Prevalence of Non-alcoholic Fatty Liver Disease Among Non-obese Obstructive Sleep Apnea by Using Transient Elastography
NCT05351515 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 1000
Last updated 2023-08-30
Summary
Obstructive sleep apnea (OSA) and non-alcoholic fatty liver disease (NAFLD) are both common diseases related to metabolic diseases with potential cardiovascular consequences and liver complications respectively. Though studies show OSA may take part in the progression of hepatic steatosis, the independent contribution of OSA on liver fat accumulation is unknown. It is hypothesized that nocturnal intermittent hypoxia from OSA is the main driver of NAFLD in non-obese OSA patients. This study is to assess the effect of OSA on NAFLD in non-obese patients.
Conditions
- Sleep Apnea, Obstructive
- Fatty Liver
Sponsors & Collaborators
-
Chinese University of Hong Kong
lead OTHER
Principal Investigators
-
David Hui · Chinese University of Hong Kong
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-04-30
- Primary Completion
- 2025-01-31
- Completion
- 2025-01-31
Countries
- Hong Kong
Study Locations
More Related Trials
-
Prevalence of Obstructive Sleep Apnea (OSA) and the Association With Cognitive Impairment
NCT04658290 ·Status: RECRUITING
-
Fat Metabolism in OSA and COPD
NCT02157844 ·Status: COMPLETED
-
Fatty Liver and Obstructive Sleep Apnea
NCT00730873 ·Status: COMPLETED ·Phase: NA
-
A Brief Lifestyle Modification Programme in Overweight Subjects With Obstructive Sleep Apnoea - Needs Assessment
NCT04262986 ·Status: UNKNOWN
-
A Cross-sectional Study of the Occurrence and Effect of Obstructive Sleep Apnea in Subjects With Resistant Hypertension
NCT00843583 ·Status: COMPLETED
-
Prevalence of Sleep Apnoea in Adolescents
NCT03895775 ·Status: RECRUITING
-
Relationship Between Normal-weight Central Obesity and Obstructive Sleep Apnea
NCT04061226 ·Status: COMPLETED
-
Effects of CPAP on Visceral Fat Thickness
NCT01828281 ·Status: COMPLETED ·Phase: NA
-
Sleep Apnea, Neurocognitive Decline and Brain Imaging in Patients With Subjective or Mild Cognitive Impairment
NCT06150352 ·Status: RECRUITING
-
Dynamic Alterations of Tongue in Sleep Apnoea Hypopnea Syndrome During Sleep
NCT01687855 ·Status: COMPLETED
-
The Interplay Between Obstructive Sleep Apnea Cognitive Dysfunction in Pediatric Patients
NCT05421403 ·Status: COMPLETED ·Phase: NA
-
Prevalence of OSA in Patients of ILD
NCT06058052 ·Status: UNKNOWN
-
Prevalence of OSAS in Chinese Elderly and Its CPAP Compliance
NCT02085720 ·Status: COMPLETED ·Phase: NA
-
An 18-year Follow-up Study on OSA in a Population-based Cohort
NCT05077748 ·Status: COMPLETED
-
Predictors of OSA in Patients With COPD
NCT05605431 ·Status: COMPLETED
-
Prevalence, Phenotypes, Predictors and Prognostic Implication of Obstructive Sleep Apnea in Pulmonary Hypertension
NCT05595200 ·Status: RECRUITING
-
Sleep Apnea in a Non-Clinical Population
NCT00005551 ·Status: COMPLETED
-
Pathophysiological Study of CSA in Adults With pLVEF
NCT03919344 ·Status: TERMINATED ·Phase: NA
-
The Epidemiology of Sleep Disordered Breathing in Patients With Congestive Heart Failure
NCT05332223 ·Status: COMPLETED
-
The Impact of Sleep Apnea Treatment on Physiology Traits in Chinese Patients With Obstructive Sleep Apnea
NCT02696629 ·Status: UNKNOWN
-
Physical Status of OSA Patients
NCT05051514 ·Status: COMPLETED
-
The Prevalence of Sleep Disordered Breathing in Hospitalized Patients With Acutely Decompensated Heart Failure Syndrome
NCT00701519 ·Status: COMPLETED
-
Sleep Apnea in Acromegaly After Surgery
NCT03526016 ·Status: UNKNOWN
-
Effect of Weight Loss and CPAP on OSA and Metabolic Profile Stratified by Craniofacial Phenotype
NCT03287973 ·Status: COMPLETED ·Phase: NA
-
Digital-supported Orofacial Myofunctional Therapy in OSA
NCT07292922 ·Status: RECRUITING ·Phase: NA