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Hemodynamic Responses to Laryngoscopy and Tracheal Intubation

NCT07783256 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 70

Last updated 2026-08-24

No results posted yet for this study

Summary

Laryngoscopy and tracheal intubation lead to tachycardia and hypertension due to increase in the plasma catecholamines subsequent to sympathetic stimulation.

Conditions

  • Hemodynamic Response to Laryngoscopy and Tracheal Intubation

Interventions

DRUG

ketodex

Patients will receive a single IV bolus dose of both ketamine and dexmedetomidine

DRUG

ketofol

Patients will receive a single IV bolus dose of both ketamine and propofol

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Seham M Moeen, M.D. · Assiut University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-12-20
Primary Completion
2028-12-20
Completion
2028-12-20

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07783256 on ClinicalTrials.gov