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Combining HIIT and n-3 PUFA Supplementation to Reduce Inflammation and Improve Metabolic Health (HIIT&PUFA)

NCT05297383 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL

Last updated 2025-09-11

No results posted yet for this study

Summary

The goal of this pilot study is to understand the combined effects of fish oil and exercise in obesity-associated inflammation acutely. The investigators hypothesize that fish oil will improve gut bacteria profiles, which will in turn potentiate the benefits of an exercise program and reduce inflammation and metabolic risk.

Conditions

Interventions

DIETARY_SUPPLEMENT

Omega-3 Polyunsaturated Fatty Acid.

4 grams n-3 PUFA (AlaskOmega®) per day (3000 mg EPA and 1000 mg DHA).

DIETARY_SUPPLEMENT

Safflower Oil

4 grams safflower oil (AlaskOmega®) per day.

BEHAVIORAL

High-Intensity Interval Training

A 4 x 4 high-intensity interval training (HIIT) exercise program 3 days/week for 6 weeks. This will include a 3 min warm up at 15% watt max followed by 4 intervals for 4 min at 65% watt max with 3 min active recovery at 15% watt max.

BEHAVIORAL

Flexibility Training

30 min of stretching 3 days/week for 6 weeks

Sponsors & Collaborators

  • University of Houston

    collaborator OTHER

  • Texas Tech University Health Sciences Center

    collaborator OTHER

  • Texas Tech University

    lead OTHER

Principal Investigators

  • Kembra KA Albracht-Schulte, Ph.D. · Texas Tech University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
SEQUENTIAL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-04-01
Primary Completion
2022-06-01
Completion
2022-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05297383 on ClinicalTrials.gov