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Evaluation of the Effect of a Seaweed Flour- and Leucine-Enriched Food on Metabolic and Inflammatory Status in Older Adults With Probable Sarcopenia or Sarcopenia

NCT07689994 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 102

Last updated 2026-07-08

No results posted yet for this study

Summary

Sarcopenia and probable sarcopenia are associated with loss of muscle strength, functional impairment, frailty, and an increased risk of adverse outcomes in older adults. In short-term interventions, structural or functional changes may be modest, whereas certain serum biomarkers of metabolic-nutritional response may be more sensitive. In this protocol version, serum transthyretin (TTR) has been selected as the primary outcome, without assuming that it represents, by itself, a direct measure of muscle mass or overall clinical efficacy.

Conditions

  • Sarcopenia in Elderly

Interventions

DIETARY_SUPPLEMENT

Standard chocolate-flavored cake

Participants will consume one standard chocolate-flavored cake serving daily for 28 days, without added leucine or seaweed flour.

DIETARY_SUPPLEMENT

Leucine-Enriched Chocolate Cake

Participants will consume one chocolate-flavored cake serving supplemented with 3 g of leucine daily for 28 days.

DIETARY_SUPPLEMENT

Leucine Plus Seaweed Flour-Enriched Chocolate Cake

Participants will consume one chocolate-flavored cake serving supplemented with 3 g of leucine and 3 g of Durvillaea incurvata flour daily for 28 days.

Sponsors & Collaborators

  • Finis Terrae University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-08-01
Primary Completion
2026-10-01
Completion
2027-03-01

Countries

  • Chile

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07689994 on ClinicalTrials.gov