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Evaluation Of Patients With Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) Based on Nonlinear Analysis Of Respiratory Signals

NCT01161381 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2010-07-13

No results posted yet for this study

Summary

Objective: Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) is a common sleep disorder requiring the time and money consuming full polysomnography to be diagnosed. Alternative methods for initial evaluation are sought. The investigators aim was the prediction of Apnea-Hypopnea Index (AHI) in patients suspected to suffer from OSAHS using two models based on nonlinear analysis of three biosignals during sleep.

Methods: One hundred patients referred to a Sleep Unit underwent full polysomnography. Three nonlinear indices (Largest Lyapunov Exponent, Detrended Fluctuation Analysis and Approximate Entropy) were extracted from three biosignals (airflow from a nasal cannula, thoracic movement and Oxygen saturation) providing input to a data mining application for the creation of predictive models for AHI.

Conditions

  • Obstructive Sleep Apnea Syndrome (OSAS)

Interventions

DEVICE

Estimation of nonlinear indices from Polysomnography

All subjects underwent full night polysomnography. Three nonlinear indices (Largest Lyapunov Exponent, Detrended Fluctuation Analysis and Approximate Entropy) were extracted from three biosignals (airflow from a nasal cannula, thoracic movement and Oxygen saturation) providing input to a data mining application for the creation of predictive models for AHI.

Sponsors & Collaborators

  • Greek State Scholarship Foundation

    collaborator UNKNOWN

  • Aristotle University Of Thessaloniki

    lead OTHER

Principal Investigators

  • Evangelos K Kaimakamis, MD, MSc · Aristotle University Of Thessaloniki

  • Nikolaos Maglaveras, PhD · Aristotle University Of Thessaloniki

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2005-11-30
Primary Completion
2009-12-31
Completion
2009-12-31

Countries

  • Greece

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01161381 on ClinicalTrials.gov