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Biomarker Profiling in Individuals at Risk for Prion Disease

NCT05124392 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2026-04-22

No results posted yet for this study

Summary

We are doing this research to identify biomarkers in individuals who are at-risk for familial prion disease. We hope to use these biomarkers to predict timing of disease onset in pre-symptomatic individuals and to guide the direction of future clinical trials.

Conditions

  • FFI
  • CJD (Creutzfeldt Jakob Disease)
  • Prion Diseases
  • GSS
  • Familial Fatal Insomnia

Sponsors & Collaborators

Principal Investigators

  • Steven E Arnold, MD · MGH

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-12-01
Primary Completion
2027-06-01
Completion
2027-06-01

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05124392 on ClinicalTrials.gov