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Biofluid Research on Age-Related or Inherited Neurodegeneration

NCT07798700 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000

Last updated 2026-09-01

No results posted yet for this study

Summary

The aim of this study is to contribute to and continue to sustain a repository of blood samples, nucleic acid (DNA and/or RNA) samples, family history information, and other demographic information from individuals with age-related neurodegenerative conditions, or their family members who may or may not be at risk for similar conditions. This study will continue to further expand research into the molecular and genetic basis of these diseases and their risk factors.

Conditions

  • Frontotemporal Degeneration (FTD)
  • ALS (Amyotrophic Lateral Sclerosis)
  • Primary Progressive Aphasia (PPA)
  • Familial Frontotemporal Lobar Degeneration (fFTLD)
  • Fronto-temporal Lobar Dementia
  • Dementia With Lewy Bodies (DLB)
  • Cortical Basal Syndrome (CBS)
  • Alzheimer's Disease (AD)
  • Progressive Supranuclear Palsy(PSP)
  • Parkinson's Disease (PD)
  • Parkinson's Disease Dementia (PDD)
  • Limbic-predominant Age-related TDP-43 Encephalopathy (LATE)
  • Posterior Cortical Atrophy (PCA)
  • Primary Lateral Sclerosis (PLS)
  • Primary Muscular Atrophy (PMA)

Sponsors & Collaborators

  • University of Pennsylvania Institute on Aging

    collaborator OTHER

  • National Institute on Aging (NIA)

    collaborator NIH

  • National Institute of Neurological Disorders and Stroke (NINDS)

    collaborator NIH

  • University of Pennsylvania

    lead OTHER

Principal Investigators

  • Corey McMillan, PhD · University of Pennsylvania

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-12-12
Primary Completion
2070-01-01
Completion
2070-01-01

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07798700 on ClinicalTrials.gov