Clinical Trials

NCT04754542 | COMPLETED

76 participants

Discontinuation of Disease Modifying Therapies (DMTs) in Multiple Sclerosis (MS): Extension of the DISCOMS Study

Study Type:

OBSERVATIONAL

Last Updated:

2024-09-25

Start Date:

2021-05-18

Completion:

2022-11-30

Conditions

• Multiple Sclerosis

Results Available

NCT04721197 | RECRUITING | NA

400 participants

Hens Hatching Hope

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2021-01-23

Completion:

2026-01-22

Conditions

• Malnutrition, Child

Interventions

• OTHER

No Results Yet

NCT04672460 | COMPLETED | PHASE1

73 participants

A Bioequivalence Study Between the Proposed and Current Talazoparib Capsule Formulation and Food Effect Study for the Proposed Talazoparib Capsule Formulation in Participants With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2020-12-21

Completion:

2022-02-04

Conditions

• Advanced Solid Tumors
• Solid Tumors
• Ovarian Cancer
• Breast Cancer
• Prostate Cancer
• NSCLC
• Pancreatic Cancer
• Colorectal Cancer

Interventions

• DRUG

Results Available

NCT04644861 | COMPLETED | NA

37 participants

Adapted Physical Activity Centre (in The) CITY for Elders Aged 70 and Over with At Least One Long Term Illness

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2020-12-14

Completion:

2023-02-21

Conditions

• Chronic Disease

Interventions

• OTHER

No Results Yet

NCT04643327 | RECRUITING | PHASE2

28 participants

Uncovering a Novel Therapeutic Target to Reduce Dementia Risk in Parkinson's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2021-02-09

Completion:

2025-01-31

Conditions

• Parkinson Disease
• Mild Cognitive Impairment
• Memory Impairment

Interventions

• DRUG

No Results Yet

NCT04635878 | COMPLETED

11 participants

INFLAmmasomes NLRP3 in Platelets and Leukocytes During SEPSIS in Intensive Care Unit

Study Type:

OBSERVATIONAL

Last Updated:

2024-09-25

Start Date:

2020-07-27

Completion:

2023-05-30

Conditions

• Sepsis

Interventions

• OTHER

No Results Yet

NCT04619368 | COMPLETED

52 participants

Post-intensive Care Follow-up of Patients Hospitalized for an Acute Respiratory Distress Syndrome Caused by COVID-19

Study Type:

OBSERVATIONAL

Last Updated:

2024-09-25

Start Date:

2020-07-27

Completion:

2021-12-31

Conditions

• Human ARDS
• Coronavirus Infection

Interventions

• OTHER

No Results Yet

NCT04570709 | COMPLETED | NA

67 participants

RN-Led Palliative and Supportive Care Intervention

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2020-09-14

Completion:

2023-04-04

Conditions

• Acute Myeloid Leukemia

Interventions

• OTHER

Results Available

NCT04437914 | RECRUITING

110 participants

Accuracy of Cardiac Arrhythmias and Conduction Disorders Diagnosis Using a Smartwatch

Study Type:

OBSERVATIONAL

Last Updated:

2024-09-25

Start Date:

2021-06-07

Completion:

2024-08-30

Conditions

• Cardiovascular Diseases
• Cardiac Arrhythmia
• Conduction Disturbance

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04399369 | COMPLETED | PHASE2

688 participants

Preventing Caries with Silver Diamine Fluoride

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2020-10-22

Completion:

2023-10-11

Conditions

• Dental Caries

Interventions

• DEVICE

No Results Yet

NCT04398459 | ACTIVE_NOT_RECRUITING | PHASE2

18 participants

The Safety and Efficacy of Ibrutinib in Refractory/Relapsed Autoimmune Hemolytic Anemia

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2020-05-01

Completion:

2024-12-31

Conditions

• Refractory/Relapsed Autoimmune Hemolytic Anemia

Interventions

• DRUG

No Results Yet

NCT04387461 | COMPLETED | PHASE2

35 participants

Study of CG0070 Given in Combination With Pembrolizumab, in Non-Muscle Invasive Bladder Cancer, Unresponsive to Bacillus Calmette-Guerin

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2020-12-08

Completion:

2023-03-07

Conditions

• Non Muscle Invasive Bladder Cancer

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT04359056 | COMPLETED | NA

138 participants

Clinical Pharmacy for Patients with a PICC Line

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2020-05-25

Completion:

2021-12-15

Conditions

• Catheter Complications

Interventions

• OTHER

No Results Yet

NCT04322084 | WITHDRAWN

0 participants

Continuous Ambulatory Monitoring to Predict Elevated Risk of Infection in Children With Lymphoblastic Leukemia Undergoing Induction Chemotherapy (CAMPER-ALL)

Study Type:

OBSERVATIONAL

Last Updated:

2024-09-25

Start Date:

2024-09-30

Completion:

2024-10-31

Conditions

• Acute Lymphoblastic Leukemia

Interventions

• OTHER

No Results Yet

NCT04318444 | TERMINATED | PHASE2/PHASE3

10 participants

Hydroxychloroquine Post Exposure Prophylaxis for Coronavirus Disease (COVID-19)

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2020-03-29

Completion:

2021-03-31

Conditions

• COVID-19
• Corona Virus Infection

Interventions

• DRUG

Results Available

NCT04307602 | ACTIVE_NOT_RECRUITING | NA

60 participants

Long-term Exercise Effects from Robotic Walking

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2019-05-01

Completion:

2025-06-30

Conditions

• Exercise
• Children
• Cerebral Palsy

Interventions

• OTHER

No Results Yet

NCT04282629 | RECRUITING | PHASE2

234 participants

Cerebral Hemodynamic Optimization by Milrinone to Prevent Delayed Cerebral Ischemia

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2021-07-25

Completion:

2025-07-31

Conditions

• Aneurysmal Subarachnoid Hemorrhage

Interventions

• DRUG
• OTHER

No Results Yet

NCT04265261 | COMPLETED | PHASE2

139 participants

A Study to Investigate the Efficacy and Safety of RG7774 in Patients With Diabetes Mellitus Type 1 or Type 2 With Treatment-Naive Diabetic Retinopathy

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2020-06-05

Completion:

2023-07-19

Conditions

• Diabetic Retinopathy

Interventions

• DRUG

Results Available

NCT04262193 | TERMINATED | PHASE2

37 participants

Dual-Orexin Antagonism As a Mechanism for Improving Sleep and Drug Abstinence in Opioid Use Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2021-02-01

Completion:

2024-07-30

Conditions

• Opioid-use Disorder
• Sleep

Interventions

• DRUG

No Results Yet

NCT04233242 | COMPLETED | NA

286 participants

Genotype-Informed Versus Empiric Management of VirEmia

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2020-03-03

Completion:

2023-03-15

Conditions

• HIV-1-infection

Interventions

• OTHER

No Results Yet

NCT04225013 | COMPLETED

150 participants

Early Diagnosis as Strategy in Reducing the Incidence of Contrast-induced Nephropathy

Study Type:

OBSERVATIONAL

Last Updated:

2024-09-25

Start Date:

2015-06-01

Completion:

2018-06-01

Conditions

• Kidney Injury
• Contrast-induced Nephropathy

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04207255 | COMPLETED | PHASE2

69 participants

Addition of Opaganib to Androgen Antagonists in Patients With mCRPC

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2020-03-27

Completion:

2023-08-31

Conditions

• Prostate Cancer

Interventions

• DRUG

Results Available

NCT04188288 | TERMINATED | NA

12 participants

Neurofeedback in Individuals With Substance Use Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2021-07-01

Completion:

2023-03-15

Conditions

• Opioid-Related Disorders

Interventions

• DEVICE

Results Available

NCT04156126 | COMPLETED

56 participants

Measuring Immune Tolerance to Predict Miscarriage or Failed Embryo Transfer

Study Type:

OBSERVATIONAL

Last Updated:

2024-09-25

Start Date:

2019-08-23

Completion:

2024-06-01

Conditions

• Infertility
• Pregnancy Loss
• Spontaneous Abortion

Interventions

• OTHER

No Results Yet

NCT04155424 | TERMINATED | PHASE2/PHASE3

5 participants

A Study of the Safety and Activity of Eculizumab in Pediatric Participants With Relapsing Neuromyelitis Optica Spectrum Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2020-01-14

Completion:

2023-07-31

Conditions

• Neuromyelitis Optica
• Neuromyelitis Optica Spectrum Disorder

Interventions

• DRUG

Results Available

NCT04094779 | COMPLETED | NA

28 participants

Effect of "breath of Fresh Air" Flash Activity on Dementia Agitation : Pilot Study

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2019-09-20

Completion:

2022-03-08

Conditions

• Dementia

Interventions

• OTHER

No Results Yet

NCT04061161 | COMPLETED | PHASE4

37 participants

Anti-inflammatory Effects of Tiotropium in Patients with Stable COPD

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2019-08-19

Completion:

2023-12-31

Conditions

• COPD

Interventions

• DRUG

No Results Yet

NCT03972384 | COMPLETED | NA

19 participants

A Problem Solving Intervention for Post-ICU Cognitive Impairment in Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2022-01-21

Completion:

2023-03-01

Conditions

• Critical Illness
• Mechanical Ventilation Complication
• Delirium
• Cognitive Impairment

Interventions

• BEHAVIORAL

No Results Yet

NCT03827694 | RECRUITING

400 participants

Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections

Study Type:

OBSERVATIONAL

Last Updated:

2024-09-25

Start Date:

2018-10-30

Completion:

2025-12-31

Conditions

• Pulmonary Invasive Fungal Infections
• Pulmonary Invasive Aspergillosis

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03751475 | COMPLETED | NA

896 participants

Optimizing Acute Malnutrition Management in Children Aged 6 to 59 Months in Democratic Republic of Congo

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2019-07-22

Completion:

2020-07-20

Conditions

• Severe Acute Malnutrition
• Moderate Acute Malnutrition
• Child Malnutrition
• Acute Malnutrition
• Congo, The Democratic Republic of the
• Africa
• Randomized Clinical Trial

Interventions

• OTHER

No Results Yet

NCT03581370 | RECRUITING | PHASE3

80 participants

Short Infusion Versus Prolonged Infusion of Ceftolozane-tazobactam Among Patients with Ventilator Associated-pneumonia

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2018-09-20

Completion:

2025-02-28

Conditions

• Ventilator-associated Pneumonia

Interventions

• DRUG

No Results Yet

NCT03565003 | COMPLETED | PHASE1/PHASE2

126 participants

A First-in-Human Study of JAB-3068 (SHP2 Inhibitor) in Adult Patients With Advanced Solid Tumors in China

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2018-11-20

Completion:

2023-01-31

Conditions

• Non-small Cell Lung Cancer
• Head and Neck Cancer
• Esophageal Cancer
• Other Metastatic Solid Tumors

Interventions

• DRUG

No Results Yet

NCT03484182 | COMPLETED | NA

58 participants

Efficacy of an Interactive Web-Based Home Therapy Program After Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2019-09-01

Completion:

2022-06-22

Conditions

• Stroke

Interventions

• BEHAVIORAL

No Results Yet

NCT03420430 | NO_LONGER_AVAILABLE

Expanded Access to Provide GL-ONC1 for the Treatment of Advanced Cancers With No Standard of Care

Study Type:

EXPANDED_ACCESS

Last Updated:

2024-09-25

Conditions

• Advanced Stage Cancer (Solid Tumor Disease for 4 Patients)
• Acute Myeloid Leukemia (6 Patients)

Interventions

• BIOLOGICAL

No Results Yet

NCT03418779 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

60 participants

Treatment Effects of Chinese Medicine (Yi-Qi-Qing-Jie Herbal Compound) Combined With Immunosuppression Therapies in IgA Nephropathy Patients With High-risk of ESRD

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2019-07-04

Completion:

2024-09-25

Conditions

• IgA Nephropathy at High Risk of Developing ESRD

Interventions

• DRUG
• OTHER

No Results Yet

NCT03332966 | RECRUITING

1000 participants

Youth Experiences and Health Study

Study Type:

OBSERVATIONAL

Last Updated:

2024-09-25

Start Date:

2019-12-01

Completion:

2024-12-31

Conditions

• Psychotic Disorders
• Psychiatric Hospitalization
• Prodromal Symptoms
• Cannabis Use
• Trauma, Psychological

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03251378 | COMPLETED | PHASE1

129 participants

A Multi-Center, Open-Label Study of Fruquintinib in Solid Tumors and Colorectal, and Breast Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2017-12-11

Completion:

2022-12-13

Conditions

• Advanced Solid Tumors
• Metastatic Colon Cancer
• Metastatic Breast Cancer
• Triple Negative Breast Cancer
• HER2-negative Breast Cancer
• Hormone Receptor Positive Breast Carcinoma
• Rectal Cancer

Interventions

• DRUG

Results Available

NCT03205475 | COMPLETED | NA

27 participants

JASPER Implementation in NFLD

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2018-05-01

Completion:

2018-12-31

Conditions

• Autism Spectrum Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT03153241 | COMPLETED

100 participants

Subglottic Secretion Culture in Predicting Tracheal Microbial Flora

Study Type:

OBSERVATIONAL

Last Updated:

2024-09-25

Start Date:

2017-10-20

Completion:

2018-10-20

Conditions

• Pneumonia

Interventions

• OTHER

No Results Yet

NCT03131726 | RECRUITING | PHASE3

80 participants

Treatment of Graves´ophthalmopathy with Simvastatin (GO-S)

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-25

Start Date:

2018-01-26

Completion:

2027-01-26

Conditions

• Graves Ophthalmopathy
• Thyroid Associated Ophthalmopathy
• Thyroid Associated Orbitopathy

Interventions

• DRUG

No Results Yet