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18F-PBR06/Total Body PET Imaging in Patients With STEMI

NCT05269446 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 26

Last updated 2024-11-12

No results posted yet for this study

Summary

The study will use 18F-PBR06/uExplorer to study the activation of macrophages and systemic perfusion in patients with ST-segment elevation myocardial infarction (STEMI) or stable angina (SA). Participants will receive the total-body PET/CT scan on the seventh day (Day 7, D7) and D180 of enrolment.

Conditions

Interventions

PROCEDURE

percutaneous coronary intervention (PCI)

A family of minimally invasive procedures used to open clogged coronary arteries and restore blood flow. This is also a standard treatment for patients diagnosed with STEMI or SA

DEVICE

total body PET/CT scan

all participants will receive a total-body PET/CT scan (uExplorer) after enrolment

PROCEDURE

Coronary Angiography (CAG)

A procedure that uses X-ray imaging to visualize coronary arteries.

DRUG

TSPO injection

Participants will receive one dose of the non-therapeutic administration of the radioactive TSPO tracer 18F-PBR06 before a whole-body scan by uExplorer

Sponsors & Collaborators

  • RenJi Hospital

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-07-08
Primary Completion
2024-05-31
Completion
2024-11-10

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05269446 on ClinicalTrials.gov