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Frailty, Immunonutrition, Surgery Type, and Biologic Recovery in Elderly Gastric Cancer

NCT07803159 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 328

Last updated 2026-09-03

No results posted yet for this study

Summary

This prospective observational cohort study will evaluate the effects of multidimensional frailty phenotypes, immunonutritional status, and surgical approach on biological recovery in patients aged 60 years and older undergoing surgery for gastric cancer. Preoperative assessment will include physical and cognitive frailty, nutritional status, handgrip strength, and skeletal muscle characteristics on computed tomography. Patients will be followed prospectively during the perioperative period, including assessment of inflammatory markers, postoperative complications, delirium, hospital length of stay, and functional recovery. The study aims to determine whether multidimensional frailty and immunonutritional factors are associated with postoperative outcomes and whether surgical approach influences biological recovery in older patients with gastric cancer. A total of 328 patients are planned to be included at Kocaeli City Hospital.

Conditions

Interventions

PROCEDURE

Laparoscopic Gastrectomy

Elective radical gastrectomy performed using a laparoscopic approach as part of routine clinical care. The surgical approach is not assigned by the study

PROCEDURE

Open Gastrectomy

Elective radical gastrectomy performed using an open approach as part of routine clinical care. The surgical approach is not assigned by the study

Sponsors & Collaborators

  • Kocaeli City Hospital

    lead OTHER_GOV

Principal Investigators

  • Adem Yuksel, Assoc.Prof. · Kocaeli City Hospital

Eligibility

Min Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-09-30
Primary Completion
2028-08-31
Completion
2028-08-31

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07803159 on ClinicalTrials.gov