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Postoperative Care After Tonsillectomy

NCT07792057 · Status: NOT_YET_RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 300

Last updated 2026-08-28

No results posted yet for this study

Summary

Tonsillectomy is one of the most common surgical procedures performed on both pediatric and adult patients; it is frequently associated with significant postoperative pain, difficulty swallowing, and the risk of complications such as bleeding and infection. The recovery period requires care aimed at minimizing discomfort, promoting healing, and preventing adverse events. Metabolic demands increase postoperatively due to surgical stress and the tissue repair process. Adequate nutrition, with a focus on protein intake, is fundamental for the synthesis of new proteins, the repair of injured tissues, and the maintenance of immune function-all essential for rapid, effective recovery and the prevention of complications. Insufficient protein intake can compromise surgical wound healing and the immune response.

Additionally, the integrity and hydration of the oropharyngeal mucosa are crucial following a tonsillectomy. Surgical trauma and exposure to ambient air (especially after anesthesia and intubation) can lead to mucosal dryness, pain, discomfort, and scab formation, potentially hindering healing and increasing the risk of secondary infections. Micronebulization with saline solutions emerges as a potential intervention to hydrate the mucosa, alleviate discomfort, and promote the healing process. Despite the recognized importance of nutrition and local humidification, evidence regarding the combined impact of protein supplementation strategies and the use of micronebulizers on the recovery of patients undergoing tonsillectomy-specifically within a randomized clinical trial-requires further investigation. This study aims to contribute to the evidence base by evaluating the efficacy of these combined interventions on relevant clinical outcomes.

Conditions

  • Tonsillectomy
  • Bleeding
  • Nutrition
  • Healing

Interventions

DIETARY_SUPPLEMENT

Nutrition and Hydration

* Optimized Protein Nutrition: Following the fasting period and as tolerated, patients will receive a diet with individualized protein supplementation, aiming to achieve a protein intake of \[1.3 g/kg/day for children and 2 g/kg/day for adults\]. Supplementation may be administered orally (liquid or powdered nutritional supplements, fortified foods) or, if necessary, via enteral tube. Protein intake will be monitored daily by the nutrition team. * Mucosal Humidification: Micro-nebulization sessions using 10 mL of 0.9% normal saline will be performed every 8 hours with a standard micro-nebulizer for a period of 20 days. Patients or their caregivers will be instructed on the correct technique.

Sponsors & Collaborators

  • Hospital Felicio Rocho

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
2 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-09-01
Primary Completion
2027-09-01
Completion
2028-01-01

Countries

  • Brazil

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07792057 on ClinicalTrials.gov