Clinical Trials Updated in 2025

NCT07098663 | RECRUITING | PHASE2

68 participants

Food Effect, Efficacy and Safety of MKP10241 in Healthy and Obese Adult Participants, With and Without Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-08-12
Completion:: 2026-01-19

Conditions

Type 2 Diabetes Mellitus (T2DM)
Food Effect
Safety and Tolerability
Obesity

Interventions

DRUG

No Results Yet

NCT07098312 | NOT_YET_RECRUITING | NA

80 participants

Impact of Creative Drama on Nursing Students' Cultural Competence

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-11-30
Completion:: 2026-01-31

Conditions

Cultural Competency

Interventions

BEHAVIORAL

No Results Yet

NCT07075237 | NOT_YET_RECRUITING | PHASE4

120 participants

Efficacy and Functional Recovery After Switching From Paliperidone Palmitate Injection to Oral Antipsychotics in Schizophrenia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-10-31
Completion:: 2026-10-31

Conditions

Schizophrenia

Interventions

DRUG

No Results Yet

NCT07057258 | ENROLLING_BY_INVITATION | NA

128 participants

Injection Versus Suture Repair of Laryngeal Clefts

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-09-01
Completion:: 2026-09-01

Conditions

Laryngeal Cleft
Dysphagia

Interventions

PROCEDURE

No Results Yet

NCT07050563 | NOT_YET_RECRUITING | NA

316 participants

Clinical Evaluation of the Tiaoshen Anti-Cancer Regimen in Treating Psycho-Neurological Symptom Cluster in Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-10-06
Completion:: 2028-09-01

Conditions

Cancer
Cancer Symptom Clusters

Interventions

DRUG
COMBINATION_PRODUCT

No Results Yet

NCT07041359 | RECRUITING | PHASE4

120 participants

Pre-trial of Clinical Trial of Traditional Chinese Medicine Treatment for Elderly Patients With Coronary Heart Disease Who Are Still Symptomatic After Optimal Medical Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-08-18
Completion:: 2026-12-31

Conditions

Coronary Arterial Disease (CAD)

Interventions

DRUG

No Results Yet

NCT07041164 | RECRUITING

174 participants

Diagnostic Performance and Children's Acceptance of Near-Infrared Light Transillumination and Bitewing Radiographs for Detecting Proximal Cavitation in Primary Molars of Patients Aged 4 to 10 Years

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-08-01
Completion:: 2026-03-30

Conditions

Dental Caries (Diagnosis)
Diagnostic Imaging
Optical Imaging
Radiographic Image Interpretation, Computer-Assisted
Proximal Dental Caries
Tooth, Deciduous

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07036159 | RECRUITING | PHASE2

238 participants

A Study to Assess the Safety and Immunogenicity of a Vaccine Against Malaria in Healthy Children Aged 5-60 Months

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-08-06
Completion:: 2027-04-23

Conditions

Malaria

Interventions

BIOLOGICAL

No Results Yet

NCT07030764 | RECRUITING | NA

448 participants

Comparison of Arthrogenic Muscle Inhibition (AMI) After ACL Reconstruction in Patients With Conventional Rehabilitation or Conventional Rehabilitation Combined With Digital Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-07-25
Completion:: 2027-06-30

Conditions

ACL - Anterior Cruciate Ligament Rupture

Interventions

DEVICE
BEHAVIORAL

No Results Yet

NCT07020234 | COMPLETED | NA

2040 participants

National Survey to Understand Ethical, Legal and Social Issues in Communicating to the Public About Epigenetics

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-06-12
Completion:: 2025-07-18

Conditions

Healthy

Interventions

BEHAVIORAL

No Results Yet

NCT07010107 | RECRUITING | PHASE3

500 participants

A Clinical Trial of Anaprazole for Treating Reflux Esophagitis.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-07-30
Completion:: 2026-04-30

Conditions

Reflux Esophagitis (RE)

Interventions

DRUG

No Results Yet

NCT07000279 | RECRUITING | NA

10 participants

Assessment of Feasibility, Functionality and Usability of an Hybrid Assistive Exoskeleton for Upper Limb

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-09-05
Completion:: 2025-12-31

Conditions

Upper Limb Deficits

Interventions

DEVICE

No Results Yet

NCT06996678 | COMPLETED | NA

14 participants

Effect of Virtual Reality on Cognitive Skills

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-07-01
Completion:: 2025-08-01

Conditions

Virtual Reality

Interventions

BEHAVIORAL

No Results Yet

NCT06979076 | NOT_YET_RECRUITING | PHASE1/PHASE2

12 participants

A Phase Ib Study of the Selective PKC-β Inhibitor MS-553 in Patients With Refractory or Relapsed CLL/SLL

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2026-07-31
Completion:: 2028-09-30

Conditions

CLL (Chronic Lymphocytic Leukemia)
SLL (Small Lymphocytic Lymphoma)

Interventions

DRUG

No Results Yet

NCT06962930 | RECRUITING | NA

40 participants

An Online Physical Activity Coaching Intervention for People With PD in Qatar

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-09-10
Completion:: 2026-05-10

Conditions

Parkinson Disease

Interventions

OTHER

No Results Yet

NCT06953375 | RECRUITING | NA

3250 participants

Implementation of Neuromuscular Electrical Stimulation After Total Knee Arthroplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-05-12
Completion:: 2029-04-30

Conditions

Total Knee Arthroplasty
Functional Recovery
Aging
Physical Therapy

Interventions

PROCEDURE
OTHER

No Results Yet

NCT06941129 | RECRUITING | PHASE1

12 participants

CAR T-cell Therapy Targeting CD19 and BCMA in Patients With Relapse/Refractory Autoimmune Diseases

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-02-11
Completion:: 2028-02-18

Conditions

Systemic Lupus Erythematosus
Systemic Sclerosis (SSc)
Inflammatory Myopathy
ANCA-Associated Vasculitis (AAV)
Connective Tissue Disease-Associated Thrombocytopenia
SLE-ITP

Interventions

BIOLOGICAL

No Results Yet

NCT06910033 | NOT_YET_RECRUITING

200 participants

Long-term Safety and Performance of CMF Porous Titanium Implants

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-11-30
Completion:: 2026-11-30

Conditions

Craniofacial Defects

Interventions

DEVICE

No Results Yet

NCT06896188 | RECRUITING | PHASE1

12 participants

9-ING-41 Combined With Retifanlimab, Plus Modified FOLFIRINOX for Patients With Advanced Pancreatic Adenocarcinoma (RiLEY)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-09-22
Completion:: 2027-09-30

Conditions

Pancreatic Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT06881602 | NOT_YET_RECRUITING | NA

20 participants

Remote Clinical Monitoring After Robotic Distal Pancreatectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-10-01
Completion:: 2026-12-31

Conditions

Digital Health

Interventions

PROCEDURE

No Results Yet

NCT06873152 | COMPLETED | NA

130 participants

Improvement of Operating Room Efficiency in Bilateral Wisdom Teeth Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-03-10
Completion:: 2025-05-27

Conditions

Third Molars Extraction

Interventions

PROCEDURE

No Results Yet

NCT06866171 | NOT_YET_RECRUITING

100 participants

Swivel Convertible Child Safety Seat to Improve Usage

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-12-31
Completion:: 2026-05-31

Conditions

Motor Vehicle Injury

Interventions

OTHER

No Results Yet

NCT06798649 | NOT_YET_RECRUITING | NA

318 participants

Effect of Visual Presentation of Atherosclerotic Plaque on Modification of Arterial Hypertension One Year Postpartum in Women With a History of Adverse Pregnancy Outcomes, and Risk Customization With AI Prediction Algorithms

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2026-06-01
Completion:: 2028-12-31

Conditions

Adverse Pregnancy Outcomes
Cardiovascular Diseases

Interventions

OTHER

No Results Yet

NCT06766864 | COMPLETED | PHASE1

32 participants

A Study of Subcutaneous DR-01 in Healthy Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-03-03
Completion:: 2025-08-27

Conditions

Healthy Volunteer

Interventions

DRUG
OTHER

No Results Yet

NCT06753838 | RECRUITING

100 participants

Choice of Anticoagulant for Primary Hemostasis Studies With PFA200® (Platelet Function Analyser)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-01-21
Completion:: 2025-12-31

Conditions

Hemostasis

Interventions

BIOLOGICAL

No Results Yet

NCT06731855 | RECRUITING

30 participants

An Exploratory Physiological Study of Post-operative Recovery in Surgical Neonates and Dimethylarginine:Arginine Levels

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-02-05
Completion:: 2026-02-28

Conditions

Gastroschisis
Congenital Diaphragmatic Hernia
Duodenal Atresia
Oesophageal Atresia With Tracheo-Oesophageal Fistula
Oesophageal Atresia
Exomphalos

Interventions

PROCEDURE

No Results Yet

NCT06730932 | NOT_YET_RECRUITING | PHASE2

31 participants

A Prospective，Single Arm, Multicenter Clinical Study of BTLA Monoclonal Antibody JS004 (B/T Lymphocyte Attenuator Factor Monoclonal Antibody) in Combination With Toripalimab in Patients With Unresectable or Advanced Renal Cell Carcinoma Who Had Failed Previous Immunotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-10-30
Completion:: 2026-10-30

Conditions

Unresectable or Advanced Clear Cell Renal Cell Carcinoma That Has Progressed After Previous Immunotherapy

Interventions

DRUG

No Results Yet

NCT06691854 | COMPLETED | NA

124 participants

Women's Perception of Respectful Maternity Care, Birth Experiences and Perception of Traumatic Birth

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-12-01
Completion:: 2025-07-01

Conditions

Maternity
Birth, First
Traumatic Birth
Intrapartum Fetal Distress

Interventions

OTHER

No Results Yet

NCT06681740 | RECRUITING | NA

72 participants

Effectiveness of Inspiratory Muscle Training for People With Ischemic Heart Disease Revascularized by Percutaneous Transluminal Coronary Angioplasty.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-11-11
Completion:: 2026-03-31

Conditions

Myocardial Ischemia
Coronary Arterial Disease (CAD)

Interventions

DEVICE

No Results Yet

NCT06649045 | ACTIVE_NOT_RECRUITING | PHASE3

600 participants

A Master Protocol for Orforglipron in Participants With Obstructive Sleep Apnea and Obesity or Overweight

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-10-22
Completion:: 2026-11-30

Conditions

OSA
Overweight or Obesity

Interventions

DRUG

No Results Yet

NCT06634277 | COMPLETED | NA

32 participants

Philly NavSTAR Implementation Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-08-09
Completion:: 2025-07-26

Conditions

Opioid Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06624930 | RECRUITING | NA

236 participants

Behaviour Change for Cancer Survivors Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-10-03
Completion:: 2028-05-31

Conditions

Cancer
Exercise

Interventions

OTHER

No Results Yet

NCT06593756 | RECRUITING | NA

30 participants

Hemodynamic Monitoring and Fluid Responsiveness in Venoarterial Extracorporeal Membrane Oxygenation (VA ECMO) - "HemodynamECMOnitoring-VA Study"

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-05-03
Completion:: 2027-01-31

Conditions

ECMO Treatment
ARDS
Pneumonia
Intensive Care
Hemodynamic Monitoring
Fluid Responsiveness

Interventions

DEVICE
DIAGNOSTIC_TEST
DRUG

No Results Yet

NCT06593717 | RECRUITING | NA

30 participants

Hemodynamic Monitoring and Fluid Responsiveness in Venovenous Extracorporeal Membrane Oxygenation (VV ECMO) - "HemodynamECMOnitoring-VV Study"

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-05-03
Completion:: 2027-01-31

Conditions

ECMO Treatment
ARDS
Pneumonia
Intensive Care
Hemodynamic Monitoring
Fluid Responsiveness

Interventions

DEVICE
DIAGNOSTIC_TEST
DRUG

No Results Yet

NCT06578897 | COMPLETED

118 participants

A Post-Market, Retrospective Study on 3D Metal Tibial and Femoral Cones

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-02-13
Completion:: 2025-02-13

Conditions

Total Knee Arthroplasty

Interventions

DEVICE

No Results Yet

NCT06578390 | RECRUITING | NA

500 participants

Efficacy Investigation of the Medical Device Apneal® on Smartphone for Sleep Apnea-Hypopnea Syndrome Diagnosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-03-26
Completion:: 2025-11-30

Conditions

Sleep Apnea Syndromes

Interventions

DEVICE

No Results Yet

NCT06549764 | COMPLETED | NA

297 participants

The YAM-project (Youth Aware of Mental Health)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-08-08
Completion:: 2025-02-18

Conditions

Prevention, Suicide

Interventions

BEHAVIORAL

No Results Yet

NCT06546189 | RECRUITING | NA

100 participants

Oral Lactobacillus Supplementation as Treatment for Overactive Bladder Syndrome: A Randomised Controlled Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2025-04-01
Completion:: 2027-03-31

Conditions

Overactive Bladder Syndrome

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT06540521 | RECRUITING

75 participants

Bolt CSP-M Holter Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-08-13
Completion:: 2026-06-30

Conditions

Heart Failure
Bradycardia

Interventions

OTHER

No Results Yet

NCT06534437 | RECRUITING | PHASE2

178 participants

MEN1703 (SEL24) to Treat Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma (JASPIS-01)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2024-12-05
Completion:: 2026-12-31

Conditions

Non-Hodgkin Lymphoma, B-cell

Interventions

DRUG

No Results Yet