Measuring Immune Tolerance to Predict Miscarriage or Failed Embryo Transfer

NCT04156126 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 56

Last updated 2024-09-25

No results posted yet for this study

Summary

Pregnancy is a unique period which requires alterations in the immune system to allow for tolerance of a haploidentical fetus. The goal of this study is to measure maternal blood levels of proteins known to promote immune tolerance in early implantation and pregnancy to look for associations between tolerance, miscarriage and failed embryo transfer. Establishing predictive factors of miscarriage and failed in vitro fertilization could have implications for a large portion of couples and serve to guide current and future family planning efforts.

Conditions

Interventions

OTHER

Blood Collection

Blood Collection

Sponsors & Collaborators

Principal Investigators

  • Chandra C Shenoy, M.D. · Mayo Clinic

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-08-23
Primary Completion
2024-06-01
Completion
2024-06-01

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04156126 on ClinicalTrials.gov