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Swap Anesthetic Versus Continuous Desflurane in Adults Undergoing Bariatric Surgery

NCT07748247 · Status: NOT_YET_RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 82

Last updated 2026-08-05

No results posted yet for this study

Summary

This randomized, parallel-group, non-inferiority clinical trial aims to evaluate whether an anesthetic swap strategy consisting of sevoflurane followed by desflurane 30 minutes before the end of surgery is non-inferior to continuous desflurane anesthesia with respect to extubation time in adults undergoing elective laparoscopic bariatric surgery. Secondary outcomes include time to achieve a Patient State Index (PSi) greater than 80, time to achieve an Aldrete score of at least 8, incidence of postoperative nausea and vomiting, post-anesthesia care unit length of stay, and desflurane-related costs.

Conditions

Interventions

DRUG

Desflurane

Desflurane administered as the inhalational anesthetic throughout the surgical procedure.

DRUG

Sevoflurane-Desflurane

Sevoflurane administered during the initial phase of surgery followed by desflurane beginning 30 minutes before surgical closure.

Sponsors & Collaborators

  • Clínica Dávila

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-08-03
Primary Completion
2027-04-30
Completion
2027-04-30

Countries

  • Chile

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07748247 on ClinicalTrials.gov