Clinical Trials Updated in 2021

NCT04872244 | COMPLETED | NA

30 participants

Can Intrauterine Levonorgestrel Releasing Device Be a Treatment Option for Postmenstrual Spotting in Isthmocele

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2019-11-03
Completion:: 2021-06-03

Conditions

Isthmocele
Post-menstrual Spotting Bleeding
Pelvic Pain

Interventions

DEVICE
DRUG

No Results Yet

NCT04869800 | COMPLETED | PHASE1

32 participants

Evaluate the Drug-drugs Interaction Between Lobeglitazone 0.5mg and Empagliflozin 25mg

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2021-05-27
Completion:: 2021-06-07

Conditions

Type 2 Diabetes Mellitus

Interventions

DRUG

No Results Yet

NCT04853680 | UNKNOWN | NA

80 participants

Effect of Anti-adhesion Barrier on the Voice Quality After Thyroidectomy.

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2021-07-01
Completion:: 2023-06-30

Conditions

Thyroid Nodule
Thyroid Cancer
Voice Disorders

Interventions

DEVICE

No Results Yet

NCT04830904 | UNKNOWN | NA

30 participants

Efficacy of Lycra Garments in Ataxic Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-08-03
Completion:: 2022-12-31

Conditions

Ataxia, Cerebellar

Interventions

DEVICE

No Results Yet

NCT04816838 | RECRUITING | NA

25 participants

A Window of Opportunity Study for Investigating Drug Tolerant Persister (DTP) to Neoadjuvant Osimertinib in Resectable Non-small Cell Lung Cancer (NSCLC) Harbouring EGFR Mutations

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2021-05-10
Completion:: 2025-07-31

Conditions

Non Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT04771390 | COMPLETED | PHASE1

52 participants

Study to Compare How the Body Absorbs, Distributes and Excretes the Drug Selitrectinib (BAY2731954) Given as Two Different Tablet Formulations or as Liquid Formulations Including the Effect of Food on the Absorption, Distribution or Excretion of the Different Formulations in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2021-02-16
Completion:: 2021-05-20

Conditions

Solid Tumors Harboring NTRK Fusion

Interventions

DRUG

No Results Yet

NCT04759534 | UNKNOWN | PHASE3

20 participants

Application of PCSK9 Inhibitors in Patients With Heterozygous Familial Hypercholesterolemia

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-09-10
Completion:: 2021-10-30

Conditions

Efficacy and Safety
Heterozygous Familial Hypercholesterolemia
PCSK9

Interventions

BIOLOGICAL

No Results Yet

NCT04758169 | UNKNOWN | NA

1200 participants

Exploring Enhanced HFP to Reduce Child Marriage in Bangladesh

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2021-02-01
Completion:: 2021-03-30

Conditions

Adolescent Behavior
Health Behavior
Marriage Age

Interventions

OTHER

No Results Yet

NCT04753151 | UNKNOWN | NA

140 participants

The Effects of Tranexamic Acid or Placebo on Perioperative Bleeding in Adults Undergoing Liver Transplantation.

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2021-08-11
Completion:: 2022-12-31

Conditions

Hemorrhage

Interventions

DRUG

No Results Yet

NCT04738435 | COMPLETED

600 participants

Safety of the Sputnik V Vaccine in Health Personnel of Private Effectors of the City of Buenos Aires, Argentina

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-25
Start Date:: 2021-01-05
Completion:: 2021-03-01

Conditions

COVID-19

No Results Yet

NCT04680416 | WITHDRAWN

0 participants

Tissue Collection to ID TCRs From Renal Clear Cell Carcinoma Patients Responding to Immune Checkpoint Inhibitors

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-12-17
Completion:: 2021-08-04

Conditions

Renal Clear Cell Carcinoma

No Results Yet

NCT04673279 | COMPLETED

189 participants

Long-term COVID-19 Immune Response in a Vulnerable Neighbourhood in Argentina

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-12-02
Completion:: 2021-08-20

Conditions

Coronavirus Disease 2019

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04667273 | COMPLETED | NA

48 participants

Effectiveness of Neuromuscular Electrical Stimulation in Patients With Subacromial Impingement Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-12-20
Completion:: 2021-03-23

Conditions

Subacromial Impingement Syndrome

Interventions

PROCEDURE

No Results Yet

NCT04637347 | COMPLETED | NA

110 participants

SC vs IC Approach for US-guided SC Vein Catheterization

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-12-01
Completion:: 2021-05-31

Conditions

Central Venous Catheter

Interventions

DEVICE

No Results Yet

NCT04636606 | COMPLETED | NA

60 participants

Efficacy of the Myofunctional Therapy on Oral Dysphagia

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-12-01
Completion:: 2021-06-25

Conditions

Dysphagia, Oral Phase
Temporomandibular Disorders

Interventions

PROCEDURE

No Results Yet

NCT04625595 | COMPLETED | PHASE1

30 participants

Multiple Ascending Dose (MAD) Study of IMT-002 in HLA-DQ8-positive Type 1 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-11-09
Completion:: 2021-05-11

Conditions

Type1 Diabetes

Interventions

DRUG

No Results Yet

NCT04617470 | UNKNOWN

300 participants

Niraparib as Maintenance Treatment in Platinum Responsive Ovarian Cancer Patients: a Real Life Study

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-07-08
Completion:: 2022-01-01

Conditions

Ovarian Cancer

No Results Yet

NCT04598607 | COMPLETED | PHASE1

36 participants

Tolerability and Pharmacokinetics of Hypidone Hydrochloride in Healthy Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-10-30
Completion:: 2021-01-11

Conditions

Major Depressive Disorder

Interventions

DRUG

No Results Yet

NCT04590638 | COMPLETED | NA

56 participants

Comparison Between Effect of Adrenaline and Without Adrenaline in Tumescent Solutions on Bleeding Control of Skin Graft Donor Site.

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-10-17
Completion:: 2021-03-17

Conditions

Bleeding Time

Interventions

OTHER

No Results Yet

NCT04568876 | COMPLETED | PHASE4

40 participants

Micronized and Ultramicronized Palmitoylethanolamide in COVID-19 Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-10-23
Completion:: 2021-02-28

Conditions

Covid19

Interventions

DIETARY_SUPPLEMENT
COMBINATION_PRODUCT

No Results Yet

NCT04534439 | COMPLETED | PHASE2

140 participants

Safety, Tolerability and Renal Effects of APX-115 in Subjects With Type 2 Diabetes and Nephropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-08-24
Completion:: 2021-07-26

Conditions

Diabetic Nephropathies
Diabetes Mellitus, Type 2
Nephropathy, Diabetic

Interventions

DRUG

No Results Yet

NCT04528602 | COMPLETED | NA

60 participants

The Effect of Diaper Change Position on Preterm Infants

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2019-05-17
Completion:: 2020-05-01

Conditions

Infant, Premature, Diseases

Interventions

PROCEDURE

No Results Yet

NCT04514835 | UNKNOWN | PHASE2

44 participants

A Phase Ⅱ Trials of Sintilimab as Consolidation Therapy After Radical Concurrent Chemoradiotherapy in Locally Advanced Unresectable ESCC

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2021-12-01
Completion:: 2022-01-31

Conditions

Esophageal Squamous Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT04511169 | COMPLETED | NA

100 participants

MyADHD-digital Training for Adults With ADHD

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-05-20
Completion:: 2021-02-20

Conditions

ADHD - Combined Type

Interventions

BEHAVIORAL

No Results Yet

NCT04503876 | UNKNOWN | NA

45 participants

Effects of End-expiratory Positive Pressure Optimization in Intubated Patients With Healthy Lung or Acute Respiratory Distress Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2019-09-12
Completion:: 2021-09-12

Conditions

ICU Patients
Healthy Lung
Positive End-Expiratory Pressure
ARDS
Alveolar Recruitment Maneuver

Interventions

OTHER

No Results Yet

NCT04492813 | COMPLETED | NA

40 participants

Plasmatic Concentrations of Propofol and Remifentanil in Obese and Non Obese Patients.

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2018-12-20
Completion:: 2021-01-25

Conditions

General Anesthesia
Obesity

Interventions

DRUG

No Results Yet

NCT04482842 | WITHDRAWN | NA

0 participants

Gene-guided Warfarin for Anticoagulation Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-12-10
Completion:: 2021-08-20

Conditions

Stroke

Interventions

DEVICE
DRUG

No Results Yet

NCT04475068 | COMPLETED

15 participants

Postural Recruitment Maneuver in Patients With Acute Respiratory Distress Syndrome Due to COVID-19 Infection

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-07-17
Completion:: 2020-09-30

Conditions

Sars-CoV2
ARDS

Interventions

PROCEDURE

No Results Yet

NCT04468009 | COMPLETED | PHASE2

134 participants

Treatment of Critically Ill Patients With Covid-19 With Convalescent Plasma

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-06-25
Completion:: 2021-01-19

Conditions

SARS-Associated Coronavirus
Covid19
SARS-CoV Infection

Interventions

BIOLOGICAL

No Results Yet

NCT04455217 | COMPLETED

350 participants

Long--term Outcome Analysis of Fracture--related Infections

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-02-13
Completion:: 2021-02-28

Conditions

Fracture-associated Infection (FAI)

Interventions

OTHER

No Results Yet

NCT04437472 | COMPLETED

30 participants

Remote Collection of Patient Reported Toxicity Using SMS Text Messaging (CareSignal)

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-09-22
Completion:: 2021-07-09

Conditions

Cancer

Interventions

OTHER

No Results Yet

NCT04433481 | UNKNOWN | NA

84 participants

Efficacy and Safety of Dabigatran in Patients With Cirrhosis and Portal Vein Thrombosis

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-06-20
Completion:: 2022-05-31

Conditions

Liver Cirrhosis
Portal Vein Thrombosis

Interventions

DRUG
OTHER

No Results Yet

NCT04414436 | UNKNOWN | NA

100 participants

A Guided Internet Intervention for Women Treated for Gynecological Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2021-02-25
Completion:: 2021-12-01

Conditions

Quality of Life

Interventions

BEHAVIORAL

No Results Yet

NCT04400552 | COMPLETED | NA

91 participants

Perioperative Oral Nutrition Supplementation in Malnourished Surgical Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2018-12-26
Completion:: 2021-06-30

Conditions

Cancer of Breast
Cancer Colon

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT04399278 | COMPLETED | NA

40 participants

End-eXpiratory Occlusion Test to Predict fluId REsponsiveness in the Operating Room (EXPIRE)

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-08-03
Completion:: 2021-03-24

Conditions

Hemodynamic Instability
General Anesthesia
Surgery
Protective Mechanical Ventilation

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04395950 | WITHDRAWN | PHASE1

0 participants

Effects of ACC Inhibitor on Lipid and Lipoprotein Metabolism

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-12-31
Completion:: 2021-08-19

Conditions

NASH (Nonalcoholic Steatohepatitis)
NAFLD (Nonalcoholic Fatty Liver Disease)

Interventions

DRUG

No Results Yet

NCT04385719 | COMPLETED | PHASE2

24 participants

Drug-drug Interactions Between Remdesivir and Commonly Used Antiretroviral Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2021-05-05
Completion:: 2021-07-02

Conditions

Ebola
HIV/AIDS

Interventions

DRUG

No Results Yet

NCT04375566 | UNKNOWN

45 participants

Progressive Web App About Individualized Patient Decision Aid for NSCLC Stage I-II

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-25
Start Date:: 2021-10-04
Completion:: 2022-01-31

Conditions

Lung Cancer Stage I
Lung Cancer Stage II

Interventions

OTHER

No Results Yet

NCT04302116 | RECRUITING | NA

250 participants

Vigabatrin With High Dose Prednisolone Combination Therapy vs Vigabatrin Alone for Infantile Spasm

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2020-05-18
Completion:: 2026-06-30

Conditions

Infantile Spasm
West Syndrome

Interventions

DRUG

No Results Yet

NCT04288934 | COMPLETED | PHASE1

20 participants

Treatment of Spinal Cord Injuries With (AutoBM-MSCs)vs (WJ-MSCs).

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-25
Start Date:: 2017-08-15
Completion:: 2020-04-15

Conditions

Spinal Cord Injuries

Interventions

BIOLOGICAL
DIAGNOSTIC_TEST

No Results Yet