MedTrace Logo

Combining HIIT and n-3 PUFA to Reduce Inflammation and Improve Metabolic Health

NCT05295719 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 129

Last updated 2025-09-11

No results posted yet for this study

Summary

The goal of this project is to understand the combined effects of fish oil and exercise in obesity-associated inflammation. The investigators hypothesize that fish oil will improve gut bacteria profiles, which will in turn potentiate the benefits of an exercise program and improve energy utilization and reduce inflammation and metabolic risk.

Conditions

Interventions

DIETARY_SUPPLEMENT

Omega-3 polyunsaturated fatty acid

4 grams n-3 PUFA (AlaskOmega®) per day (3000 mg EPA and 1000 mg DHA)

BEHAVIORAL

High-Intensity Interval Training

A 4 x 4 high-intensity interval training (HIIT) exercise program 3 days/week for 4 weeks. This will include a 3 min warm up at 15% watt max followed by 4 intervals for 4 min at 65% watt max with 3 min active recovery at 15% watt max.

DIETARY_SUPPLEMENT

Safflower oil

4 grams safflower oil (AlaskOmega®) per day

BEHAVIORAL

Low-intensity training

A low-intensity training exercise program 3 days/week for 4 weeks. This will include consistently cycling at 50% HRmax for 30 min.

Sponsors & Collaborators

  • University of Houston

    collaborator OTHER

  • Texas Tech University Health Sciences Center

    collaborator OTHER

  • Texas Tech University

    lead OTHER

Principal Investigators

  • Kembra D Albracht-Schulte, Ph.D · Texas Tech University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
SEQUENTIAL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-09-01
Primary Completion
2024-12-31
Completion
2024-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05295719 on ClinicalTrials.gov