

Countries

  • France

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04342026 on ClinicalTrials.gov