The FLARE (Flurpiridaz vs. Rubidium Evaluation) Trial
NCT07761728 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 60
Last updated 2026-08-12
Summary
This study seeks to evaluate if the diagnostic performance of 18F-flurpiridaz positron emission tomography (PET) myocardial perfusion imaging (MPI), given the radiotracer's properties, is non-inferior to the currently most widely utilized PET MPI radiopharmaceutical, 82Rb-chloride.
Conditions
- Coronary Artery Disease
- Coronary Microvascular Disease
Sponsors & Collaborators
-
VA Greater Los Angeles Healthcare System
collaborator FED -
University of California, Los Angeles
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-08-13
- Primary Completion
- 2026-12-31
- Completion
- 2027-01-31
Countries
- United States
Study Locations
More Related Trials
-
Plaque Burden and Ischemia in MINOCA
NCT05681858 ·Status: RECRUITING
-
Florbetaben for Imaging of Vascular Amyloid
NCT06091319 ·Status: RECRUITING
-
An International Study to Evaluate Diagnostic Efficacy of Flurpiridaz (18F) Injection PET MPI in the Detection of Coronary Artery Disease (CAD)
NCT03354273 ·Status: COMPLETED ·Phase: PHASE3
-
Vascular Inflammation ReDuction and Perivascular Fat Imaging by Computed Tomography
NCT06083337 ·Status: RECRUITING ·Phase: NA
-
PET MYOCARDIAL Blood Flow Comparison to Coronary CTA and CT-FFR
NCT05349084 ·Status: COMPLETED ·Phase: NA
-
Study to Determine the Clinical Significance of Intravascular OCT-NIRAF
NCT06374498 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
MR INFORM - MR Perfusion Imaging to Guide Management of Patients With Stable Coronary Artery Disease
NCT01236807 ·Status: COMPLETED ·Phase: NA
-
In-vivo Thrombus Imaging With 18F-GP1, a Novel Platelet PET Radiotracer
NCT03943966 ·Status: COMPLETED ·Phase: NA
-
BFPET for Regional Myocardial Perfusion Imaging
NCT02252783 ·Status: UNKNOWN ·Phase: PHASE2
-
Concurrent OCT and FFR-guided PCI in CAD
NCT06182683 ·Status: RECRUITING ·Phase: NA
-
FFRangio Accuracy vs. Standard FFR
NCT03226262 ·Status: COMPLETED
-
18F-PBR06/Total Body PET Imaging in Patients With STEMI
NCT05269446 ·Status: COMPLETED
-
Angiogram Based Fractional Flow Reserve FFRangio - A Validation Study
NCT03005028 ·Status: COMPLETED
-
CardioPET as PET Imaging Agent to Assess Myocardial Perfusion and Fatty Acid Uptake in Known or Suspected CAD Subjects
NCT01826773 ·Status: COMPLETED ·Phase: PHASE2
-
Positron Emission Tomography (PET) Imaging of Thrombosis
NCT03830320 ·Status: RECRUITING ·Phase: PHASE1
-
A Phase I Study to Evaluate BFPET as a Potential Myocardial Perfusion Imaging(MPI) Agent for PET
NCT00733460 ·Status: COMPLETED ·Phase: PHASE1
-
Assessment of Renal Microcirculation With Rubidium Positron Emission Tomography
NCT06332456 ·Status: COMPLETED
-
Prediction of Recurrent Events With 18F-Fluoride
NCT02278211 ·Status: COMPLETED
-
Rubidium-82 PET and Tc-99m-MIBI SPET: A Head to Head Comparison
NCT01379677 ·Status: COMPLETED ·Phase: PHASE3
-
The Value of CT-FFR Compared to CCTA or CCTA and Stress MPI in Low to Intermediate Risk ED Patients With Toshiba CT-FFR
NCT03329469 ·Status: UNKNOWN
-
Angiogram Based Fractional Flow Reserve in Patients With Multi-Vessel Disease
NCT03455244 ·Status: COMPLETED
-
Clinical Impact of Cardiac Photon-Counting Detector CT
NCT05240807 ·Status: COMPLETED ·Phase: NA
-
Evaluation of Exposure Reduction Using Region-of-Interest Fluoroscopy (X-ray Fovea Imaging) in Cardiac Interventions
NCT00817115 ·Status: UNKNOWN ·Phase: PHASE1
-
Residual Inflammation and Plaque Progression Long-term Evaluation
NCT04073810 ·Status: ACTIVE_NOT_RECRUITING
-
Diagnostic Accuracy to Detect Hemodynamically Significant Stenosis by Non-invasive SURECardio CT-FFR
NCT03055780 ·Status: COMPLETED