Clinical Trials Updated in 2025

NCT05642676 | WITHDRAWN | NA

0 participants

Welcoming by Design Pilot: Reducing Structural Stigma by Changing Clinic Systems and Architectural Design

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2024-07-30
Completion:: 2027-07-30

Conditions

Hiv

Interventions

OTHER

No Results Yet

NCT05642208 | ACTIVE_NOT_RECRUITING | PHASE4

256 participants

Dupilumab Step-down Strategy to Maintain Remission in Adult and Adolescents Patients With Atopic Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2023-03-08
Completion:: 2026-09-08

Conditions

Atopic Dermatitis
Eczema, Atopic

Interventions

DRUG

No Results Yet

NCT05579015 | ACTIVE_NOT_RECRUITING | NA

170 participants

Predicting Illness Trajectories In Fully Remitted Major Depression Using Concurrent TBS/fNIRS

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2023-10-08
Completion:: 2026-12-31

Conditions

Major Depression in Remission
Healthy

Interventions

DEVICE
OTHER

No Results Yet

NCT05578053 | RECRUITING

420 participants

Efficacy and Safety of Dalpiciclib in Hormone Receptor-positive Advanced Breast Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-11
Start Date:: 2024-09-13
Completion:: 2028-12-01

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT05539131 | COMPLETED | NA

198 participants

Demonstration Study of the Effect of the Transcranial Direct Current Stimulation (tDCS) on Depressed Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2022-11-04
Completion:: 2024-10-31

Conditions

Depression

Interventions

DEVICE

Results Available

NCT05519254 | RECRUITING | PHASE3

600 participants

Lactoferrin and Lysozyme Supplementation for Long-term Diarrhea Sequelae

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2023-03-10
Completion:: 2026-07-31

Conditions

Diarrhea
Wasting
Malnutrition, Child

Interventions

DIETARY_SUPPLEMENT
COMBINATION_PRODUCT
OTHER

No Results Yet

NCT05510492 | COMPLETED | NA

95 participants

Effect of Training on IM Injection Practices

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2019-02-01
Completion:: 2022-09-08

Conditions

Injections

Interventions

OTHER

No Results Yet

NCT05399875 | ACTIVE_NOT_RECRUITING | NA

20 participants

AR Ruler to Improve Safety and Clinical Workflow During PICC Placement

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2022-09-26
Completion:: 2025-02-24

Conditions

Insertion of Peripherally Inserted Central Catheter

Interventions

OTHER

No Results Yet

NCT05388591 | COMPLETED | NA

171 participants

Evaluation of Musicotherapy on Pain During Wound Closure in the Emergency Department

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2022-06-14
Completion:: 2023-02-20

Conditions

Wounds Injuries

Interventions

OTHER

No Results Yet

NCT05385770 | COMPLETED | PHASE3

890 participants

Study to Evaluate and Compare the Efficacy and Safety of AZM and AML Combined and Alone in Mild-to-moderate Essential Hypertensive Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2022-07-08
Completion:: 2024-07-11

Conditions

Essential Hypertension

Interventions

DRUG

No Results Yet

NCT05382897 | COMPLETED | NA

42 participants

Fasting-mimicking Diet in Treatment of Depressive Symptoms in IBD

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2022-07-01
Completion:: 2025-02-02

Conditions

Inflammatory Bowel Diseases
Crohn Disease
Ulcerative Colitis

Interventions

OTHER

No Results Yet

NCT05357651 | RECRUITING | PHASE1

100 participants

A Study to Assess the Safety and Efficacy of LB1410 in Participants With Advanced Solid Tumor or Lymphoma（Keyplus-001）

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2022-08-12
Completion:: 2026-12-30

Conditions

Solid Tumor
Lymphoma

Interventions

DRUG

No Results Yet

NCT05305859 | RECRUITING | PHASE2

30 participants

Venetoclax Combining Chidamide and Azacitidine (VCA) in the Treatment of R/R AML

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2022-01-12
Completion:: 2026-01-31

Conditions

Leukemia, Myeloid, Acute
Relapsed Adult AML
Refractory Leukemia

Interventions

DRUG

No Results Yet

NCT05297383 | WITHDRAWN | NA

0 participants

Combining HIIT and n-3 PUFA Supplementation to Reduce Inflammation and Improve Metabolic Health (HIIT&PUFA)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2022-04-01
Completion:: 2022-06-01

Conditions

Obesity
Inflammation
Insulin Resistance
Dyslipidemias
Gut Microbiome

Interventions

DIETARY_SUPPLEMENT
BEHAVIORAL

No Results Yet

NCT05295719 | COMPLETED | NA

129 participants

Combining HIIT and n-3 PUFA to Reduce Inflammation and Improve Metabolic Health

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2022-09-01
Completion:: 2024-12-31

Conditions

Obesity
Inflammation
Human Microbiome
Insulin Resistance
Dyslipidemias

Interventions

DIETARY_SUPPLEMENT
BEHAVIORAL

No Results Yet

NCT05259709 | RECRUITING | PHASE1

50 participants

A Study of ImmunoPet Imaging Using 89Zr-DFO-REGN5054 in Adult Participants With Solid Cancers Treated With Cemiplimab

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2023-02-07
Completion:: 2027-01-06

Conditions

Advanced Solid Tumor
Metastatic Solid Tumor

Interventions

DRUG

No Results Yet

NCT05233761 | COMPLETED | PHASE2

125 participants

Evaluation of an Oral Cannabidiol (CBD)-Terpene Formulation on Sleep Physiology in Participants With Insomnia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2022-02-18
Completion:: 2022-07-02

Conditions

Insomnia

Interventions

DRUG

Results Available

NCT05231668 | TERMINATED | PHASE1

16 participants

Single Ascending Dose Study of SAR439459 in Adults With Osteogenesis Imperfecta (OI)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2022-08-25
Completion:: 2024-11-12

Conditions

Osteogenesis Imperfecta

Interventions

DRUG

No Results Yet

NCT05224375 | COMPLETED | NA

29 participants

A Trial Evaluating the Safety and Effectiveness of the Laminar Left Atrial Appendage Closure System in Subjects With Non-Valvular Atrial Fibrillation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2021-12-09
Completion:: 2023-04-05

Conditions

Atrial Fibrillation

Interventions

DEVICE

No Results Yet

NCT05219162 | COMPLETED | PHASE4

182 participants

Real-World Study on Gene Profile in Patients With Advanced NSCLC Who Progressed on First-Line Osimertinib Therapy(GPS).

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2022-02-25
Completion:: 2024-04-29

Conditions

Advanced NSCLC

Interventions

GENETIC

Results Available

NCT05146336 | RECRUITING

3000 participants

CytOSorb TreatMent Of Critically Ill PatientS Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-11
Start Date:: 2022-06-22
Completion:: 2032-06-30

Conditions

Septic Shock
Acute Respiratory Distress Syndrome
Trauma
Rhabdomyolysis
Cardiogenic Shock
Pancreatitis
Acute on Chronic Liver Failure
Acute Liver Failure
Burns
Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Cytokine Release Syndrome (CRS)
Extracorporeal Life Support
Postoperative Endocarditis
Hemophagocytic Lymphohistiocytoses
Liver Transplant; Complications
Infectious Disease
Postoperative Vasoplegic Syndrome
Drug Overdose
Sepsis

Interventions

DEVICE

No Results Yet

NCT05144945 | COMPLETED | PHASE3

301 participants

Study Describing the Immunogenicity and Safety of Quadrivalent Recombinant Influenza Vaccine (RIV4) Versus a Licensed Quadrivalent-inactivated Influenza Vaccine (IIV4) (Fluarix® Quadrivalent) in Participants 18 Years of Age and Older in South Korea

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2021-12-07
Completion:: 2022-09-01

Conditions

Influenza (Healthy Volunteers)

Interventions

BIOLOGICAL

Results Available

NCT05091190 | ACTIVE_NOT_RECRUITING | NA

75 participants

Immunotherapy Clearance and Phenotype of Circulating Tumor Cells in Lung and Head and Neck Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2021-10-27
Completion:: 2026-12-11

Conditions

Metastatic NSCLC
Metastatic Head and Neck Cancer

Interventions

OTHER

No Results Yet

NCT05084495 | COMPLETED

50 participants

The Use of Flecainide for Treatment of Atrial Fibrillation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-11
Start Date:: 2022-02-01
Completion:: 2025-04-15

Conditions

Atrial Fibrillation

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05054387 | COMPLETED | PHASE4

22 participants

China Post-marketing Surveillance (PMS) Study of Fabrazyme®

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2021-10-13
Completion:: 2023-03-09

Conditions

Fabry Disease

Interventions

DRUG

No Results Yet

NCT05049122 | COMPLETED | PHASE4

25 participants

Dupilumab in Japanese Patients With Chronic Rhinosinusitis With Nasal Polyp (SINUS-M52)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2021-10-22
Completion:: 2022-12-21

Conditions

Chronic Rhinosinusitis With Nasal Polyps

Interventions

DRUG

Results Available

NCT05043324 | COMPLETED | PHASE4

82 participants

Prevention and Treatment of Patient Before, During, and After Covid-19 Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2020-02-20
Completion:: 2022-04-20

Conditions

Covid19

Interventions

DRUG

No Results Yet

NCT05033041 | COMPLETED | PHASE4

72 participants

Gastric Volumes by US in Term Parturients Undergoing CS With and Without Metoclopramide

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2021-10-20
Completion:: 2024-01-30

Conditions

Pregnancy
Cesarean Section
Aspiration

Interventions

DRUG

Results Available

NCT05010265 | RECRUITING

70 participants

An Ethical Approach to Detecting Covert Consciousness

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-11
Start Date:: 2022-02-01
Completion:: 2027-07-31

Conditions

Disorder of Consciousness

Interventions

OTHER

No Results Yet

NCT04908787 | COMPLETED | PHASE3

421 participants

A Phase III Study of BD0801 Combined With Chemotherapy in Recurrent, Platinum-resistant Epithelial Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2021-06-11
Completion:: 2023-12-08

Conditions

Ovarian Cancer

Interventions

DRUG

No Results Yet

NCT04902573 | COMPLETED

147 participants

A Trial Monitoring Therapy Pathways of Asthma Patients Treated With an Extrafine ICS/LABA/LAMA Single-inhaler Triple Therapy in a Real-world Setting and Characterizing the Effects on Health-related Out-comes

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-11
Start Date:: 2021-06-17
Completion:: 2024-06-14

Conditions

Asthma

Interventions

OTHER

No Results Yet

NCT04870346 | ACTIVE_NOT_RECRUITING

36 participants

Long Term Follow-up Observational Study After Clinical Trials of AMG531 (Romiplostim) in Patients With Untreated Aplastic Anemia

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-11
Start Date:: 2021-05-10
Completion:: 2024-08-31

Conditions

Aplastic Anemia

No Results Yet

NCT04805528 | RECRUITING | NA

75 participants

Study of Non-invasive Acupuncture-like Transcutaneous Electrical Nerve Stimulation (Altens) to Help Alleviate Xerostomia After Radiation Therapy for Cancers of the Head and Neck

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2022-03-10
Completion:: 2028-05-31

Conditions

Head and Neck Cancer

Interventions

RADIATION

No Results Yet

NCT04802057 | TERMINATED | PHASE1

9 participants

Safety and Tolerability Study in Adults With Cold Agglutinin Disease Previously Treated With SAR445088 or Never Treated With SAR445088

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2021-03-22
Completion:: 2025-03-04

Conditions

Autoimmune Haemolytic Anaemia

Interventions

DRUG

No Results Yet

NCT04798027 | TERMINATED | PHASE1/PHASE2

182 participants

Study of mRNA Vaccine Formulation Against COVID-19 in Healthy Adults 18 Years of Age and Older

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2021-03-12
Completion:: 2022-06-27

Conditions

COVID-19

Interventions

BIOLOGICAL

Results Available

NCT04759131 | COMPLETED | PHASE3

74 participants

Safety, Efficacy and PK of BIVV001 in Pediatric Patients With Hemophilia A

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2021-02-19
Completion:: 2023-01-18

Conditions

Hemophilia A

Interventions

DRUG

Results Available

NCT04730609 | RECRUITING | PHASE4

40 participants

Dexmedetomidine for Intraoperative Shivering in Scheduled Elective Cesarean Delivery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2021-09-21
Completion:: 2026-08-31

Conditions

Shivering
Dose Finding Study

Interventions

DRUG

No Results Yet

NCT04715087 | COMPLETED | NA

7 participants

Staphylococcus Aureus in Atopic Dermatitis Immunopathology

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2022-10-26
Completion:: 2025-01-31

Conditions

Atopic Dermatitis

Interventions

OTHER

No Results Yet

NCT04657185 | COMPLETED

804 participants

Reducing Perioperative S. Aureus Transmission Via OR PathTrac

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-11
Start Date:: 2019-07-15
Completion:: 2020-03-20

Conditions

S. Aureus Transmission
Surgical Site Infection

Interventions

OTHER

No Results Yet

NCT04632108 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

199 participants

A 1/2 Phase Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of ASKB589 in Patients With Locally Advanced or Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-11
Start Date:: 2021-01-28
Completion:: 2025-10-31

Conditions

Malignant Solid Tumor

Interventions

DRUG

No Results Yet