MedTrace Logo

Effects of Using Miswak in Addition to Oral Hygiene Products in Patients With Gingivitis

NCT07689786 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 36

Last updated 2026-07-08

No results posted yet for this study

Summary

This pilot study aims to evaluate the effects of miswak use on the oral biological environment by comparing biochemical parameters obtained from saliva and dental plaque samples collected from individuals who use miswak and controls. A total of 36 healthy volunteers will be enrolled in the study, including 18 miswak+rutine oral hygiene products users and 18 rutine oral hygiene products.

Periodontal clinical parameters will be recorded, and saliva and supragingival dental plaque samples will be collected from all participants. The collected samples will be analysed for biomarkers associated with periodontal inflammation and oxidative stress. Interleukin-1 beta (IL-1β), C-reactive protein (CRP), and oxidative stress levels will be measured using biochemical analysis.

The findings of this study are expected to provide preliminary evidence regarding the biological effects of miswak on oral health and contribute to the current understanding of its potential role as an adjunctive oral hygiene tool.

Conditions

  • Gingivitis; Chronic

Interventions

COMBINATION_PRODUCT

Miswak

Participants used miswak (Salvadora persica L.) as an adjunct to toothbrushing, five times per day, for one month before periodontal treatment.

OTHER

Toothpaste

Participants used a manual toothbrush twice daily for one month before periodontal treatment.

Sponsors & Collaborators

  • Mustafa Kemal University

    lead OTHER

Principal Investigators

  • Hasan Burak Sen, DDs · Hatay Mustafa Kemal Üniversitesi

  • Ayşegül Sari, PhD · Hatay Mustafa Kemal Üniversitesi

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-07-04
Primary Completion
2027-07-04
Completion
2027-07-04

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07689786 on ClinicalTrials.gov