Measuring Immune Tolerance to Predict Miscarriage or Failed Embryo Transfer
NCT04156126 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 56
Last updated 2024-09-25
Summary
Pregnancy is a unique period which requires alterations in the immune system to allow for tolerance of a haploidentical fetus. The goal of this study is to measure maternal blood levels of proteins known to promote immune tolerance in early implantation and pregnancy to look for associations between tolerance, miscarriage and failed embryo transfer. Establishing predictive factors of miscarriage and failed in vitro fertilization could have implications for a large portion of couples and serve to guide current and future family planning efforts.
Conditions
- Infertility
- Pregnancy Loss
- Spontaneous Abortion
Interventions
- OTHER
-
Blood Collection
Blood Collection
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Chandra C Shenoy, M.D. · Mayo Clinic
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-08-23
- Primary Completion
- 2024-06-01
- Completion
- 2024-06-01
Countries
- United States
Study Locations
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