Long-term COVID-19 Immune Response in a Vulnerable Neighbourhood in Argentina

NCT04673279 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 189

Last updated 2021-08-25

No results posted yet for this study

Summary

Between June 10t h and July 1st, a cross-sectional design study in an Argentina slum, showed a prevalence based on immunoglobuling G-class (IgG) antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) of 53.4%. It remains unanswered whether natural infection produces sustained antibodies. The aim of this study is to evaluate the presence of IgG antibodies for Coronavirus disease 2019 (COVID-19) after 5 months in inhabitants of Barrio 31 who consented the Seroprevalence Study for COVID-19.

Conditions

  • Coronavirus Disease 2019

Interventions

DIAGNOSTIC_TEST

serology

An enzyme linked immunosorbent assay (ELISA) developed and validated in Argentina which detects antibodies against two viral antigens, trimeric spike and the receptor binding domain (RBD) of the spike protein.

Sponsors & Collaborators

  • Hospital de Niños R. Gutierrez de Buenos Aires

    collaborator OTHER
  • Ministerio de Salud GCBA

    collaborator UNKNOWN
  • Hospital Italiano de Buenos Aires

    lead OTHER

Principal Investigators

  • Vanina Pagotto, MD MG · Hospital Italiano de Buenos Aires

  • Alicia Mistchenko, Phd · Hospital de Niños Ricardo Gutierrez

  • Silvana Figar, MD MG · Hospital Italiano de Buenos Aires

  • Andrea Gamarnick, Phd · National Council of Scientific and Technical Research, Argentina

  • Ana Maria Gomez Saldaño, MD MG · Salud Comunitaria Ministerio de Salud del Gobierno de la Ciudad de Buenos Aires

  • Lorena Luna · Salud Comunitaria Ministerio de Salud del Gobierno de la Ciudad de Buenos Aires

  • Julieta Salto · Salud Comunitaria Ministerio de Salud del Gobierno de la Ciudad de Buenos Aires

  • Magdalena Wagner Manslau · Salud Comunitaria Ministerio de Salud del Gobierno de la Ciudad de Buenos Aires

  • Fernan Quiroz, MD MG · Ministerio de Salud del Gobierno de la Ciudad de Buenos Aires

Eligibility

Min Age
14 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-12-02
Primary Completion
2021-08-20
Completion
2021-08-20

Countries

  • Argentina

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04673279 on ClinicalTrials.gov