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Effect of Ozone Therapy on Marginal Bone Levels Around Dental Implants

NCT07687641 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2026-09-04

No results posted yet for this study

Summary

This prospective split-mouth randomized clinical trial was conducted to evaluate the effect of ozone treatment applied to fresh implant sockets on marginal bone levels and bone microarchitecture following immediate implant placement. Each participant received ozone treatment at one implant site and conventional treatment at the contralateral site according to a randomized allocation. Marginal bone levels and bone microarchitecture were evaluated using cone-beam computed tomography (CBCT) and fractal analysis over a 6-month follow-up period.

Conditions

  • Immediate Dental Implant Placement
  • Effects of Gaseous Ozone on Marginal Bone Levels

Interventions

PROCEDURE

Gaseous Ozone Application

Gaseous ozone was applied to the fresh implant socket immediately before immediate implant placement.

PROCEDURE

Conventional Implant Placement

Implant placement was performed without gaseous ozone application.

Sponsors & Collaborators

  • Adiyaman University

    lead OTHER

Principal Investigators

  • METİN ÇALIŞIR, PhD · Department of Periodontology, Faculty of Dentistry, Adıyaman University, Adıyaman, Turkey

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-09-03
Primary Completion
2026-03-27
Completion
2026-05-18

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07687641 on ClinicalTrials.gov