Clinical Trials

NCT04544410 | TERMINATED | PHASE2

100 participants

A Ph2b to Evaluate Tildacerfont in the Reduction of Glucocorticoid Steroid Doses in Adult CAH

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2021-02-22

Completion:

2024-10-31

Conditions

• Congenital Adrenal Hyperplasia

Interventions

• DRUG

Results Available

NCT04501328 | ACTIVE_NOT_RECRUITING | NA

122 participants

A Randomized Controlled Trial of Coaching Into Care With VA-CRAFT to Promote Veteran Engagement in PTSD Care

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2021-04-01

Completion:

2026-08-31

Conditions

• Stress Disorders, Post-traumatic

Interventions

• BEHAVIORAL

No Results Yet

NCT04497584 | ACTIVE_NOT_RECRUITING | PHASE2

12 participants

Phase 2 Trial of Afatinib Plus Prednisone for Advanced Squamous NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2021-08-04

Completion:

2026-09-01

Conditions

• Advanced Squamous Non Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT04472949 | ACTIVE_NOT_RECRUITING | PHASE2

46 participants

Thoracic Radiotherapy Plus Maintenance Durvalumab After First Line Carboplatin and Etoposide Plus Durvalumab in Extensive-stage Disease Small Cell Lung Cancer (ED-SCLC).

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2021-06-25

Completion:

2027-12-31

Conditions

• Small Cell Lung Cancer
• Lung Cancer

Interventions

• DRUG
• RADIATION

No Results Yet

NCT04453657 | ENROLLING_BY_INVITATION | NA

270 participants

Tele-Wellness Supported App for Family Child Care Home Providers and Families to Promote Health, Family Engagement, and School Readiness Amid COVID-19

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2021-02-04

Completion:

2026-09-30

Conditions

• Stress, Psychological
• Child Behavior
• Social Competence

Interventions

• DEVICE

No Results Yet

NCT04442321 | COMPLETED | NA

60 participants

Ultrasound-Guided Percutaneous Electrical Stimulation on Radial Nerve in Patients With Lateral Epicondylalgia

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2020-09-01

Completion:

2023-06-01

Conditions

• Tennis Elbow

Interventions

• OTHER

No Results Yet

NCT04409405 | COMPLETED

787 participants

Evaluation and Support to EVD Cured Patients and Their Contacts (Les Vainqueurs d'Ebola)

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-01

Start Date:

2020-04-16

Completion:

2021-10-18

Conditions

• Ebola Virus Disease

No Results Yet

NCT04408885 | RECRUITING

400 participants

Rehabilitation Treatment of Anterior Cruciate Ligament Rupture

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-01

Start Date:

2020-08-15

Completion:

2027-12-31

Conditions

• ACL Injury

Interventions

• OTHER

No Results Yet

NCT04361708 | RECRUITING | PHASE1

54 participants

Safety of Combining Irinotecan With 5-FU, Leucovorin/Folinic Acid, Oxaliplatin, and Docetaxel Chemotherapies

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2020-05-08

Completion:

2026-06-30

Conditions

• Pancreatic Adenocarcinoma
• Gastroesophageal Junction Adenocarcinoma
• Adenocarcinoma

Interventions

• DRUG

No Results Yet

NCT04340531 | ACTIVE_NOT_RECRUITING | NA

810 participants

Effectiveness of a Multi-Level Smoking Cessation Program for High-Risk Women in Rural Communities

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2021-01-30

Completion:

2025-03-13

Conditions

• Tobacco-Related Carcinoma

Interventions

• OTHER

No Results Yet

NCT04300335 | SUSPENDED | NA

45 participants

The Feasibility and Effects of Exercise on Patients Suffering From Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2026-03-31

Completion:

2026-10-31

Conditions

• Multiple Myeloma

Interventions

• OTHER

No Results Yet

NCT04295863 | RECRUITING | PHASE1

264 participants

Comparing Dosing Intervals of Nivolumab or Pembrolizumab in Locally Advanced or Metastatic Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2020-06-25

Completion:

2026-04-12

Conditions

• Metastatic Cancer

Interventions

• DRUG

No Results Yet

NCT04294043 | RECRUITING | PHASE1

40 participants

IV Gallium Study for Patients With Cystic Fibrosis Who Have NTM (ABATE Study)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2021-06-17

Completion:

2027-03-31

Conditions

• Nontuberculous Mycobacterium Infection

Interventions

• DRUG

No Results Yet

NCT04280497 | RECRUITING | NA

1800 participants

Rapid Recognition of Corticosteroid Resistant or Sensitive Sepsis

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2020-04-10

Completion:

2025-12-31

Conditions

• Sepsis

Interventions

• DRUG

No Results Yet

NCT04261673 | ACTIVE_NOT_RECRUITING | NA

120 participants

Prospective Randomized Evaluation of Decompressive Ipsilateral Craniectomy for Traumatic Acute Epidural Hematoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2020-05-23

Completion:

2025-09-14

Conditions

• Epidural Hematoma
• Brain Herniation
• Decompressive Craniectomy
• Craniotomy

Interventions

• PROCEDURE

No Results Yet

NCT04260126 | COMPLETED | PHASE2

95 participants

Study of PDS0101 and Pembrolizumab Combination I/O in Subjects With HPV16 + Recurrent and/or Metastatic HNSCC

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2021-03-29

Completion:

2025-05-14

Conditions

• Metastatic Head and Neck Cancer
• Recurrent Head and Neck Cancer
• HPV Positive Oropharyngeal Squamous Cell Carcinoma
• Neoplasms, Head and Neck

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT04234997 | COMPLETED | PHASE2

14 participants

Suvorexant to Reduce Symptoms of Nicotine Use

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2021-08-23

Completion:

2024-08-22

Conditions

• Smoking Cessation

Interventions

• DRUG

Results Available

NCT04229979 | ACTIVE_NOT_RECRUITING | PHASE3

127 participants

Galinpepimut-S Versus Investigator's Choice of Best Available Therapy for Maintenance in AML CR2/CRp2

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2021-02-08

Completion:

2025-12-31

Conditions

• Acute Myeloid Leukemia

Interventions

• BIOLOGICAL
• DRUG
• OTHER

No Results Yet

NCT04209504 | RECRUITING

60 participants

Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-01

Start Date:

2021-10-12

Completion:

2026-08-31

Conditions

• Shoulder Surgery
• Shoulder Pain
• Shoulder Injuries
• Shoulder Arthritis
• Shoulder Disease
• Rotator Cuff Tears
• Rotator Cuff Injuries
• Rotator Cuff Arthropathy of Left Shoulder
• Rotator Cuff Arthropathy of Right Shoulder
• Rotator Cuff Repair

Interventions

• DIAGNOSTIC_TEST
• DRUG
• DEVICE

No Results Yet

NCT04198987 | COMPLETED

20 participants

Dietary Monosaccharide Supplementation in Patients With Congenital Disorders of Glycosylation

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-01

Start Date:

2018-12-06

Completion:

2025-06-11

Conditions

• Congenital Disorder of Glycosylation

No Results Yet

NCT04174924 | COMPLETED

126 participants

Molecular Background of Endothelial Cell Loss in Patients With Phakic Intraocular Lenses: a Tear and Aqueous Humour Analysis Study

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-01

Start Date:

2020-07-02

Completion:

2025-02-01

Conditions

• Cataract
• Phakic Intraocular Lens Explantation

Interventions

• PROCEDURE

No Results Yet

NCT04132362 | RECRUITING

1080 participants

Benefits of Personalised Music in Dementia - a Feasibility Study

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-01

Start Date:

2019-11-28

Completion:

2026-04-30

Conditions

• Dementia

Interventions

• BEHAVIORAL

No Results Yet

NCT04123457 | ENROLLING_BY_INVITATION

100 participants

Biorepository of Biomarkers for Optimization of Microvascular Treatment of Lymphedema

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-01

Start Date:

2019-08-01

Completion:

2026-08-31

Conditions

• Lymphedema

No Results Yet

NCT04109053 | WITHDRAWN

0 participants

Ultrasensitive Electroanatomic Mapping to Adjudicate Endpoints for Ablation In Paroxysmal AF Patients Using Cryoballoon

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-01

Start Date:

2020-03-02

Completion:

2021-03-31

Conditions

• Paroxysmal Atrial Fibrillation

No Results Yet

NCT04108858 | TERMINATED | PHASE1/PHASE2

2 participants

Testing the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Maintenance Treatment (Trastuzumab and Pertuzumab) After Initial Chemotherapy in a Phase Ib/II Trial for Advanced HER2 Positive Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2021-05-20

Completion:

2022-04-29

Conditions

• Anatomic Stage IV Breast Cancer AJCC v8
• HER2-Positive Breast Carcinoma
• Metastatic Breast Carcinoma

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT04075084 | RECRUITING

1400 participants

Observation of Clinical Routine Care for Patients With BIOTRONIK Implantable Cardiac Monitors (ICMs)

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-01

Start Date:

2019-10-28

Completion:

2027-05-30

Conditions

• Tachycardia
• Atrial Fibrillation
• Syncope
• Bradycardia
• Cryptogenic Stroke

No Results Yet

NCT04041778 | COMPLETED

17 participants

'Understanding the Electrophysiological Substrate Underlying Persistent Atrial Fibrillation Study II (USURP AF- Study II)'

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-01

Start Date:

2019-07-25

Completion:

2024-09-30

Conditions

• Atrial Fibrillation Mechanisms
• Persistent Atrial Fibrillation
• Substrate Ablation
• Pulmonary Vein Isolation
• Non-contact Mapping

Interventions

• OTHER

No Results Yet

NCT04007276 | NOT_YET_RECRUITING | PHASE4

60 participants

The Effect of Lumify™ on Ocular Redness, Intraocular Pressure, and Eyelid Position in Glaucoma Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2026-11-10

Completion:

2031-06-01

Conditions

• Glaucoma
• Glaucoma, Open-Angle
• Glaucoma; Drugs
• Droopy Eyelid
• Ptosis
• Glaucoma, Primary Open Angle

Interventions

• DRUG
• OTHER

No Results Yet

NCT04001777 | ACTIVE_NOT_RECRUITING | PHASE1

80 participants

A Study of APG-1252 Plus Osimertinib(AZD9291) in EGFR TKI Resistant NSCLC Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2019-07-04

Completion:

2025-12-31

Conditions

• EGFR Positive Non-small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT04000152 | TERMINATED | NA

296 participants

RCT Study to Validate niPGT-A Clinical Benefit.

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2020-06-29

Completion:

2025-04-18

Conditions

• Aneuploidy
• Chromosome Abnormality
• Infertility

Interventions

• DIAGNOSTIC_TEST
• OTHER

No Results Yet

NCT03993873 | ACTIVE_NOT_RECRUITING | PHASE1

95 participants

Study of TPX-0022 in Patients With Advanced NSCLC, Gastric Cancer or Solid Tumors Harboring Genetic Alterations in MET

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2019-09-05

Completion:

2024-01-08

Conditions

• Advanced Solid Tumor
• Metastatic Solid Tumors
• MET Gene Alterations

Interventions

• DRUG

No Results Yet

NCT03985345 | COMPLETED | NA

55 participants

Prospective Evaluation of the Connected EMY Biofeedback Probe in the Management of Stress Urinary Incontinence.

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2019-09-02

Completion:

2020-09-09

Conditions

• Stress Urinary Incontinence

Interventions

• DEVICE

No Results Yet

NCT03946215 | COMPLETED | NA

8 participants

Cardiorespiratory Responses to Treadmill Running at Different Slopes

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2018-09-01

Completion:

2018-12-17

Conditions

• Cardiorespiratory Responses
• Well-trained Athletes

Interventions

• OTHER

No Results Yet

NCT03925025 | COMPLETED | PHASE3

1728 participants

Effectiveness of Calcium Channel Blockade for OP and Carbamate Pesticide Poisoning

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2020-06-11

Completion:

2025-03-31

Conditions

• Anticholinesterase Insecticide Poisoning
• Pesticide Poisoning

Interventions

• DRUG

No Results Yet

NCT03857919 | COMPLETED | NA

235 participants

TearCare System to Treat Dry Eye Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2019-03-03

Completion:

2020-02-17

Conditions

• Dry Eye
• Meibomian Gland Dysfunction

Interventions

• DEVICE

Results Available

NCT03761173 | COMPLETED

1200 participants

FlowTriever All-Comer Registry for Patient Safety and Hemodynamics

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-01

Start Date:

2018-12-15

Completion:

2024-09-04

Conditions

• PE - Pulmonary Embolism
• PE - Pulmonary Thromboembolism

Interventions

• DEVICE
• DRUG

Results Available

NCT03744156 | COMPLETED | NA

131 participants

Sleep and Pain Interventions in Women With Fibromyalgia

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2019-02-07

Completion:

2025-05-31

Conditions

• Fibromyalgia
• Insomnia
• Chronic Widespread Pain

Interventions

• BEHAVIORAL

No Results Yet

NCT03688503 | COMPLETED | NA

59 participants

Magnesium Supplementation and Blood Pressure Reduction

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2019-02-15

Completion:

2020-01-09

Conditions

• Blood Pressure

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT03687723 | COMPLETED

93 participants

Observational Study of the Clinical Use of the OCS™ Heart

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-01

Start Date:

2016-10-31

Completion:

2024-12-31

Conditions

• Heart Transplantation

Interventions

• DEVICE

No Results Yet

NCT03563248 | ACTIVE_NOT_RECRUITING | PHASE2

168 participants

Losartan and Nivolumab in Combination With FOLFIRINOX and SBRT in Localized Pancreatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-01

Start Date:

2018-08-10

Completion:

2022-02-16

Conditions

• Pancreatic Cancer

Interventions

• DRUG
• RADIATION
• PROCEDURE

No Results Yet