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The Effect of Lumify™ on Ocular Redness, Intraocular Pressure, and Eyelid Position in Glaucoma Patients

NCT04007276 · Status: NOT_YET_RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2025-10-01

No results posted yet for this study

Summary

Glaucoma represents a group of conditions that cause damage to the optic nerve and can lead to irreversible vision loss. Current treatments are aimed at lowering intraocular pressure while minimizing medication side effects. Lumify™ (Brimonidine Tartrate Ophthalmic Solution 0.025%) is an FDA-approved medication for alleviating eye redness, a common side effect of glaucoma medications. The purpose of this study is to evaluate the effect of Lumify™ on eye redness, intraocular pressure, and eyelid position in patients with glaucoma who are already using the Brimonidine 0.1%, 0.15% or 0.2% eye drops.

Conditions

  • Glaucoma
  • Glaucoma, Open-Angle
  • Glaucoma; Drugs
  • Droopy Eyelid
  • Ptosis
  • Glaucoma, Primary Open Angle

Interventions

DRUG

brimonidine tartrate ophthalmic solution 0.025%

Single dose of brimonidine tartrate ophthalmic solution 0.025% applied as an eye drop to the eye surface.

OTHER

sterile balanced saline solution

Single dose of sterile balanced saline solution applied as an eye drop to the eye surface.

Sponsors & Collaborators

  • Tulane University

    lead OTHER

Principal Investigators

  • Ze Zhang, MD · Tulane University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-11-10
Primary Completion
2031-06-01
Completion
2036-06-01
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04007276 on ClinicalTrials.gov