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FIB-4 Index, Sleep Apnea Severity, and Nocturnal Hypoxemia

NCT07798518 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 373

Last updated 2026-09-01

No results posted yet for this study

Summary

This retrospective study evaluates whether the Fibrosis-4 (FIB-4) index is associated with the severity of obstructive sleep apnea (OSA) and nighttime oxygen desaturation. Adults who underwent full-night polysomnography were grouped according to apnea-hypopnea index (AHI) as no OSA, mild OSA, moderate OSA, or severe OSA. Routine clinical, laboratory, and sleep-study data were reviewed.

The main aim is to compare FIB-4 values across OSA severity groups and to examine whether FIB-4 is related to AHI, oxygen desaturation index (ODI), and minimum oxygen saturation during sleep. The study also evaluates the proportion of patients with FIB-4 values at or above 1.30, a commonly used threshold for identifying individuals who may need further liver fibrosis assessment.

FIB-4 is used in this study as a noninvasive liver fibrosis risk marker and not as a diagnosis of liver fibrosis.

Conditions

Sponsors & Collaborators

  • Hisar Intercontinental Hospital

    lead OTHER

Principal Investigators

  • Bekir Sami Uyanık, MD, · Hisar Hospital Intercontinental

  • Orhan Dalkılıç, MD · Hisar Hospital Intercontinental

  • Süleyman Hilmi İpekçi, MD · Hisar Hospital Intercontinental

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-01-01
Primary Completion
2026-07-31
Completion
2026-07-31

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07798518 on ClinicalTrials.gov