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Effect of Sage Extract Supplementation on Cognitive Function in Middle-Aged Men and Women

NCT07757529 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 64

Last updated 2026-08-11

No results posted yet for this study

Summary

Sage (Salvia officinalis) has been reported to have antioxidant, anti-inflammatory, and neuroprotective properties. Several studies indicate that sage supplementation can improve cognitive function. However, more research is needed. The purpose of this study is to examine how sage supplementation affects cognitive function and reaction times in middle-aged men and women.

Conditions

  • Cognitive Ability, General

Interventions

DIETARY_SUPPLEMENT

SageXtra

333 mg/day of SageXtra sage extract powder in two #0 capsules (167 mg/capsule).

DIETARY_SUPPLEMENT

Placebo

333 mg/day of methylcellulose powder in two #0 capsules.

Sponsors & Collaborators

  • Exercise & Sport Nutrition Lab, Texas A&M University

    collaborator UNKNOWN

  • ESM Technologies, LLC

    lead INDUSTRY

Principal Investigators

  • Kevin J. Ruff, Ph.D. · ESM Technologies, LLC

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-02-15
Primary Completion
2026-10-31
Completion
2026-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07757529 on ClinicalTrials.gov