MedTrace Logo

Comparing the Efficacy of Metronidazole and Minocycline Gels for the Treatment of Diabetic Periodontitis Patients

NCT06027151 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 380

Last updated 2025-10-01

No results posted yet for this study

Summary

This clinical study randomized 380 diabetic chronic periodontitis patients into 4 groups: scaling and root planning alone (group I), scaling and root planning plus metronidazole gel (group II), scaling and root planning plus minocycline gel (group III), and scaling and root planning plus both metronidazole and minocycline gels (group IV). Periodontal measurements including probing depth, gingival color and texture, bleeding on probing, clinical attachment level, and recession were recorded at baseline, 7 days, and 15 days.

Conditions

Interventions

DRUG

1ml of 1% metronidazole gel

Subgingivally at baseline visit

DRUG

1ml of 2% minocycline gel

sub gingivally at baseline visit

DRUG

1ml of combination of 1% metronidazole gel and 2% minocycline

subgingivally at baseline visit

Sponsors & Collaborators

  • Riphah International University

    lead OTHER

Principal Investigators

  • Aeman Choudhary, BDS · Riphah International University, Rawalpindi

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-10-06
Primary Completion
2023-07-31
Completion
2023-07-31

Countries

  • Pakistan

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06027151 on ClinicalTrials.gov