MedTrace Logo

Postural Recruitment Maneuver in Patients With Acute Respiratory Distress Syndrome Due to COVID-19 Infection

NCT04475068 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 15

Last updated 2021-08-25

No results posted yet for this study

Summary

The purpose of this study is to evaluate if a postural recruitment maneuver (PRM) improves the aeration and distribution of lung ventilation in patients with Acute Respiratory Distress Syndrome (ARDS) caused by COVID-19 infection; without the need to reach high airway pressures as in the standard lung recruitment maneuver and / or place the patient in prone position. This strategy could be particularly useful in the context of a major health emergency in centers with limited resources.

Conditions

  • Sars-CoV2
  • ARDS

Interventions

PROCEDURE

Lateral Position (left and right lateral decubitus)

Prior to initiating the protocol, patients will be sedated deeply with sedatives and opioids and paralyzed. Patients will be evaluated in 5 positions sequentially: 1) Supine 2) Left lateral 3) Supine 4) Right lateral 5) Supine. The side with the least ventilation evaluated by EIT will define which side will start the sequence. Each step will last 30 minutes. Aeration measured by Electric Impedance Tomography (EIT) and lung ultrasound, distribution of the lung ventilation and perfusion measured by EIT, ventilator and hemodynamic parameters, esophageal pressure, and blood gas analysis will be recorded at the end of each step. Continuous monitoring of blood pressure, heart rate and saturation of arterial blood (SpO2) will be carried out during all steps of the protocol to assess the tolerance to the procedure.

Sponsors & Collaborators

  • Universidad de Piura

    collaborator UNKNOWN

  • Hospital Nacional Edgardo Rebagliati Martins

    lead OTHER

Principal Investigators

  • Rollin Roldán, MD · Hospital Nacional Edgardo Rebagliati Martins

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-07-17
Primary Completion
2020-09-30
Completion
2020-10-31

Countries

  • Peru

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04475068 on ClinicalTrials.gov