Clinical Trials

NCT04619251 | COMPLETED | PHASE1

74 participants

A Study in Healthy Japanese Men to Test How Different Doses of BI 1323495 Are Tolerated and How Itraconazole Influences the Amount of BI 1323495 in the Blood

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2020-11-13

Completion:

2021-07-30

Conditions

• Healthy

Interventions

• DRUG

Results Available

NCT04614428 | COMPLETED | NA

203 participants

Improving Outcomes in Patients With Cardiovascular Seasonality

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2020-11-25

Completion:

2023-07-28

Conditions

• Cardiovascular Diseases

Interventions

• BEHAVIORAL

No Results Yet

NCT04613674 | COMPLETED | PHASE3

441 participants

A Study of Camrelizumab Plus Chemotherapy vs Placebo Plus Chemotherapy as Neoadjuvant Therapy in Participants With Triple Negative Breast Cancer (TNBC)

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2020-12-09

Completion:

2023-09-14

Conditions

• Triple Negative Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04592341 | TERMINATED | PHASE2

192 participants

A Study to Evaluate the Pharmacodynamic (PD) Effects of Once Weekly Administration of Gantenerumab in Participants With Early Alzheimer's Disease (AD)

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2020-11-18

Completion:

2023-01-11

Conditions

• Alzheimer Disease

Interventions

• DRUG

Results Available

NCT04389970 | COMPLETED | NA

12 participants

Time Restricted Eating Outcomes in Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2020-10-01

Completion:

2021-07-30

Conditions

• Multiple Sclerosis
• Diet, Healthy

Interventions

• BEHAVIORAL

Results Available

NCT04381260 | COMPLETED

473 participants

RUral dispaRities in prehospitAL STEMI

Study Type:

OBSERVATIONAL

Last Updated:

2024-03-27

Start Date:

2020-12-15

Completion:

2022-06-02

Conditions

• ST Elevation Myocardial Infarction
• Cardiovascular Diseases

Interventions

• OTHER

No Results Yet

NCT04377672 | COMPLETED | PHASE1

14 participants

Human Convalescent Plasma for High Risk Children Exposed or Infected With SARS-CoV-2 (COVID-19)

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2020-05-28

Completion:

2021-09-01

Conditions

• SARS-CoV-2 Infection

Interventions

• BIOLOGICAL

Results Available

NCT04337749 | WITHDRAWN | PHASE4

0 participants

Chlorhexidine Scrub, ZnO Nanoparticles Socks and the Combination for Prevention of Pitted Keratolysis

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2022-11-05

Completion:

2022-12-01

Conditions

• Foot Dermatoses

Interventions

• DRUG
• DEVICE
• COMBINATION_PRODUCT

No Results Yet

NCT04177108 | COMPLETED | PHASE3

242 participants

A Study of Ipatasertib in Combination With Atezolizumab and Paclitaxel as a Treatment for Participants With Locally Advanced or Metastatic Triple-Negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2019-11-25

Completion:

2023-02-28

Conditions

• Triple-Negative Breast Cancer

Interventions

• DRUG

Results Available

NCT04167813 | ACTIVE_NOT_RECRUITING | PHASE2

168 participants

Trial of Ondansetron as a Parkinson's HAllucinations Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2021-10-01

Completion:

2024-08-30

Conditions

• Parkinson's Hallucinations
• Dementia With Lewy Bodies

Interventions

• DRUG

No Results Yet

NCT04139564 | COMPLETED | NA

108 participants

EaseVRx for the Reduction of Chronic Pain and Opioid Use

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2021-01-11

Completion:

2022-08-31

Conditions

• Chronic Low-back Pain

Interventions

• DEVICE

Results Available

NCT04114890 | COMPLETED | PHASE2

27 participants

Tenofovir in Pregnancy to Prevent Mother to Child Transmission of Hepatitis B.

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2021-01-08

Completion:

2023-09-29

Conditions

• Hepatitis B
• Tenofovir
• Pregnancy

Interventions

• DRUG

No Results Yet

NCT04110054 | COMPLETED | PHASE2

406 participants

Evaluation of S-600918 in Adults With Refractory Chronic Cough

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2020-02-13

Completion:

2020-12-08

Conditions

• Chronic Cough

Interventions

• DRUG

Results Available

NCT04103554 | ACTIVE_NOT_RECRUITING | PHASE4

60 participants

Sacubitril/Valsartan in Left Ventricular Assist Device Recipients

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2021-02-05

Completion:

2025-02-28

Conditions

• Heart Failure

Interventions

• DRUG

No Results Yet

NCT04093765 | COMPLETED | NA

5542 participants

Mass Screening and Treatment for Reduction of Falciparum Malaria

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2018-11-01

Completion:

2019-12-31

Conditions

• Plasmodium Falciparum Malaria

Interventions

• DIAGNOSTIC_TEST
• DRUG

No Results Yet

NCT04074317 | COMPLETED | PHASE2

18 participants

Phase 2, Randomized, Open-Label, Crossover, PD/PK Study of a Novel Pram-Insulin Co-Formulation in Adults With T1D

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2019-08-22

Completion:

2020-04-02

Conditions

• Diabetes Mellitus, Type 1
• Insulin-dependent Diabetes Mellitus

Interventions

• DRUG

Results Available

NCT04070105 | COMPLETED | NA

6 participants

No Power Bionic Lower Extremity Prosthesis

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2020-09-01

Completion:

2022-12-31

Conditions

• Amputation
• Amputation, Traumatic
• Amputation; Traumatic, Leg, Lower

Interventions

• DEVICE

Results Available

NCT04059562 | COMPLETED | PHASE2

28 participants

Trifluridine/Tipiracil in Combination With Irinotecan as a Second Line Therapy in Patients With Cholangiocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2021-10-28

Completion:

2024-01-08

Conditions

• Cholangiocarcinoma

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT04024397 | COMPLETED

1796 participants

A Study to Evaluate Unintended Prolonged Opioid Use

Study Type:

OBSERVATIONAL

Last Updated:

2024-03-27

Start Date:

2019-10-01

Completion:

2023-12-01

Conditions

• Opioid Use

No Results Yet

NCT04021706 | COMPLETED | PHASE1

32 participants

Effect of a Ghrelin Receptor Agonist on Muscle and Bone

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2019-12-05

Completion:

2023-01-26

Conditions

• Sarcopenia
• Osteopenia

Interventions

• DRUG

Results Available

NCT04012164 | COMPLETED | NA

60 participants

Viral and Microbial Circulation Between Humans, Domesticated and Wild Animals Along an Ecotone, Democratic Republic of Congo

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2019-03-15

Completion:

2021-09-21

Conditions

• Zoonotic Disease

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT03991936 | COMPLETED | PHASE4

11 participants

Benefit of Placebo and Different Concentrations of Triamcinolone Acetonide in Nail Psoriasis

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2020-03-11

Completion:

2023-03-29

Conditions

• Nail Psoriasis
• Nail Diseases

Interventions

• DRUG

Results Available

NCT03980483 | COMPLETED | PHASE3

1537 participants

Efficacy and Safety of GSK3196165 Versus Placebo and Tofacitinib in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2019-05-16

Completion:

2021-09-15

Conditions

• Arthritis, Rheumatoid

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT03972709 | TERMINATED | PHASE2

372 participants

A Study Assessing the Safety, Tolerability, and Efficacy of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (AMD)

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2019-06-03

Completion:

2022-10-27

Conditions

• Macular Degeneration, Age-Related
• Geographic Atrophy

Interventions

• DRUG

Results Available

NCT03932253 | SUSPENDED | PHASE1

79 participants

MEK Inhibitor FCN-159 To Treat Advanced Melanoma With NRAS-aberrant (Ia) and NRAS-mutant (Ib)or NF1-mutant(1b)

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2019-03-21

Completion:

2023-04-30

Conditions

• Melanoma

Interventions

• OTHER

No Results Yet

NCT03895775 | RECRUITING

740 participants

Prevalence of Sleep Apnoea in Adolescents

Study Type:

OBSERVATIONAL

Last Updated:

2024-03-27

Start Date:

2019-12-13

Completion:

2024-12-31

Conditions

• Obstructive Sleep Apnea

No Results Yet

NCT03847610 | COMPLETED | PHASE1

11 participants

Minimally Invasive Sensing of Beta-lactam Antibiotics

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2018-04-12

Completion:

2018-08-10

Conditions

• Healthy Volunteers

Interventions

• DRUG
• DEVICE

Results Available

NCT03727789 | TERMINATED | PHASE1

7 participants

CBL0137 in Treating Patients With Advanced Extremity Melanoma or Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2019-07-01

Completion:

2024-01-16

Conditions

• Advanced Cutaneous Melanoma of the Extremity
• Advanced Sarcoma of the Extremity
• Clinical Stage III Cutaneous Melanoma AJCC v8
• Clinical Stage IV Cutaneous Melanoma AJCC v8
• Pathologic Stage IIIB Cutaneous Melanoma AJCC v8
• Pathologic Stage IIIC Cutaneous Melanoma AJCC v8
• Pathologic Stage IV Cutaneous Melanoma AJCC v8
• Recurrent Cutaneous Melanoma of the Extremity
• Recurrent Sarcoma of the Extremity
• Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
• Stage IIIA Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
• Stage IIIB Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
• Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8

Interventions

• DRUG

No Results Yet

NCT03634488 | COMPLETED | PHASE2

132 participants

Management of Severe Acute Malnutrition in SCD, in Northern Nigeria

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2021-08-18

Completion:

2022-10-05

Conditions

• Sickle Cell Anemia
• Severe Acute Malnutrition

Interventions

• DRUG
• DIETARY_SUPPLEMENT

Results Available

NCT03605368 | COMPLETED | NA

158 participants

VR Intervention to Improve Police Safety

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2017-11-17

Completion:

2022-10-12

Conditions

• Autism Spectrum Disorder
• Autism

Interventions

• BEHAVIORAL

Results Available

NCT03559634 | COMPLETED | NA

55 participants

Contraception Initiation Feasibility in the Pediatric ED

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2019-05-20

Completion:

2021-01-26

Conditions

• Contraception
• Contraception Behavior

Interventions

• DIAGNOSTIC_TEST
• OTHER

No Results Yet

NCT03556618 | TERMINATED | NA

19 participants

A Pilot Trial of a Network Intervention for Youth After Incarceration

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2020-03-02

Completion:

2021-12-16

Conditions

• Youth Incarceration
• Health Care Utilization

Interventions

• BEHAVIORAL

Results Available

NCT03457701 | COMPLETED | PHASE2

15 participants

Anemia Studies in CKD: Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat- Iron (ASCEND: Fe)

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2019-07-30

Completion:

2022-07-05

Conditions

• Anaemia

Interventions

• DRUG

Results Available

NCT03446612 | TERMINATED | PHASE2

6 participants

Anemia Study in Chronic Kidney Disease (CKD) : Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat -Forearm Blood Flow (ASCEND-FBF)

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2019-01-10

Completion:

2019-05-29

Conditions

• Anaemia

Interventions

• DRUG

Results Available

NCT03433924 | COMPLETED

248 participants

An Epidemiologic Study on PD-L1 Expression Combined With Clinical Observation in the Chinese MIUBC Patients.

Study Type:

OBSERVATIONAL

Last Updated:

2024-03-27

Start Date:

2020-05-18

Completion:

2023-03-27

Conditions

• Urinary Bladder Cancer

No Results Yet

NCT03433781 | COMPLETED | PHASE1/PHASE2

4 participants

A Phase Ib Study Evaluating the Safety and Tolerability of Vitamin C in Patients With Intermediate or High Risk Myelodysplastic Syndrome With TET2 Mutations

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2018-05-01

Completion:

2022-11-06

Conditions

• Myelodysplastic Syndromes

Interventions

• DRUG

Results Available

NCT03400410 | COMPLETED | NA

107 participants

Hormonal Contraceptive Health Education for Adolescent Males

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2018-05-21

Completion:

2020-03-18

Conditions

• Contraception Behavior

Interventions

• BEHAVIORAL

No Results Yet

NCT03377660 | TERMINATED

30 participants

Resection of the Esophagus and Subsequent Weight Loss

Study Type:

OBSERVATIONAL

Last Updated:

2024-03-27

Start Date:

2018-01-01

Completion:

2023-03-01

Conditions

• Esophageal Cancer
• Weight Gain
• Eating Behavior
• Food Reward

Interventions

• OTHER

No Results Yet

NCT03353220 | TERMINATED | PHASE4

32 participants

Predictors of Lorcaserin-Induced Weight Loss

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2018-01-03

Completion:

2020-02-14

Conditions

• Overweight and Obesity

Interventions

• DRUG

Results Available

NCT03321630 | COMPLETED | PHASE2

24 participants

A Phase II a Study of Lenvatinib, a Multi-targeted Tyrosine Kinase Inhibitor, Combined With Pembrolizumab (PD-1 Inhibitor) for the Treatment of Metastatic Gastroesophageal Cancer Patients Who Have Progressed on First or Subsequent Line Therapies

Study Type:

INTERVENTIONAL

Last Updated:

2024-03-27

Start Date:

2017-10-24

Completion:

2023-03-10

Conditions

• GastroEsophageal Cancer
• Gastric Cancer

Interventions

• DRUG

Results Available