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Research Title: Long Term Functional Outcome of a Single Hyaluronic Acid Injection in Improving Symptoms and Function in Patients With Knee Osteoarthritis - A Single-Arm Open-Label Study (DIART ONE).

NCT07736781 · Status: NOT_YET_RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 62

Last updated 2026-07-30

No results posted yet for this study

Summary

This study aims to evaluate the effectiveness of a single HA injection in improving pain, function, and quality of life in patients with knee OA over a 12-month period. By focusing on a single-arm open-label design, this study will provide practical insights into the real-world application of this treatment approach.

Conditions

  • Osteo Arthritis of the Knee

Interventions

DRUG

Hyaluronic Acid (HA)

single injection of hyaluronic acid ( Diart) into the affected knee

Sponsors & Collaborators

  • Hospital Universiti Sains Malaysia

    collaborator OTHER

  • Universiti Sains Malaysia

    lead OTHER

Principal Investigators

  • AMRAN AHMED SHOKRI, MASTER IN ORTHOPEDIC · Universiti Sains Malaysia

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
40 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-08-30
Primary Completion
2028-08-30
Completion
2029-08-30

Countries

  • Malaysia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07736781 on ClinicalTrials.gov