Clinical Trials Updated in 2025

NCT06126666 | RECRUITING | PHASE1

96 participants

A Study With ABL103 in Subjects With Advanced or Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2023-11-07
Completion:: 2025-12-30

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT06119594 | ACTIVE_NOT_RECRUITING | NA

90 participants

Contribution of the Evaluation of Body Composition by Connected Scale in the Effectiveness of a Reconditioning Program Through Physical Activity Adapted for Patients Suffering From Chronic Diseases

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2024-08-27
Completion:: 2026-06-01

Conditions

Chronic Disease

Interventions

DEVICE

No Results Yet

NCT06083090 | RECRUITING | NA

72 participants

Effects of Yoga Therapy in Rehabilitation Compared to Physiotherapy in Moderate Axial Spondyloarthritis (axSPA)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2024-08-27
Completion:: 2028-02-06

Conditions

Axial Spondyloarthritis (axSPA)

Interventions

PROCEDURE

No Results Yet

NCT06081114 | ACTIVE_NOT_RECRUITING | NA

643 participants

Micronutrient Dose Response Study in Bangladesh

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2023-10-22
Completion:: 2025-09-22

Conditions

Micronutrient Status

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06047834 | ACTIVE_NOT_RECRUITING | PHASE2

24 participants

Pharmacokinetic and Safety Study of Oral Lofexidine in Neonates Experiencing Opioid Withdrawal Due to Intrauterine Exposure to Opioids

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2023-10-02
Completion:: 2025-05-11

Conditions

Opioid Withdrawal (Disorder)

Interventions

DRUG
OTHER

No Results Yet

NCT06046287 | WITHDRAWN | PHASE2

0 participants

Daratumumab for Polyneuropathy Associated With MGUS

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-09-26
Completion:: 2025-09-26

Conditions

Peripheral Neuropathy
Monoclonal Gammopathy of Undetermined Significance

Interventions

DRUG

No Results Yet

NCT06043362 | RECRUITING | NA

375 participants

Use of Nicotine Pouches Among Daily Smokers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2024-09-17
Completion:: 2028-01-31

Conditions

Tobacco Dependence

Interventions

OTHER

No Results Yet

NCT06027151 | COMPLETED | NA

380 participants

Comparing the Efficacy of Metronidazole and Minocycline Gels for the Treatment of Diabetic Periodontitis Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2022-10-06
Completion:: 2023-07-31

Conditions

Periodontitis
Diabetes Mellitus

Interventions

DRUG

No Results Yet

NCT05997446 | ACTIVE_NOT_RECRUITING

610 participants

Amulet™ ADVANCE LAA

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-01
Start Date:: 2023-07-12
Completion:: 2027-06-30

Conditions

Atrial Fibrillation
Stroke
Bleeding

Interventions

DEVICE

No Results Yet

NCT05972967 | COMPLETED | PHASE2

12 participants

Safety and Efficacy of OMS906 in Paroxysmal Nocturnal Hemoglobinuria Patients With a Sub-optimal Response to Ravulizumab

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2023-03-27
Completion:: 2024-10-10

Conditions

Paroxysmal Nocturnal Hemoglobinuria

Interventions

BIOLOGICAL

No Results Yet

NCT05971251 | ACTIVE_NOT_RECRUITING | PHASE1

24 participants

Addition of Loncastuximab Tesirine to Acalbrutinib , Chronic Lymphocytic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2023-12-18
Completion:: 2026-12-31

Conditions

Chronic Lymphocytic Leukemia

Interventions

DRUG

No Results Yet

NCT05955456 | RECRUITING

600 participants

Detecting EARLY Heart Failure in Greater Manchester

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-01
Start Date:: 2023-10-09
Completion:: 2030-09-01

Conditions

Heart Failure

Interventions

OTHER

No Results Yet

NCT05932680 | RECRUITING | PHASE2

75 participants

Limited-duration Teclistamab

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2023-07-05
Completion:: 2026-06-30

Conditions

Myeloma Multiple

Interventions

OTHER

No Results Yet

NCT05874375 | RECRUITING | NA

20 participants

UCon Treatment of Overactive Bladder (OAB) in Males

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2023-10-12
Completion:: 2026-06-12

Conditions

Urinary Incontinence
Urge Incontinence
Nocturia
Urinary Frequency More Than Once at Night
Urinary Incontinence, Urge
Incontinence, Nighttime Urinary

Interventions

DEVICE

No Results Yet

NCT05835141 | COMPLETED

100 participants

Rates and Risk Factors of Contact Between the OTX-TIC Intracameral Ocular Implant and Corneal Endothelium

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-01
Start Date:: 2023-05-01
Completion:: 2024-01-30

Conditions

Corneal Endothelium

Interventions

OTHER

No Results Yet

NCT05821660 | COMPLETED | NA

64 participants

Fastreset Study: Metabolic Effects of a Five-day Remotely Delivered Hypocaloric and Ketogenic Program

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2023-04-01
Completion:: 2023-08-17

Conditions

Healthy Nutrition
Healthy Lifestyle

Interventions

OTHER

No Results Yet

NCT05809973 | COMPLETED

127 participants

The Oslo Study of Visual Impairment After Stroke (StrokeVIS)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-01
Start Date:: 2021-11-15
Completion:: 2024-05-21

Conditions

Stroke, Acute

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05775796 | COMPLETED | PHASE2

30 participants

Evaluate the Efficacy and Safety of Serplulimab Plus Chemotherapy in Neoadjuvant and Adjuvant Treatment of Resectable NSCLC (ECTOP-1013)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2023-03-15
Completion:: 2024-05-28

Conditions

Non-small Cell Lung Cancer
Stage II-IIIA
Immunotherapy
Neoadjuvant Therapy

Interventions

DRUG

No Results Yet

NCT05754216 | WITHDRAWN | NA

0 participants

Intraoperative Identification and Stimulation of the Glossopharyngeal Nerve

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-12-31
Completion:: 2027-03-31

Conditions

Head and Neck Cancer
Obstructive Sleep Apnea

Interventions

DEVICE

No Results Yet

NCT05699551 | WITHDRAWN | NA

0 participants

Supervised Exercise as a Therapeutic Strategy for Interstitial Cystitis/Bladder Pain Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2023-05-10
Completion:: 2025-09-30

Conditions

Interstitial Cystitis
Bladder Pain Syndrome

Interventions

BEHAVIORAL

No Results Yet

NCT05673993 | COMPLETED | PHASE3

381 participants

A Study to Evaluate the Efficacy and Safety of Telitacicept in Subjects With Active Primary Sjogren's Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2023-04-06
Completion:: 2024-10-29

Conditions

Primary Sjogren's Syndrome

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT05665426 | COMPLETED | NA

140 participants

Infrared Thermography-based Study of the Warming Effect Difference at Waist

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2023-04-14
Completion:: 2023-06-25

Conditions

Health

Interventions

OTHER

Results Available

NCT05658601 | COMPLETED

104 participants

A Study to Describe the Switching From a First- or Second-line Disease Modifying Therapy (DMT) to Ozanimod in Participants With Relapsing Remitting Multiple Sclerosis (RRMS)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-01
Start Date:: 2023-07-14
Completion:: 2025-07-03

Conditions

Multiple Sclerosis, Relapsing-Remitting

No Results Yet

NCT05646251 | COMPLETED | NA

33 participants

Intra-procedural Transthoracic EChocardiogram to Facilitate Left Bundle Branch Area Pacing (LBBAP)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2023-03-01
Completion:: 2024-06-24

Conditions

Heart Failure

Interventions

DEVICE

Results Available

NCT05615935 | COMPLETED | NA

74 participants

Experiential HIV Testing Increasing Testing Related Knowledge and Practice, and Reduce Stigma Toward HIV of Nurses.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2022-11-09
Completion:: 2023-02-01

Conditions

Hiv
HIV Testing

Interventions

OTHER

Results Available

NCT05610306 | COMPLETED

20 participants

Quality of Life in Middle-aged and Older Patients With Congenital Ichthyosis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-01
Start Date:: 2022-11-14
Completion:: 2023-07-31

Conditions

Congenital Ichthyosis

Interventions

OTHER

No Results Yet

NCT05604170 | TERMINATED | PHASE3

117 participants

Open-label Study of Adjunctive GNX Treatment in Children and Adults With TSC-related Epilepsy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2022-05-16
Completion:: 2025-04-02

Conditions

Tuberous Sclerosis Complex

Interventions

DRUG

Results Available

NCT05559892 | ACTIVE_NOT_RECRUITING | NA

100 participants

Conditional Cash Transfer Intervention to Improve T2DM

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2022-11-01
Completion:: 2026-11-30

Conditions

Type 2 Diabetes

Interventions

BEHAVIORAL

No Results Yet

NCT05526313 | COMPLETED | PHASE1

29 participants

Study of Purinostat Mesylate for Injection in the Treatment of Relapsed or Refractory B Cell-related Tumor-predominant

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2020-08-10
Completion:: 2022-09-07

Conditions

Diffuse Large B Cell Lymphoma，DLBCL

Interventions

DRUG

No Results Yet

NCT05523583 | COMPLETED

165 participants

Assessment of Tobacco Smoking and Alcohol Drinking and Treatment Outcomes Among Patients With Lung or Head and Neck Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-01
Start Date:: 2022-10-27
Completion:: 2025-09-18

Conditions

Lung or Head and Neck Cancer

Interventions

OTHER

No Results Yet

NCT05522959 | RECRUITING

100 participants

Cardio-Oncology Rehabilitation Exercise

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-01
Start Date:: 2022-03-14
Completion:: 2026-12-31

Conditions

Breast Cancer

No Results Yet

NCT05510895 | COMPLETED | PHASE2

2 participants

Neoadjuvant Encorafenib, Binimetinib and Cetuximab for Patients With BRAF V600E Mutated/pMMR Localized Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2022-09-01
Completion:: 2024-07-31

Conditions

Colorectal Cancer
Colon Cancer
BRAF V600E
BRAF V600 Mutation
Localized Cancer

Interventions

DRUG

No Results Yet

NCT05472038 | COMPLETED | PHASE2/PHASE3

1453 participants

A Study to Learn About New COVID-19 RNA Vaccine Candidates in COVID-19 Vaccine-Experienced Healthy Individuals

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2022-07-26
Completion:: 2024-03-26

Conditions

SARS-CoV-2 Infection
COVID-19

Interventions

BIOLOGICAL

Results Available

NCT05463666 | ACTIVE_NOT_RECRUITING

840 participants

STudying Ageing in Rheumatic Diseases (STAR)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-01
Start Date:: 2022-12-01
Completion:: 2025-04-22

Conditions

Rheumatoid Arthritis

Interventions

OTHER

No Results Yet

NCT05454956 | COMPLETED | PHASE2

39 participants

Pilot Study Comparing the Safety and Efficacy of Two Dosing Regimens of TP-03 for the Treatment of MGD

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2022-08-03
Completion:: 2023-05-18

Conditions

Meibomian Gland Dysfunction
Blepharitis
Demodex Infestation

Interventions

DRUG

Results Available

NCT05454943 | COMPLETED | NA

178 participants

Remote Time-restricted EAting DeliverY

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2022-07-07
Completion:: 2023-09-20

Conditions

Metabolic Disturbance

Interventions

BEHAVIORAL

No Results Yet

NCT05452928 | NOT_YET_RECRUITING | PHASE4

150 participants

Aciclovir Versus Placebo for HSV-2 Meningitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2026-06-01
Completion:: 2028-06-01

Conditions

Herpes Simplex 2
Meningitis, Viral

Interventions

DRUG

No Results Yet

NCT05447598 | ACTIVE_NOT_RECRUITING | NA

200 participants

Remote Monitoring After Heart Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2023-04-25
Completion:: 2025-09-30

Conditions

Heart Failure Acute
Remote Monitoring
Nurse's Role

Interventions

OTHER

No Results Yet

NCT05446870 | COMPLETED | PHASE2

160 participants

Pembrolizumab With Chemotherapy and MK-4830 for Treating Participants With Ovarian Cancer (MK-4830-002)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2022-07-25
Completion:: 2023-12-20

Conditions

High-grade Serous Ovarian Carcinoma
Ovarian Carcinoma

Interventions

BIOLOGICAL
DRUG

Results Available

NCT05431127 | COMPLETED | NA

34 participants

High Dose Inspiratory Muscle Training in LOPD

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2022-07-19
Completion:: 2025-01-01

Conditions

Late-Onset Pompe Disease
Lysosomal Disease

Interventions

DEVICE

No Results Yet